| Full name: glycine receptor beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q32.1 | ||
| Entrez ID: 2743 | HGNC ID: HGNC:4329 | Ensembl Gene: ENSG00000109738 | OMIM ID: 138492 |
| Drug and gene relationship at DGIdb | |||
Expression of GLRB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLRB | 2743 | 205279_s_at | 0.1893 | 0.8282 | |
| GSE20347 | GLRB | 2743 | 205279_s_at | 0.1220 | 0.0239 | |
| GSE23400 | GLRB | 2743 | 205279_s_at | 0.0187 | 0.4862 | |
| GSE26886 | GLRB | 2743 | 205279_s_at | 0.1804 | 0.1301 | |
| GSE29001 | GLRB | 2743 | 205279_s_at | 0.0863 | 0.5876 | |
| GSE38129 | GLRB | 2743 | 205279_s_at | 0.0104 | 0.9296 | |
| GSE45670 | GLRB | 2743 | 205279_s_at | 0.0062 | 0.9728 | |
| GSE53622 | GLRB | 2743 | 24571 | -0.2417 | 0.0223 | |
| GSE53624 | GLRB | 2743 | 24571 | -0.0419 | 0.4909 | |
| GSE63941 | GLRB | 2743 | 205279_s_at | -1.3339 | 0.2677 | |
| GSE77861 | GLRB | 2743 | 205279_s_at | -0.0710 | 0.5900 | |
| SRP064894 | GLRB | 2743 | RNAseq | -0.1793 | 0.6234 | |
| SRP133303 | GLRB | 2743 | RNAseq | 0.2087 | 0.6216 | |
| SRP159526 | GLRB | 2743 | RNAseq | 1.2487 | 0.0125 | |
| TCGA | GLRB | 2743 | RNAseq | -0.8183 | 0.0147 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GLRB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLRB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLRB | 2743 | 0 | 16 | 14 | |
| GSE20123 | GLRB | 2743 | 0 | 15 | 15 | |
| GSE43470 | GLRB | 2743 | 0 | 14 | 29 | |
| GSE46452 | GLRB | 2743 | 1 | 36 | 22 | |
| GSE47630 | GLRB | 2743 | 0 | 23 | 17 | |
| GSE54993 | GLRB | 2743 | 10 | 0 | 60 | |
| GSE54994 | GLRB | 2743 | 1 | 12 | 40 | |
| GSE60625 | GLRB | 2743 | 0 | 1 | 10 | |
| GSE74703 | GLRB | 2743 | 0 | 12 | 24 | |
| GSE74704 | GLRB | 2743 | 0 | 8 | 12 | |
| TCGA | GLRB | 2743 | 11 | 35 | 50 |
Total number of gains: 23; Total number of losses: 172; Total Number of normals: 293.
Somatic mutations of GLRB:
Generating mutation plots.
Highly correlated genes for GLRB:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLRB | CEP112 | 0.638947 | 3 | 0 | 3 |
| GLRB | ST18 | 0.632818 | 3 | 0 | 3 |
| GLRB | LIFR | 0.630863 | 3 | 0 | 3 |
| GLRB | NLGN4Y | 0.624105 | 3 | 0 | 3 |
| GLRB | DENND5B | 0.616362 | 4 | 0 | 3 |
| GLRB | PNMA2 | 0.592603 | 4 | 0 | 3 |
| GLRB | LRRTM4 | 0.590433 | 4 | 0 | 3 |
| GLRB | KCNA3 | 0.559593 | 4 | 0 | 3 |
| GLRB | ZNF510 | 0.550494 | 5 | 0 | 3 |
| GLRB | MLPH | 0.540224 | 4 | 0 | 3 |
| GLRB | MMP27 | 0.523492 | 4 | 0 | 3 |
| GLRB | NELL1 | 0.507805 | 4 | 0 | 3 |
| GLRB | GNAZ | 0.506658 | 4 | 0 | 3 |
| GLRB | PIP5K1B | 0.505602 | 5 | 0 | 4 |
| GLRB | TEX14 | 0.505049 | 6 | 0 | 3 |
| GLRB | ACKR4 | 0.502022 | 4 | 0 | 3 |
For details and further investigation, click here
