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File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
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Multi-Omics Database of ESCC

 

PNMA2

 

Full name: PNMA family member 2 Alias Symbol: MA2|RGAG2
Type: protein-coding gene Cytoband: 8p21.2
Entrez ID: 10687 HGNC ID: HGNC:9159 Ensembl Gene: ENSG00000240694 OMIM ID: 603970
Drug and gene relationship at DGIdb

 

Expression of PNMA2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PNMA2 10687 209598_at -0.7310 0.3586
GSE20347 PNMA2 10687 209597_s_at -0.0121 0.8675
GSE23400 PNMA2 10687 209598_at 0.0659 0.4331
GSE26886 PNMA2 10687 209597_s_at 0.2415 0.0533
GSE29001 PNMA2 10687 209598_at 0.2986 0.3168
GSE38129 PNMA2 10687 209598_at -0.2835 0.4991
GSE45670 PNMA2 10687 209597_s_at 0.0272 0.8343
GSE63941 PNMA2 10687 209598_at -6.1162 0.0000
GSE77861 PNMA2 10687 209597_s_at 0.0978 0.5245
SRP007169 PNMA2 10687 RNAseq 2.4476 0.0204
SRP064894 PNMA2 10687 RNAseq 1.1987 0.0029
SRP133303 PNMA2 10687 RNAseq 0.5092 0.1189
SRP159526 PNMA2 10687 RNAseq 0.6871 0.3785
SRP193095 PNMA2 10687 RNAseq 0.3852 0.1502
SRP219564 PNMA2 10687 RNAseq 1.3261 0.1434
TCGA PNMA2 10687 RNAseq -0.9834 0.0024

Upregulated datasets: 2; Downregulated datasets: 1.  

 

Survival by PNMA2 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of PNMA2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PNMA2 10687 4 12 14
GSE20123 PNMA2 10687 4 12 14
GSE43470 PNMA2 10687 4 7 32
GSE46452 PNMA2 10687 13 13 33
GSE47630 PNMA2 10687 10 8 22
GSE54993 PNMA2 10687 2 15 53
GSE54994 PNMA2 10687 9 16 28
GSE60625 PNMA2 10687 3 0 8
GSE74703 PNMA2 10687 4 6 26
GSE74704 PNMA2 10687 3 8 9
TCGA PNMA2 10687 14 44 38

Total number of gains: 70; Total number of losses: 141; Total Number of normals: 277.  

 

Somatic mutations of PNMA2:

 

Generating mutation plots.

 

Highly correlated genes for PNMA2:

 

Showing top 20/384 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PNMA2NME50.887419303
PNMA2HSPB20.790741303
PNMA2ASPA0.789287303
PNMA2GYPC0.785036303
PNMA2CCDC690.784651303
PNMA2LMOD10.781111303
PNMA2ACTG20.748046303
PNMA2INMT0.744748303
PNMA2ANXA60.741503404
PNMA2BMP40.737492303
PNMA2LINC011400.732711303
PNMA2FAT40.726883403
PNMA2LAMA20.718588403
PNMA2ADAMTS50.71399403
PNMA2SCN3A0.712606403
PNMA2FBXL70.710918403
PNMA2CNN10.708582303
PNMA2DPT0.70712404
PNMA2TCEAL70.706523303
PNMA2NPBWR10.705261303

For details and further investigation, click here