| Full name: neural EGFL like 1 | Alias Symbol: IDH3GL|FLJ45906 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 4745 | HGNC ID: HGNC:7750 | Ensembl Gene: ENSG00000165973 | OMIM ID: 602319 |
| Drug and gene relationship at DGIdb | |||
Expression of NELL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NELL1 | 4745 | 206089_at | -0.0626 | 0.9231 | |
| GSE20347 | NELL1 | 4745 | 206089_at | -0.0251 | 0.8675 | |
| GSE23400 | NELL1 | 4745 | 206089_at | -0.1329 | 0.0708 | |
| GSE26886 | NELL1 | 4745 | 206089_at | -0.0526 | 0.8113 | |
| GSE29001 | NELL1 | 4745 | 206089_at | -0.0377 | 0.8922 | |
| GSE38129 | NELL1 | 4745 | 206089_at | -0.0358 | 0.9091 | |
| GSE45670 | NELL1 | 4745 | 206089_at | -0.0946 | 0.6770 | |
| GSE53622 | NELL1 | 4745 | 31928 | -0.5676 | 0.0172 | |
| GSE53624 | NELL1 | 4745 | 31928 | -0.4189 | 0.0514 | |
| GSE63941 | NELL1 | 4745 | 206089_at | 0.1512 | 0.2476 | |
| GSE77861 | NELL1 | 4745 | 206089_at | 0.0372 | 0.8583 | |
| GSE97050 | NELL1 | 4745 | A_33_P3354203 | -0.0760 | 0.7519 | |
| TCGA | NELL1 | 4745 | RNAseq | -0.8855 | 0.3253 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NELL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NELL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NELL1 | 4745 | 0 | 11 | 19 | |
| GSE20123 | NELL1 | 4745 | 0 | 11 | 19 | |
| GSE43470 | NELL1 | 4745 | 1 | 6 | 36 | |
| GSE46452 | NELL1 | 4745 | 7 | 5 | 47 | |
| GSE47630 | NELL1 | 4745 | 3 | 10 | 27 | |
| GSE54993 | NELL1 | 4745 | 3 | 0 | 67 | |
| GSE54994 | NELL1 | 4745 | 4 | 11 | 38 | |
| GSE60625 | NELL1 | 4745 | 0 | 0 | 11 | |
| GSE74703 | NELL1 | 4745 | 1 | 4 | 31 | |
| GSE74704 | NELL1 | 4745 | 0 | 9 | 11 | |
| TCGA | NELL1 | 4745 | 13 | 26 | 57 |
Total number of gains: 32; Total number of losses: 93; Total Number of normals: 363.
Somatic mutations of NELL1:
Generating mutation plots.
Highly correlated genes for NELL1:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NELL1 | SAG | 0.759618 | 3 | 0 | 3 |
| NELL1 | LIPF | 0.755921 | 3 | 0 | 3 |
| NELL1 | ITGB3 | 0.753438 | 3 | 0 | 3 |
| NELL1 | MGAT4C | 0.748379 | 3 | 0 | 3 |
| NELL1 | TINAGL1 | 0.748375 | 3 | 0 | 3 |
| NELL1 | MYH7 | 0.743079 | 3 | 0 | 3 |
| NELL1 | IKZF4 | 0.739252 | 3 | 0 | 3 |
| NELL1 | KAT7 | 0.738012 | 3 | 0 | 3 |
| NELL1 | BAGE | 0.736846 | 3 | 0 | 3 |
| NELL1 | LHX3 | 0.732971 | 3 | 0 | 3 |
| NELL1 | TP53I11 | 0.722636 | 3 | 0 | 3 |
| NELL1 | SETBP1 | 0.719724 | 3 | 0 | 3 |
| NELL1 | PTPN9 | 0.71896 | 3 | 0 | 3 |
| NELL1 | FIBCD1 | 0.717021 | 3 | 0 | 3 |
| NELL1 | CNKSR2 | 0.710264 | 3 | 0 | 3 |
| NELL1 | RAB11FIP3 | 0.709889 | 3 | 0 | 3 |
| NELL1 | TGFB2 | 0.704831 | 3 | 0 | 3 |
| NELL1 | RAB23 | 0.700289 | 3 | 0 | 3 |
| NELL1 | SOX17 | 0.699769 | 3 | 0 | 3 |
| NELL1 | MB | 0.699229 | 3 | 0 | 3 |
For details and further investigation, click here
