| Full name: ST18 C2H2C-type zinc finger transcription factor | Alias Symbol: KIAA0535|ZC2HC10|NZF3|NZF-3|ZC2H2C3 | ||
| Type: protein-coding gene | Cytoband: 8q11.23 | ||
| Entrez ID: 9705 | HGNC ID: HGNC:18695 | Ensembl Gene: ENSG00000147488 | OMIM ID: 617155 |
| Drug and gene relationship at DGIdb | |||
Expression of ST18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST18 | 9705 | 1570307_s_at | -0.2259 | 0.3714 | |
| GSE20347 | ST18 | 9705 | 206135_at | 0.0811 | 0.0894 | |
| GSE23400 | ST18 | 9705 | 206135_at | -0.0144 | 0.4410 | |
| GSE26886 | ST18 | 9705 | 1570307_s_at | 0.0018 | 0.9909 | |
| GSE29001 | ST18 | 9705 | 206135_at | 0.2007 | 0.3349 | |
| GSE38129 | ST18 | 9705 | 206135_at | 0.1225 | 0.4766 | |
| GSE45670 | ST18 | 9705 | 1570307_s_at | 0.0133 | 0.8960 | |
| GSE53622 | ST18 | 9705 | 104284 | 0.0924 | 0.5514 | |
| GSE53624 | ST18 | 9705 | 104284 | 0.1977 | 0.1883 | |
| GSE63941 | ST18 | 9705 | 1570307_s_at | 0.0843 | 0.5079 | |
| GSE77861 | ST18 | 9705 | 1570307_s_at | -0.0657 | 0.5252 | |
| SRP133303 | ST18 | 9705 | RNAseq | -0.0702 | 0.7425 | |
| SRP159526 | ST18 | 9705 | RNAseq | 0.2410 | 0.6913 | |
| SRP193095 | ST18 | 9705 | RNAseq | -0.1546 | 0.6148 | |
| TCGA | ST18 | 9705 | RNAseq | -1.9437 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ST18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST18 | 9705 | 15 | 2 | 13 | |
| GSE20123 | ST18 | 9705 | 15 | 2 | 13 | |
| GSE43470 | ST18 | 9705 | 14 | 3 | 26 | |
| GSE46452 | ST18 | 9705 | 21 | 3 | 35 | |
| GSE47630 | ST18 | 9705 | 23 | 1 | 16 | |
| GSE54993 | ST18 | 9705 | 1 | 16 | 53 | |
| GSE54994 | ST18 | 9705 | 28 | 0 | 25 | |
| GSE60625 | ST18 | 9705 | 0 | 4 | 7 | |
| GSE74703 | ST18 | 9705 | 13 | 2 | 21 | |
| GSE74704 | ST18 | 9705 | 11 | 0 | 9 | |
| TCGA | ST18 | 9705 | 43 | 10 | 43 |
Total number of gains: 184; Total number of losses: 43; Total Number of normals: 261.
Somatic mutations of ST18:
Generating mutation plots.
Highly correlated genes for ST18:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST18 | LINC00628 | 0.718253 | 3 | 0 | 3 |
| ST18 | RETN | 0.682336 | 3 | 0 | 3 |
| ST18 | LCN8 | 0.68105 | 3 | 0 | 3 |
| ST18 | PRM1 | 0.655958 | 3 | 0 | 3 |
| ST18 | BSND | 0.649675 | 3 | 0 | 3 |
| ST18 | MIR4755 | 0.645106 | 4 | 0 | 3 |
| ST18 | CAMK2B | 0.634801 | 3 | 0 | 3 |
| ST18 | TXNDC2 | 0.634671 | 5 | 0 | 4 |
| ST18 | SLC5A2 | 0.63331 | 3 | 0 | 3 |
| ST18 | GLRB | 0.632818 | 3 | 0 | 3 |
| ST18 | TMEM106A | 0.631193 | 4 | 0 | 3 |
| ST18 | LINC01231 | 0.624256 | 3 | 0 | 3 |
| ST18 | AVPR1A | 0.620509 | 3 | 0 | 3 |
| ST18 | ADCY1 | 0.617194 | 4 | 0 | 4 |
| ST18 | IQCJ-SCHIP1-AS1 | 0.616123 | 4 | 0 | 3 |
| ST18 | ULBP3 | 0.613369 | 3 | 0 | 3 |
| ST18 | KIF5C | 0.611699 | 5 | 0 | 4 |
| ST18 | DDC | 0.609167 | 3 | 0 | 3 |
| ST18 | NCR3 | 0.608863 | 3 | 0 | 3 |
| ST18 | LRTM2 | 0.607132 | 4 | 0 | 3 |
For details and further investigation, click here
