GOLPH3

 

Full name: golgi phosphoprotein 3 Alias Symbol: GPP34|GOPP1|MIDAS|Vps74
Type: protein-coding gene Cytoband: 5p13.3
Entrez ID: 64083 HGNC ID: HGNC:15452 Ensembl Gene: ENSG00000113384 OMIM ID: 612207
Drug and gene relationship at DGIdb

 

Expression of GOLPH3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GOLPH3 64083 217803_at 0.1466 0.7541
GSE20347 GOLPH3 64083 217803_at 0.1593 0.1400
GSE23400 GOLPH3 64083 217803_at 0.1431 0.0563
GSE26886 GOLPH3 64083 217803_at -0.0095 0.9682
GSE29001 GOLPH3 64083 217803_at -0.0135 0.9643
GSE38129 GOLPH3 64083 217803_at 0.0947 0.2767
GSE45670 GOLPH3 64083 217803_at 0.0351 0.8104
GSE53622 GOLPH3 64083 111789 0.0066 0.9331
GSE53624 GOLPH3 64083 111789 0.0371 0.5284
GSE63941 GOLPH3 64083 217803_at 0.0282 0.9412
GSE77861 GOLPH3 64083 217803_at 0.2557 0.3564
GSE97050 GOLPH3 64083 A_23_P156017 0.1094 0.6246
SRP007169 GOLPH3 64083 RNAseq -0.1026 0.7595
SRP008496 GOLPH3 64083 RNAseq 0.0253 0.9144
SRP064894 GOLPH3 64083 RNAseq -0.2201 0.3133
SRP133303 GOLPH3 64083 RNAseq 0.2387 0.2635
SRP159526 GOLPH3 64083 RNAseq 0.3282 0.2600
SRP193095 GOLPH3 64083 RNAseq -0.3420 0.0047
SRP219564 GOLPH3 64083 RNAseq -0.0827 0.8629
TCGA GOLPH3 64083 RNAseq -0.0496 0.2400

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GOLPH3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GOLPH3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GOLPH3 64083 11 0 19
GSE20123 GOLPH3 64083 11 0 19
GSE43470 GOLPH3 64083 15 3 25
GSE46452 GOLPH3 64083 6 21 32
GSE47630 GOLPH3 64083 6 12 22
GSE54993 GOLPH3 64083 5 4 61
GSE54994 GOLPH3 64083 27 2 24
GSE60625 GOLPH3 64083 0 0 11
GSE74703 GOLPH3 64083 12 2 22
GSE74704 GOLPH3 64083 10 0 10
TCGA GOLPH3 64083 51 6 39

Total number of gains: 154; Total number of losses: 50; Total Number of normals: 284.  


 

Somatic mutations of GOLPH3:

 

Generating mutation plots.

 

Highly correlated genes for GOLPH3:

 

Showing top 20/224 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GOLPH3KRR10.87683303
GOLPH3CCNT10.820133303
GOLPH3SCAI0.812148303
GOLPH3TUBE10.801694303
GOLPH3ZNF320.799371303
GOLPH3RRM2B0.779707303
GOLPH3BIVM0.771191303
GOLPH3RBPJ0.770731303
GOLPH3ZSCAN210.76846303
GOLPH3ERGIC20.755217303
GOLPH3ZNF5650.752425303
GOLPH3INTS100.749531303
GOLPH3TNKS0.74019303
GOLPH3HSF20.739428404
GOLPH3EIF3C0.736849303
GOLPH3AKAP17A0.736381303
GOLPH3NCOA50.735877303
GOLPH3RHEB0.732482303
GOLPH3ZNF4180.731662303
GOLPH3LYRM10.729037303

For details and further investigation, click here