| Full name: suppressor of cancer cell invasion | Alias Symbol: FLJ36664|NET40 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 286205 | HGNC ID: HGNC:26709 | Ensembl Gene: ENSG00000173611 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCAI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCAI | 286205 | 228174_at | 0.0849 | 0.9319 | |
| GSE20347 | SCAI | 286205 | 214997_at | 0.0011 | 0.9942 | |
| GSE23400 | SCAI | 286205 | 214997_at | 0.0747 | 0.0936 | |
| GSE26886 | SCAI | 286205 | 228174_at | 1.0313 | 0.0037 | |
| GSE29001 | SCAI | 286205 | 214997_at | 0.1197 | 0.6935 | |
| GSE38129 | SCAI | 286205 | 214997_at | -0.0054 | 0.9703 | |
| GSE45670 | SCAI | 286205 | 228174_at | -0.2395 | 0.3542 | |
| GSE53622 | SCAI | 286205 | 29893 | 0.0652 | 0.6145 | |
| GSE53624 | SCAI | 286205 | 87067 | -0.0630 | 0.5569 | |
| GSE63941 | SCAI | 286205 | 228174_at | 0.0527 | 0.9437 | |
| GSE77861 | SCAI | 286205 | 228174_at | 0.1962 | 0.3902 | |
| GSE97050 | SCAI | 286205 | A_23_P325625 | -0.2682 | 0.4033 | |
| SRP007169 | SCAI | 286205 | RNAseq | 0.6270 | 0.1363 | |
| SRP008496 | SCAI | 286205 | RNAseq | 0.5180 | 0.0343 | |
| SRP064894 | SCAI | 286205 | RNAseq | 0.2453 | 0.1942 | |
| SRP133303 | SCAI | 286205 | RNAseq | 0.0857 | 0.5374 | |
| SRP159526 | SCAI | 286205 | RNAseq | 0.3771 | 0.3228 | |
| SRP193095 | SCAI | 286205 | RNAseq | 0.0447 | 0.6658 | |
| SRP219564 | SCAI | 286205 | RNAseq | -0.1889 | 0.6024 | |
| TCGA | SCAI | 286205 | RNAseq | -0.0509 | 0.4965 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SCAI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCAI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCAI | 286205 | 4 | 8 | 18 | |
| GSE20123 | SCAI | 286205 | 4 | 8 | 18 | |
| GSE43470 | SCAI | 286205 | 6 | 4 | 33 | |
| GSE46452 | SCAI | 286205 | 6 | 13 | 40 | |
| GSE47630 | SCAI | 286205 | 3 | 16 | 21 | |
| GSE54993 | SCAI | 286205 | 3 | 3 | 64 | |
| GSE54994 | SCAI | 286205 | 12 | 8 | 33 | |
| GSE60625 | SCAI | 286205 | 0 | 0 | 11 | |
| GSE74703 | SCAI | 286205 | 5 | 3 | 28 | |
| GSE74704 | SCAI | 286205 | 2 | 6 | 12 | |
| TCGA | SCAI | 286205 | 27 | 25 | 44 |
Total number of gains: 72; Total number of losses: 94; Total Number of normals: 322.
Somatic mutations of SCAI:
Generating mutation plots.
Highly correlated genes for SCAI:
Showing top 20/540 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCAI | GOLPH3 | 0.812148 | 3 | 0 | 3 |
| SCAI | RICTOR | 0.806472 | 3 | 0 | 3 |
| SCAI | BOD1 | 0.793109 | 3 | 0 | 3 |
| SCAI | ARL5B | 0.756262 | 3 | 0 | 3 |
| SCAI | FAR2 | 0.754315 | 4 | 0 | 3 |
| SCAI | POLI | 0.750058 | 3 | 0 | 3 |
| SCAI | LRRC58 | 0.748029 | 3 | 0 | 3 |
| SCAI | KCNMB4 | 0.727422 | 4 | 0 | 3 |
| SCAI | GMPR | 0.726169 | 3 | 0 | 3 |
| SCAI | GPR158 | 0.725397 | 3 | 0 | 3 |
| SCAI | MTO1 | 0.721586 | 3 | 0 | 3 |
| SCAI | INTU | 0.71788 | 3 | 0 | 3 |
| SCAI | NBN | 0.716781 | 4 | 0 | 3 |
| SCAI | COA5 | 0.713779 | 4 | 0 | 3 |
| SCAI | ZSCAN21 | 0.711963 | 4 | 0 | 3 |
| SCAI | CPNE8 | 0.711055 | 3 | 0 | 3 |
| SCAI | APPBP2 | 0.708672 | 3 | 0 | 3 |
| SCAI | GNA13 | 0.701984 | 4 | 0 | 4 |
| SCAI | CDC42SE2 | 0.699763 | 3 | 0 | 3 |
| SCAI | MRPL24 | 0.698514 | 4 | 0 | 4 |
For details and further investigation, click here
