| Full name: KRR1 small subunit processome component homolog | Alias Symbol: RIP-1 | ||
| Type: protein-coding gene | Cytoband: 12q21.2 | ||
| Entrez ID: 11103 | HGNC ID: HGNC:5176 | Ensembl Gene: ENSG00000111615 | OMIM ID: 612817 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KRR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRR1 | 11103 | 203202_at | 0.0731 | 0.8647 | |
| GSE20347 | KRR1 | 11103 | 203203_s_at | 0.2589 | 0.0517 | |
| GSE23400 | KRR1 | 11103 | 203202_at | 0.2423 | 0.0119 | |
| GSE26886 | KRR1 | 11103 | 203202_at | -0.0432 | 0.8389 | |
| GSE29001 | KRR1 | 11103 | 203202_at | 0.2862 | 0.2754 | |
| GSE38129 | KRR1 | 11103 | 203202_at | 0.0007 | 0.9966 | |
| GSE45670 | KRR1 | 11103 | 203202_at | 0.1965 | 0.0707 | |
| GSE53622 | KRR1 | 11103 | 7035 | -0.3194 | 0.0000 | |
| GSE53624 | KRR1 | 11103 | 7035 | -0.0729 | 0.2447 | |
| GSE63941 | KRR1 | 11103 | 203202_at | -0.7150 | 0.2080 | |
| GSE77861 | KRR1 | 11103 | 203202_at | 0.4899 | 0.2358 | |
| GSE97050 | KRR1 | 11103 | A_32_P326819 | -0.2758 | 0.2733 | |
| SRP007169 | KRR1 | 11103 | RNAseq | 0.1776 | 0.6146 | |
| SRP008496 | KRR1 | 11103 | RNAseq | 0.4718 | 0.0215 | |
| SRP064894 | KRR1 | 11103 | RNAseq | 0.0040 | 0.9785 | |
| SRP133303 | KRR1 | 11103 | RNAseq | 0.2080 | 0.1332 | |
| SRP159526 | KRR1 | 11103 | RNAseq | 0.2942 | 0.2731 | |
| SRP193095 | KRR1 | 11103 | RNAseq | 0.0461 | 0.6580 | |
| SRP219564 | KRR1 | 11103 | RNAseq | -0.3375 | 0.2444 | |
| TCGA | KRR1 | 11103 | RNAseq | 0.1123 | 0.0269 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRR1 | 11103 | 3 | 3 | 24 | |
| GSE20123 | KRR1 | 11103 | 3 | 3 | 24 | |
| GSE43470 | KRR1 | 11103 | 3 | 0 | 40 | |
| GSE46452 | KRR1 | 11103 | 8 | 1 | 50 | |
| GSE47630 | KRR1 | 11103 | 10 | 1 | 29 | |
| GSE54993 | KRR1 | 11103 | 0 | 5 | 65 | |
| GSE54994 | KRR1 | 11103 | 5 | 2 | 46 | |
| GSE60625 | KRR1 | 11103 | 0 | 0 | 11 | |
| GSE74703 | KRR1 | 11103 | 3 | 0 | 33 | |
| GSE74704 | KRR1 | 11103 | 2 | 2 | 16 | |
| TCGA | KRR1 | 11103 | 14 | 15 | 67 |
Total number of gains: 51; Total number of losses: 32; Total Number of normals: 405.
Somatic mutations of KRR1:
Generating mutation plots.
Highly correlated genes for KRR1:
Showing top 20/366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRR1 | GOLPH3 | 0.87683 | 3 | 0 | 3 |
| KRR1 | ZSCAN21 | 0.808646 | 3 | 0 | 3 |
| KRR1 | PPIE | 0.773822 | 3 | 0 | 3 |
| KRR1 | PAIP1 | 0.767389 | 4 | 0 | 4 |
| KRR1 | METAP1D | 0.762312 | 3 | 0 | 3 |
| KRR1 | ZNF800 | 0.760995 | 3 | 0 | 3 |
| KRR1 | HSPB11 | 0.752128 | 3 | 0 | 3 |
| KRR1 | WDR70 | 0.747543 | 4 | 0 | 4 |
| KRR1 | BTAF1 | 0.745046 | 3 | 0 | 3 |
| KRR1 | ERI2 | 0.732823 | 3 | 0 | 3 |
| KRR1 | EIF5 | 0.730717 | 3 | 0 | 3 |
| KRR1 | MFN2 | 0.728686 | 3 | 0 | 3 |
| KRR1 | SNAPC3 | 0.72819 | 3 | 0 | 3 |
| KRR1 | GNA11 | 0.722425 | 3 | 0 | 3 |
| KRR1 | DNASE2 | 0.720205 | 3 | 0 | 3 |
| KRR1 | ZFR | 0.718483 | 5 | 0 | 4 |
| KRR1 | DNAJC13 | 0.717614 | 3 | 0 | 3 |
| KRR1 | DHX30 | 0.715491 | 3 | 0 | 3 |
| KRR1 | ASTE1 | 0.706683 | 3 | 0 | 3 |
| KRR1 | ZNF558 | 0.706045 | 3 | 0 | 3 |
For details and further investigation, click here
