GPR149

 

Full name: G protein-coupled receptor 149 Alias Symbol: PGR10|IEDA|R35
Type: protein-coding gene Cytoband: 3q25.2
Entrez ID: 344758 HGNC ID: HGNC:23627 Ensembl Gene: ENSG00000174948 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of GPR149:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 GPR149 344758 5366 0.8126 0.0000
GSE53624 GPR149 344758 5366 0.3872 0.0011
GSE97050 GPR149 344758 A_24_P332218 -0.2687 0.4159
SRP133303 GPR149 344758 RNAseq -0.1890 0.6032
TCGA GPR149 344758 RNAseq 0.7608 0.5055

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by GPR149 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GPR149:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GPR149 344758 21 1 8
GSE20123 GPR149 344758 21 1 8
GSE43470 GPR149 344758 23 0 20
GSE46452 GPR149 344758 18 2 39
GSE47630 GPR149 344758 19 3 18
GSE54993 GPR149 344758 1 10 59
GSE54994 GPR149 344758 38 1 14
GSE60625 GPR149 344758 0 6 5
GSE74703 GPR149 344758 20 0 16
GSE74704 GPR149 344758 14 0 6
TCGA GPR149 344758 73 1 22

Total number of gains: 248; Total number of losses: 25; Total Number of normals: 215.  

 

Somatic mutations of GPR149:

 

Generating mutation plots.

 

Highly correlated genes for GPR149:

 

Showing all 13 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GPR149CNTN60.760411303
GPR149SLC22A140.682336303
GPR149HDAC100.678877303
GPR149PGP0.662959303
GPR149HHATL0.65924303
GPR149SNED10.628462303
GPR149CCL250.60806303
GPR149TXNDC20.596597303
GPR149SHOX20.574275403
GPR149TRIM100.573051303
GPR149PVALB0.571341303
GPR149SP80.571011303
GPR149MMP190.500954403

For details and further investigation, click here