| Full name: C-C motif chemokine ligand 25 | Alias Symbol: TECK|Ckb15 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 6370 | HGNC ID: HGNC:10624 | Ensembl Gene: ENSG00000131142 | OMIM ID: 602565 |
| Drug and gene relationship at DGIdb | |||
CCL25 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04062 | Chemokine signaling pathway |
Expression of CCL25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCL25 | 6370 | 206988_at | -0.0353 | 0.9348 | |
| GSE20347 | CCL25 | 6370 | 206988_at | 0.0128 | 0.8693 | |
| GSE23400 | CCL25 | 6370 | 206988_at | -0.1757 | 0.0009 | |
| GSE26886 | CCL25 | 6370 | 206988_at | -0.0634 | 0.6181 | |
| GSE29001 | CCL25 | 6370 | 206988_at | -0.3178 | 0.0325 | |
| GSE38129 | CCL25 | 6370 | 206988_at | -0.0563 | 0.5863 | |
| GSE45670 | CCL25 | 6370 | 206988_at | 0.0787 | 0.4724 | |
| GSE53622 | CCL25 | 6370 | 36311 | 0.4891 | 0.0000 | |
| GSE53624 | CCL25 | 6370 | 36311 | 0.5155 | 0.0000 | |
| GSE63941 | CCL25 | 6370 | 206988_at | 0.4191 | 0.0286 | |
| GSE77861 | CCL25 | 6370 | 206988_at | -0.1354 | 0.4684 | |
| GSE97050 | CCL25 | 6370 | A_23_P55828 | 0.1299 | 0.6166 | |
| TCGA | CCL25 | 6370 | RNAseq | 1.4980 | 0.3386 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCL25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCL25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCL25 | 6370 | 4 | 3 | 23 | |
| GSE20123 | CCL25 | 6370 | 3 | 2 | 25 | |
| GSE43470 | CCL25 | 6370 | 2 | 7 | 34 | |
| GSE46452 | CCL25 | 6370 | 47 | 1 | 11 | |
| GSE47630 | CCL25 | 6370 | 5 | 7 | 28 | |
| GSE54993 | CCL25 | 6370 | 16 | 3 | 51 | |
| GSE54994 | CCL25 | 6370 | 6 | 14 | 33 | |
| GSE60625 | CCL25 | 6370 | 9 | 0 | 2 | |
| GSE74703 | CCL25 | 6370 | 2 | 4 | 30 | |
| GSE74704 | CCL25 | 6370 | 0 | 2 | 18 | |
| TCGA | CCL25 | 6370 | 10 | 20 | 66 |
Total number of gains: 104; Total number of losses: 63; Total Number of normals: 321.
Somatic mutations of CCL25:
Generating mutation plots.
Highly correlated genes for CCL25:
Showing top 20/1040 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCL25 | SPACA3 | 0.795597 | 3 | 0 | 3 |
| CCL25 | STRC | 0.769714 | 3 | 0 | 3 |
| CCL25 | C2CD4D | 0.767295 | 3 | 0 | 3 |
| CCL25 | LRRC10 | 0.757107 | 3 | 0 | 3 |
| CCL25 | TMEM179 | 0.751536 | 3 | 0 | 3 |
| CCL25 | DCDC1 | 0.742958 | 3 | 0 | 3 |
| CCL25 | RGL4 | 0.72588 | 3 | 0 | 3 |
| CCL25 | GPHB5 | 0.719297 | 3 | 0 | 3 |
| CCL25 | IQCF3 | 0.71835 | 3 | 0 | 3 |
| CCL25 | MCF2L | 0.716469 | 3 | 0 | 3 |
| CCL25 | ASB17 | 0.715263 | 3 | 0 | 3 |
| CCL25 | DEFB121 | 0.713861 | 5 | 0 | 5 |
| CCL25 | PGLYRP2 | 0.711254 | 4 | 0 | 3 |
| CCL25 | LHX9 | 0.708303 | 4 | 0 | 3 |
| CCL25 | PLA2G2C | 0.707691 | 3 | 0 | 3 |
| CCL25 | GRIK3 | 0.707469 | 6 | 0 | 6 |
| CCL25 | SLC6A5 | 0.706722 | 3 | 0 | 3 |
| CCL25 | LCE1D | 0.70609 | 3 | 0 | 3 |
| CCL25 | PABPN1L | 0.703031 | 3 | 0 | 3 |
| CCL25 | CBLN4 | 0.7028 | 4 | 0 | 4 |
For details and further investigation, click here
