| Full name: leucine rich repeats and IQ motif containing 3 | Alias Symbol: MGC22773 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 127255 | HGNC ID: HGNC:28318 | Ensembl Gene: ENSG00000162620 | OMIM ID: 617957 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRIQ3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRIQ3 | 127255 | 1553674_at | -0.0061 | 0.9862 | |
| GSE26886 | LRRIQ3 | 127255 | 1553674_at | -0.0867 | 0.3531 | |
| GSE45670 | LRRIQ3 | 127255 | 235498_at | 0.2320 | 0.3316 | |
| GSE53622 | LRRIQ3 | 127255 | 30750 | 0.0666 | 0.3777 | |
| GSE53624 | LRRIQ3 | 127255 | 30750 | 0.4518 | 0.0000 | |
| GSE63941 | LRRIQ3 | 127255 | 235498_at | 0.9678 | 0.2512 | |
| GSE77861 | LRRIQ3 | 127255 | 1553674_at | 0.0224 | 0.8411 | |
| GSE97050 | LRRIQ3 | 127255 | A_33_P3292402 | 0.1623 | 0.3977 | |
| TCGA | LRRIQ3 | 127255 | RNAseq | 0.3475 | 0.2877 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRIQ3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRIQ3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRIQ3 | 127255 | 1 | 7 | 22 | |
| GSE20123 | LRRIQ3 | 127255 | 1 | 7 | 22 | |
| GSE43470 | LRRIQ3 | 127255 | 4 | 2 | 37 | |
| GSE46452 | LRRIQ3 | 127255 | 0 | 1 | 58 | |
| GSE47630 | LRRIQ3 | 127255 | 8 | 6 | 26 | |
| GSE54993 | LRRIQ3 | 127255 | 0 | 0 | 70 | |
| GSE54994 | LRRIQ3 | 127255 | 6 | 4 | 43 | |
| GSE60625 | LRRIQ3 | 127255 | 0 | 0 | 11 | |
| GSE74703 | LRRIQ3 | 127255 | 3 | 2 | 31 | |
| GSE74704 | LRRIQ3 | 127255 | 1 | 4 | 15 | |
| TCGA | LRRIQ3 | 127255 | 8 | 24 | 64 |
Total number of gains: 32; Total number of losses: 57; Total Number of normals: 399.
Somatic mutations of LRRIQ3:
Generating mutation plots.
Highly correlated genes for LRRIQ3:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRIQ3 | OR5A1 | 0.813845 | 3 | 0 | 3 |
| LRRIQ3 | INSC | 0.793678 | 3 | 0 | 3 |
| LRRIQ3 | DEFB121 | 0.785654 | 3 | 0 | 3 |
| LRRIQ3 | TXNDC2 | 0.783004 | 3 | 0 | 3 |
| LRRIQ3 | OR2T1 | 0.766356 | 3 | 0 | 3 |
| LRRIQ3 | PABPN1L | 0.762124 | 3 | 0 | 3 |
| LRRIQ3 | GPR32 | 0.762035 | 3 | 0 | 3 |
| LRRIQ3 | TEX13A | 0.761323 | 3 | 0 | 3 |
| LRRIQ3 | LRIT1 | 0.757819 | 3 | 0 | 3 |
| LRRIQ3 | OR2T27 | 0.753552 | 3 | 0 | 3 |
| LRRIQ3 | MYH14 | 0.748514 | 3 | 0 | 3 |
| LRRIQ3 | DCDC1 | 0.746787 | 3 | 0 | 3 |
| LRRIQ3 | OR10A7 | 0.742929 | 3 | 0 | 3 |
| LRRIQ3 | BSX | 0.73519 | 3 | 0 | 3 |
| LRRIQ3 | PLA2G12B | 0.73491 | 3 | 0 | 3 |
| LRRIQ3 | GYPE | 0.732572 | 4 | 0 | 3 |
| LRRIQ3 | FOXB1 | 0.723295 | 3 | 0 | 3 |
| LRRIQ3 | PRKCG | 0.723004 | 3 | 0 | 3 |
| LRRIQ3 | OR2A12 | 0.721862 | 3 | 0 | 3 |
| LRRIQ3 | OR7G2 | 0.719931 | 3 | 0 | 3 |
For details and further investigation, click here
