| Full name: general transcription factor IIH subunit 5 | Alias Symbol: FLJ30544|bA120J8.2|TTD-A|TFB5|TFIIH|TTDA | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 404672 | HGNC ID: HGNC:21157 | Ensembl Gene: ENSG00000272047 | OMIM ID: 608780 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GTF2H5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2H5 | 404672 | 213357_at | -0.0570 | 0.9305 | |
| GSE20347 | GTF2H5 | 404672 | 213357_at | -0.2411 | 0.0649 | |
| GSE23400 | GTF2H5 | 404672 | 213357_at | -0.0016 | 0.9871 | |
| GSE26886 | GTF2H5 | 404672 | 213357_at | -0.8470 | 0.0003 | |
| GSE29001 | GTF2H5 | 404672 | 213357_at | -0.0632 | 0.8371 | |
| GSE38129 | GTF2H5 | 404672 | 213357_at | -0.2426 | 0.0324 | |
| GSE45670 | GTF2H5 | 404672 | 213357_at | -0.1175 | 0.3903 | |
| GSE53622 | GTF2H5 | 404672 | 70646 | -0.2289 | 0.0008 | |
| GSE53624 | GTF2H5 | 404672 | 70646 | -0.1268 | 0.0018 | |
| GSE63941 | GTF2H5 | 404672 | 213357_at | -0.7405 | 0.0560 | |
| GSE77861 | GTF2H5 | 404672 | 213357_at | -0.5132 | 0.1063 | |
| GSE97050 | GTF2H5 | 404672 | A_24_P196117 | -0.2417 | 0.2253 | |
| SRP007169 | GTF2H5 | 404672 | RNAseq | -0.6034 | 0.0706 | |
| SRP008496 | GTF2H5 | 404672 | RNAseq | -0.5471 | 0.0070 | |
| SRP064894 | GTF2H5 | 404672 | RNAseq | -0.1530 | 0.3592 | |
| SRP133303 | GTF2H5 | 404672 | RNAseq | -0.1098 | 0.4039 | |
| SRP159526 | GTF2H5 | 404672 | RNAseq | -0.4225 | 0.0145 | |
| SRP193095 | GTF2H5 | 404672 | RNAseq | -0.5952 | 0.0000 | |
| SRP219564 | GTF2H5 | 404672 | RNAseq | -0.5911 | 0.0932 | |
| TCGA | GTF2H5 | 404672 | RNAseq | -0.0779 | 0.2626 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2H5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2H5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2H5 | 404672 | 2 | 5 | 23 | |
| GSE20123 | GTF2H5 | 404672 | 2 | 4 | 24 | |
| GSE43470 | GTF2H5 | 404672 | 4 | 0 | 39 | |
| GSE46452 | GTF2H5 | 404672 | 3 | 10 | 46 | |
| GSE47630 | GTF2H5 | 404672 | 9 | 4 | 27 | |
| GSE54993 | GTF2H5 | 404672 | 3 | 2 | 65 | |
| GSE54994 | GTF2H5 | 404672 | 8 | 9 | 36 | |
| GSE60625 | GTF2H5 | 404672 | 0 | 1 | 10 | |
| GSE74703 | GTF2H5 | 404672 | 4 | 0 | 32 | |
| GSE74704 | GTF2H5 | 404672 | 0 | 2 | 18 | |
| TCGA | GTF2H5 | 404672 | 13 | 22 | 61 |
Total number of gains: 48; Total number of losses: 59; Total Number of normals: 381.
Somatic mutations of GTF2H5:
Generating mutation plots.
Highly correlated genes for GTF2H5:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2H5 | TOPORS | 0.860648 | 3 | 0 | 3 |
| GTF2H5 | ZSCAN16 | 0.790599 | 3 | 0 | 3 |
| GTF2H5 | ZNF124 | 0.768841 | 3 | 0 | 3 |
| GTF2H5 | TP53RK | 0.764351 | 3 | 0 | 3 |
| GTF2H5 | ANKRD17 | 0.758318 | 3 | 0 | 3 |
| GTF2H5 | PITRM1 | 0.756119 | 3 | 0 | 3 |
| GTF2H5 | CTDSPL | 0.755317 | 4 | 0 | 4 |
| GTF2H5 | ZNF273 | 0.748081 | 3 | 0 | 3 |
| GTF2H5 | SYTL4 | 0.7392 | 3 | 0 | 3 |
| GTF2H5 | C5orf51 | 0.73093 | 3 | 0 | 3 |
| GTF2H5 | CDC73 | 0.73023 | 3 | 0 | 3 |
| GTF2H5 | CBLL1 | 0.727205 | 3 | 0 | 3 |
| GTF2H5 | ZNF470 | 0.725211 | 3 | 0 | 3 |
| GTF2H5 | ZSCAN12 | 0.717306 | 3 | 0 | 3 |
| GTF2H5 | ZNF83 | 0.713972 | 5 | 0 | 4 |
| GTF2H5 | UBP1 | 0.713325 | 4 | 0 | 4 |
| GTF2H5 | CYP2C18 | 0.708355 | 3 | 0 | 3 |
| GTF2H5 | C15orf41 | 0.705722 | 3 | 0 | 3 |
| GTF2H5 | COG3 | 0.705715 | 3 | 0 | 3 |
| GTF2H5 | TRIM56 | 0.703761 | 3 | 0 | 3 |
For details and further investigation, click here
