| Full name: upstream binding protein 1 | Alias Symbol: LBP-1a | ||
| Type: protein-coding gene | Cytoband: 3p22.3 | ||
| Entrez ID: 7342 | HGNC ID: HGNC:12507 | Ensembl Gene: ENSG00000153560 | OMIM ID: 609784 |
| Drug and gene relationship at DGIdb | |||
Expression of UBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBP1 | 7342 | 218082_s_at | 0.2419 | 0.6112 | |
| GSE20347 | UBP1 | 7342 | 218082_s_at | -0.0355 | 0.8550 | |
| GSE23400 | UBP1 | 7342 | 218082_s_at | 0.3502 | 0.0000 | |
| GSE26886 | UBP1 | 7342 | 218082_s_at | -0.2361 | 0.1310 | |
| GSE29001 | UBP1 | 7342 | 218082_s_at | 0.1318 | 0.5265 | |
| GSE38129 | UBP1 | 7342 | 218082_s_at | -0.1495 | 0.2674 | |
| GSE45670 | UBP1 | 7342 | 218082_s_at | 0.0963 | 0.4533 | |
| GSE53622 | UBP1 | 7342 | 24896 | -0.2795 | 0.0000 | |
| GSE53624 | UBP1 | 7342 | 24896 | 0.0634 | 0.3320 | |
| GSE63941 | UBP1 | 7342 | 218082_s_at | -0.9359 | 0.0516 | |
| GSE77861 | UBP1 | 7342 | 218082_s_at | 0.0874 | 0.7080 | |
| GSE97050 | UBP1 | 7342 | A_23_P211738 | -0.4754 | 0.1247 | |
| SRP007169 | UBP1 | 7342 | RNAseq | 0.3158 | 0.3022 | |
| SRP008496 | UBP1 | 7342 | RNAseq | 0.6882 | 0.0012 | |
| SRP064894 | UBP1 | 7342 | RNAseq | 0.0115 | 0.9366 | |
| SRP133303 | UBP1 | 7342 | RNAseq | 0.0556 | 0.6433 | |
| SRP159526 | UBP1 | 7342 | RNAseq | -0.1812 | 0.4383 | |
| SRP193095 | UBP1 | 7342 | RNAseq | -0.0766 | 0.3440 | |
| SRP219564 | UBP1 | 7342 | RNAseq | -0.3978 | 0.1411 | |
| TCGA | UBP1 | 7342 | RNAseq | -0.1028 | 0.0211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBP1 | 7342 | 0 | 18 | 12 | |
| GSE20123 | UBP1 | 7342 | 0 | 18 | 12 | |
| GSE43470 | UBP1 | 7342 | 1 | 19 | 23 | |
| GSE46452 | UBP1 | 7342 | 2 | 17 | 40 | |
| GSE47630 | UBP1 | 7342 | 1 | 25 | 14 | |
| GSE54993 | UBP1 | 7342 | 6 | 3 | 61 | |
| GSE54994 | UBP1 | 7342 | 1 | 32 | 20 | |
| GSE60625 | UBP1 | 7342 | 5 | 0 | 6 | |
| GSE74703 | UBP1 | 7342 | 1 | 16 | 19 | |
| GSE74704 | UBP1 | 7342 | 0 | 12 | 8 | |
| TCGA | UBP1 | 7342 | 1 | 69 | 26 |
Total number of gains: 18; Total number of losses: 229; Total Number of normals: 241.
Somatic mutations of UBP1:
Generating mutation plots.
Highly correlated genes for UBP1:
Showing top 20/440 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBP1 | SKI | 0.847859 | 3 | 0 | 3 |
| UBP1 | MTCH2 | 0.775294 | 3 | 0 | 3 |
| UBP1 | MEX3C | 0.769078 | 3 | 0 | 3 |
| UBP1 | LRRC34 | 0.750817 | 3 | 0 | 3 |
| UBP1 | DHX40 | 0.741107 | 3 | 0 | 3 |
| UBP1 | BRWD1 | 0.731781 | 4 | 0 | 4 |
| UBP1 | NKIRAS1 | 0.729338 | 3 | 0 | 3 |
| UBP1 | CEP290 | 0.728393 | 3 | 0 | 3 |
| UBP1 | CLP1 | 0.726973 | 4 | 0 | 4 |
| UBP1 | THAP7 | 0.719149 | 3 | 0 | 3 |
| UBP1 | FAM122B | 0.714754 | 3 | 0 | 3 |
| UBP1 | GTF2H5 | 0.713325 | 4 | 0 | 4 |
| UBP1 | MFN2 | 0.711056 | 3 | 0 | 3 |
| UBP1 | BOLA1 | 0.710699 | 4 | 0 | 3 |
| UBP1 | ARHGAP24 | 0.706505 | 3 | 0 | 3 |
| UBP1 | PRICKLE2 | 0.703888 | 3 | 0 | 3 |
| UBP1 | YLPM1 | 0.703711 | 3 | 0 | 3 |
| UBP1 | KIF9 | 0.701406 | 3 | 0 | 3 |
| UBP1 | GPANK1 | 0.700403 | 3 | 0 | 3 |
| UBP1 | ZNF256 | 0.700137 | 4 | 0 | 3 |
For details and further investigation, click here
