| Full name: Cbl proto-oncogene like 1 | Alias Symbol: HAKAI|FLJ23109|RNF188 | ||
| Type: protein-coding gene | Cytoband: 7q22.3 | ||
| Entrez ID: 79872 | HGNC ID: HGNC:21225 | Ensembl Gene: ENSG00000105879 | OMIM ID: 606872 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CBLL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CBLL1 | 79872 | 227187_at | -0.3260 | 0.6132 | |
| GSE20347 | CBLL1 | 79872 | 220018_at | 0.6054 | 0.0045 | |
| GSE23400 | CBLL1 | 79872 | 220018_at | 0.1365 | 0.0010 | |
| GSE26886 | CBLL1 | 79872 | 227187_at | -0.3345 | 0.2661 | |
| GSE29001 | CBLL1 | 79872 | 220018_at | 0.5295 | 0.0652 | |
| GSE38129 | CBLL1 | 79872 | 220018_at | 0.6333 | 0.0000 | |
| GSE45670 | CBLL1 | 79872 | 227187_at | 0.1438 | 0.4286 | |
| GSE53622 | CBLL1 | 79872 | 152342 | 0.2773 | 0.0002 | |
| GSE53624 | CBLL1 | 79872 | 21343 | 0.0244 | 0.6767 | |
| GSE63941 | CBLL1 | 79872 | 227187_at | -0.6361 | 0.1764 | |
| GSE77861 | CBLL1 | 79872 | 227187_at | 0.0499 | 0.7733 | |
| GSE97050 | CBLL1 | 79872 | A_23_P146004 | -0.0909 | 0.7777 | |
| SRP007169 | CBLL1 | 79872 | RNAseq | 0.7466 | 0.0647 | |
| SRP008496 | CBLL1 | 79872 | RNAseq | 0.8008 | 0.0053 | |
| SRP064894 | CBLL1 | 79872 | RNAseq | -0.0726 | 0.5880 | |
| SRP133303 | CBLL1 | 79872 | RNAseq | 0.2041 | 0.1690 | |
| SRP159526 | CBLL1 | 79872 | RNAseq | 0.0144 | 0.9551 | |
| SRP193095 | CBLL1 | 79872 | RNAseq | 0.1618 | 0.1908 | |
| SRP219564 | CBLL1 | 79872 | RNAseq | -0.0148 | 0.9618 | |
| TCGA | CBLL1 | 79872 | RNAseq | 0.0135 | 0.7947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CBLL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CBLL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CBLL1 | 79872 | 12 | 0 | 18 | |
| GSE20123 | CBLL1 | 79872 | 12 | 0 | 18 | |
| GSE43470 | CBLL1 | 79872 | 6 | 2 | 35 | |
| GSE46452 | CBLL1 | 79872 | 10 | 1 | 48 | |
| GSE47630 | CBLL1 | 79872 | 8 | 3 | 29 | |
| GSE54993 | CBLL1 | 79872 | 2 | 9 | 59 | |
| GSE54994 | CBLL1 | 79872 | 16 | 3 | 34 | |
| GSE60625 | CBLL1 | 79872 | 0 | 0 | 11 | |
| GSE74703 | CBLL1 | 79872 | 6 | 2 | 28 | |
| GSE74704 | CBLL1 | 79872 | 8 | 0 | 12 | |
| TCGA | CBLL1 | 79872 | 50 | 10 | 36 |
Total number of gains: 130; Total number of losses: 30; Total Number of normals: 328.
Somatic mutations of CBLL1:
Generating mutation plots.
Highly correlated genes for CBLL1:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CBLL1 | ZNF33A | 0.840087 | 3 | 0 | 3 |
| CBLL1 | IMPACT | 0.831273 | 3 | 0 | 3 |
| CBLL1 | LARP7 | 0.819487 | 3 | 0 | 3 |
| CBLL1 | ZC3H13 | 0.815256 | 3 | 0 | 3 |
| CBLL1 | TMEM106B | 0.796132 | 3 | 0 | 3 |
| CBLL1 | LYRM1 | 0.792239 | 3 | 0 | 3 |
| CBLL1 | NAA30 | 0.785578 | 3 | 0 | 3 |
| CBLL1 | LSM11 | 0.77664 | 3 | 0 | 3 |
| CBLL1 | RAB11FIP2 | 0.773538 | 4 | 0 | 4 |
| CBLL1 | EIF3G | 0.770822 | 3 | 0 | 3 |
| CBLL1 | POLR3GL | 0.770659 | 3 | 0 | 3 |
| CBLL1 | TANC1 | 0.765542 | 3 | 0 | 3 |
| CBLL1 | CDKL3 | 0.763922 | 3 | 0 | 3 |
| CBLL1 | FBXL3 | 0.763312 | 3 | 0 | 3 |
| CBLL1 | EPC1 | 0.762189 | 3 | 0 | 3 |
| CBLL1 | ATP9A | 0.758756 | 3 | 0 | 3 |
| CBLL1 | HNRNPH3 | 0.758316 | 4 | 0 | 4 |
| CBLL1 | RNPC3 | 0.755159 | 3 | 0 | 3 |
| CBLL1 | POMZP3 | 0.753674 | 3 | 0 | 3 |
| CBLL1 | FAR2 | 0.751334 | 3 | 0 | 3 |
For details and further investigation, click here
