C15orf41

 

Full name: chromosome 15 open reading frame 41 Alias Symbol: HH114|MGC11326|FLJ22851
Type: protein-coding gene Cytoband: 15q14
Entrez ID: 84529 HGNC ID: HGNC:26929 Ensembl Gene: ENSG00000186073 OMIM ID: 615626
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of C15orf41:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C15orf41 84529 224486_s_at -0.6394 0.1630
GSE26886 C15orf41 84529 224486_s_at -0.6075 0.0002
GSE45670 C15orf41 84529 224486_s_at -0.4258 0.0117
GSE53622 C15orf41 84529 120360 -0.3290 0.0002
GSE53624 C15orf41 84529 120360 -0.5179 0.0000
GSE63941 C15orf41 84529 224486_s_at -0.0498 0.9525
GSE77861 C15orf41 84529 224486_s_at -0.2364 0.3049
GSE97050 C15orf41 84529 A_23_P77201 -0.8026 0.1133
SRP007169 C15orf41 84529 RNAseq -0.6435 0.1105
SRP008496 C15orf41 84529 RNAseq -0.7411 0.0141
SRP064894 C15orf41 84529 RNAseq -0.7819 0.0000
SRP133303 C15orf41 84529 RNAseq -0.4697 0.0247
SRP159526 C15orf41 84529 RNAseq -0.5589 0.1577
SRP193095 C15orf41 84529 RNAseq -0.7428 0.0000
SRP219564 C15orf41 84529 RNAseq -0.8182 0.0083
TCGA C15orf41 84529 RNAseq -0.0178 0.7809

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by C15orf41 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C15orf41:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C15orf41 84529 2 7 21
GSE20123 C15orf41 84529 2 7 21
GSE43470 C15orf41 84529 4 5 34
GSE46452 C15orf41 84529 3 7 49
GSE47630 C15orf41 84529 8 11 21
GSE54993 C15orf41 84529 4 6 60
GSE54994 C15orf41 84529 5 7 41
GSE60625 C15orf41 84529 4 0 7
GSE74703 C15orf41 84529 4 4 28
GSE74704 C15orf41 84529 1 6 13
TCGA C15orf41 84529 12 19 65

Total number of gains: 49; Total number of losses: 79; Total Number of normals: 360.  


 

Somatic mutations of C15orf41:

 

Generating mutation plots.

 

Highly correlated genes for C15orf41:

 

Showing top 20/770 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C15orf41CYYR10.818147303
C15orf41HMGCL0.810476303
C15orf41NCOR10.758333303
C15orf41ZFYVE10.751776303
C15orf41VPS26B0.745121303
C15orf41GSTK10.734591303
C15orf41MID20.726943303
C15orf41ARL2BP0.72386303
C15orf41SSBP30.714918404
C15orf41THSD7A0.714002303
C15orf41PRADC10.712703303
C15orf41KIAA05560.71121303
C15orf41UGP20.709153403
C15orf41CCDC1540.706302303
C15orf41GTF2H50.705722303
C15orf41CUL20.704392303
C15orf41MGST20.702388504
C15orf41EXD20.699123303
C15orf41C2CD20.699017303
C15orf41MIPEP0.697748504

For details and further investigation, click here