| Full name: glucuronidase beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q11.21 | ||
| Entrez ID: 2990 | HGNC ID: HGNC:4696 | Ensembl Gene: ENSG00000169919 | OMIM ID: 611499 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GUSB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GUSB | 2990 | 202605_at | 0.3498 | 0.3183 | |
| GSE20347 | GUSB | 2990 | 202605_at | 0.3440 | 0.1321 | |
| GSE23400 | GUSB | 2990 | 202605_at | 0.4875 | 0.0000 | |
| GSE26886 | GUSB | 2990 | 202605_at | 0.6220 | 0.0155 | |
| GSE29001 | GUSB | 2990 | 202605_at | 0.2652 | 0.5670 | |
| GSE38129 | GUSB | 2990 | 202605_at | 0.4402 | 0.0108 | |
| GSE45670 | GUSB | 2990 | 202605_at | 0.1351 | 0.4249 | |
| GSE53622 | GUSB | 2990 | 33308 | 0.1395 | 0.0664 | |
| GSE53624 | GUSB | 2990 | 33308 | 0.4148 | 0.0000 | |
| GSE63941 | GUSB | 2990 | 202605_at | 0.4640 | 0.3572 | |
| GSE77861 | GUSB | 2990 | 202605_at | 0.3069 | 0.2311 | |
| GSE97050 | GUSB | 2990 | A_23_P334608 | 0.3237 | 0.2268 | |
| SRP007169 | GUSB | 2990 | RNAseq | -0.5676 | 0.2093 | |
| SRP008496 | GUSB | 2990 | RNAseq | -0.5471 | 0.0458 | |
| SRP064894 | GUSB | 2990 | RNAseq | 0.6185 | 0.0120 | |
| SRP133303 | GUSB | 2990 | RNAseq | 0.2361 | 0.0713 | |
| SRP159526 | GUSB | 2990 | RNAseq | 0.3144 | 0.2307 | |
| SRP193095 | GUSB | 2990 | RNAseq | 0.0515 | 0.7125 | |
| SRP219564 | GUSB | 2990 | RNAseq | 0.4617 | 0.1243 | |
| TCGA | GUSB | 2990 | RNAseq | -0.0297 | 0.6577 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GUSB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GUSB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GUSB | 2990 | 11 | 2 | 17 | |
| GSE20123 | GUSB | 2990 | 10 | 2 | 18 | |
| GSE43470 | GUSB | 2990 | 2 | 1 | 40 | |
| GSE46452 | GUSB | 2990 | 13 | 0 | 46 | |
| GSE47630 | GUSB | 2990 | 7 | 1 | 32 | |
| GSE54993 | GUSB | 2990 | 2 | 7 | 61 | |
| GSE54994 | GUSB | 2990 | 12 | 4 | 37 | |
| GSE60625 | GUSB | 2990 | 0 | 0 | 11 | |
| GSE74703 | GUSB | 2990 | 2 | 1 | 33 | |
| GSE74704 | GUSB | 2990 | 5 | 1 | 14 | |
| TCGA | GUSB | 2990 | 47 | 6 | 43 |
Total number of gains: 111; Total number of losses: 25; Total Number of normals: 352.
Somatic mutations of GUSB:
Generating mutation plots.
Highly correlated genes for GUSB:
Showing top 20/788 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GUSB | RRP36 | 0.813476 | 3 | 0 | 3 |
| GUSB | FTSJ1 | 0.804024 | 3 | 0 | 3 |
| GUSB | C12orf73 | 0.80354 | 3 | 0 | 3 |
| GUSB | ZNF121 | 0.79616 | 3 | 0 | 3 |
| GUSB | SSBP4 | 0.792699 | 3 | 0 | 3 |
| GUSB | C10orf55 | 0.790301 | 3 | 0 | 3 |
| GUSB | NUDT19 | 0.789809 | 3 | 0 | 3 |
| GUSB | UBIAD1 | 0.781896 | 3 | 0 | 3 |
| GUSB | CHCHD6 | 0.780237 | 3 | 0 | 3 |
| GUSB | COMMD7 | 0.779722 | 3 | 0 | 3 |
| GUSB | PIGU | 0.775415 | 3 | 0 | 3 |
| GUSB | ACBD5 | 0.775098 | 3 | 0 | 3 |
| GUSB | APOO | 0.775046 | 3 | 0 | 3 |
| GUSB | LRRC58 | 0.769561 | 3 | 0 | 3 |
| GUSB | MEA1 | 0.768333 | 3 | 0 | 3 |
| GUSB | ARF3 | 0.766327 | 3 | 0 | 3 |
| GUSB | TSEN15 | 0.759411 | 3 | 0 | 3 |
| GUSB | PPIL1 | 0.754723 | 3 | 0 | 3 |
| GUSB | PHF20 | 0.752478 | 3 | 0 | 3 |
| GUSB | ANGEL2 | 0.746813 | 4 | 0 | 3 |
For details and further investigation, click here
