| Full name: ADP ribosylation factor 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 377 | HGNC ID: HGNC:654 | Ensembl Gene: ENSG00000134287 | OMIM ID: 103190 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARF3 | 377 | 200011_s_at | 0.2772 | 0.4017 | |
| GSE20347 | ARF3 | 377 | 200011_s_at | -0.1944 | 0.1709 | |
| GSE23400 | ARF3 | 377 | 200011_s_at | -0.0254 | 0.6758 | |
| GSE26886 | ARF3 | 377 | 200011_s_at | -0.8168 | 0.0004 | |
| GSE29001 | ARF3 | 377 | 200011_s_at | -0.0386 | 0.9131 | |
| GSE38129 | ARF3 | 377 | 200011_s_at | 0.0319 | 0.7902 | |
| GSE45670 | ARF3 | 377 | 200011_s_at | 0.1459 | 0.2726 | |
| GSE53622 | ARF3 | 377 | 69877 | 0.0201 | 0.7732 | |
| GSE53624 | ARF3 | 377 | 69877 | 0.0124 | 0.8379 | |
| GSE63941 | ARF3 | 377 | 200011_s_at | 0.9360 | 0.0056 | |
| GSE77861 | ARF3 | 377 | 200011_s_at | -0.0965 | 0.6007 | |
| GSE97050 | ARF3 | 377 | A_24_P256307 | 0.1678 | 0.4798 | |
| SRP007169 | ARF3 | 377 | RNAseq | -0.5799 | 0.0597 | |
| SRP008496 | ARF3 | 377 | RNAseq | -0.6248 | 0.0005 | |
| SRP064894 | ARF3 | 377 | RNAseq | 0.0189 | 0.8570 | |
| SRP133303 | ARF3 | 377 | RNAseq | 0.1850 | 0.2392 | |
| SRP159526 | ARF3 | 377 | RNAseq | 0.0780 | 0.6453 | |
| SRP193095 | ARF3 | 377 | RNAseq | -0.0164 | 0.8905 | |
| SRP219564 | ARF3 | 377 | RNAseq | 0.0731 | 0.8159 | |
| TCGA | ARF3 | 377 | RNAseq | 0.0114 | 0.7758 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARF3 | 377 | 6 | 1 | 23 | |
| GSE20123 | ARF3 | 377 | 6 | 1 | 23 | |
| GSE43470 | ARF3 | 377 | 4 | 1 | 38 | |
| GSE46452 | ARF3 | 377 | 8 | 1 | 50 | |
| GSE47630 | ARF3 | 377 | 11 | 2 | 27 | |
| GSE54993 | ARF3 | 377 | 0 | 5 | 65 | |
| GSE54994 | ARF3 | 377 | 4 | 1 | 48 | |
| GSE60625 | ARF3 | 377 | 0 | 0 | 11 | |
| GSE74703 | ARF3 | 377 | 4 | 1 | 31 | |
| GSE74704 | ARF3 | 377 | 4 | 1 | 15 | |
| TCGA | ARF3 | 377 | 16 | 13 | 67 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of ARF3:
Generating mutation plots.
Highly correlated genes for ARF3:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARF3 | NAA50 | 0.829024 | 3 | 0 | 3 |
| ARF3 | FBXW8 | 0.801377 | 3 | 0 | 3 |
| ARF3 | ELAVL1 | 0.776448 | 3 | 0 | 3 |
| ARF3 | GUSB | 0.766327 | 3 | 0 | 3 |
| ARF3 | RNFT2 | 0.760187 | 3 | 0 | 3 |
| ARF3 | PTPN6 | 0.757829 | 3 | 0 | 3 |
| ARF3 | SFPQ | 0.756929 | 3 | 0 | 3 |
| ARF3 | B9D2 | 0.747372 | 3 | 0 | 3 |
| ARF3 | USP22 | 0.73691 | 3 | 0 | 3 |
| ARF3 | MRPL18 | 0.728777 | 3 | 0 | 3 |
| ARF3 | IDH3G | 0.727849 | 3 | 0 | 3 |
| ARF3 | PDIK1L | 0.727529 | 3 | 0 | 3 |
| ARF3 | U2AF1 | 0.725433 | 3 | 0 | 3 |
| ARF3 | SLC35A4 | 0.723152 | 4 | 0 | 4 |
| ARF3 | SF3B4 | 0.713357 | 3 | 0 | 3 |
| ARF3 | USP54 | 0.712526 | 3 | 0 | 3 |
| ARF3 | DAZAP1 | 0.708392 | 3 | 0 | 3 |
| ARF3 | USP36 | 0.708035 | 3 | 0 | 3 |
| ARF3 | MRPS15 | 0.703932 | 3 | 0 | 3 |
| ARF3 | VPS39 | 0.703432 | 3 | 0 | 3 |
For details and further investigation, click here
