| Full name: male-enhanced antigen 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 4201 | HGNC ID: HGNC:6986 | Ensembl Gene: ENSG00000124733 | OMIM ID: 143170 |
| Drug and gene relationship at DGIdb | |||
Expression of MEA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEA1 | 4201 | 218061_at | 0.3648 | 0.4519 | |
| GSE20347 | MEA1 | 4201 | 218061_at | 0.2869 | 0.0346 | |
| GSE23400 | MEA1 | 4201 | 218061_at | 0.3912 | 0.0000 | |
| GSE26886 | MEA1 | 4201 | 218061_at | 1.0159 | 0.0000 | |
| GSE29001 | MEA1 | 4201 | 218061_at | 0.2920 | 0.2516 | |
| GSE38129 | MEA1 | 4201 | 218061_at | 0.3834 | 0.0001 | |
| GSE45670 | MEA1 | 4201 | 218061_at | 0.2222 | 0.0986 | |
| GSE53622 | MEA1 | 4201 | 21053 | 0.4230 | 0.0000 | |
| GSE53624 | MEA1 | 4201 | 21053 | 0.5937 | 0.0000 | |
| GSE63941 | MEA1 | 4201 | 218061_at | -0.1751 | 0.6300 | |
| GSE77861 | MEA1 | 4201 | 218061_at | -0.0376 | 0.9151 | |
| GSE97050 | MEA1 | 4201 | A_23_P30745 | 0.1795 | 0.4201 | |
| SRP007169 | MEA1 | 4201 | RNAseq | -0.4424 | 0.1792 | |
| SRP008496 | MEA1 | 4201 | RNAseq | -0.0800 | 0.7390 | |
| SRP064894 | MEA1 | 4201 | RNAseq | 0.4215 | 0.1409 | |
| SRP133303 | MEA1 | 4201 | RNAseq | 0.3349 | 0.0064 | |
| SRP159526 | MEA1 | 4201 | RNAseq | 0.3629 | 0.0414 | |
| SRP193095 | MEA1 | 4201 | RNAseq | -0.0143 | 0.9257 | |
| SRP219564 | MEA1 | 4201 | RNAseq | 0.2168 | 0.3565 | |
| TCGA | MEA1 | 4201 | RNAseq | 0.2147 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MEA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEA1 | 4201 | 7 | 0 | 23 | |
| GSE20123 | MEA1 | 4201 | 7 | 0 | 23 | |
| GSE43470 | MEA1 | 4201 | 6 | 0 | 37 | |
| GSE46452 | MEA1 | 4201 | 2 | 9 | 48 | |
| GSE47630 | MEA1 | 4201 | 8 | 4 | 28 | |
| GSE54993 | MEA1 | 4201 | 3 | 2 | 65 | |
| GSE54994 | MEA1 | 4201 | 11 | 4 | 38 | |
| GSE60625 | MEA1 | 4201 | 0 | 1 | 10 | |
| GSE74703 | MEA1 | 4201 | 6 | 0 | 30 | |
| GSE74704 | MEA1 | 4201 | 3 | 0 | 17 | |
| TCGA | MEA1 | 4201 | 21 | 13 | 62 |
Total number of gains: 74; Total number of losses: 33; Total Number of normals: 381.
Somatic mutations of MEA1:
Generating mutation plots.
Highly correlated genes for MEA1:
Showing top 20/1265 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEA1 | PACS1 | 0.864407 | 3 | 0 | 3 |
| MEA1 | CRTC2 | 0.84188 | 3 | 0 | 3 |
| MEA1 | ZNF766 | 0.839502 | 3 | 0 | 3 |
| MEA1 | PRR12 | 0.838118 | 3 | 0 | 3 |
| MEA1 | TBC1D25 | 0.818606 | 3 | 0 | 3 |
| MEA1 | RFNG | 0.804173 | 3 | 0 | 3 |
| MEA1 | ZFYVE27 | 0.801579 | 3 | 0 | 3 |
| MEA1 | ZNF121 | 0.788023 | 3 | 0 | 3 |
| MEA1 | C6orf136 | 0.786134 | 4 | 0 | 4 |
| MEA1 | ZNF805 | 0.781961 | 3 | 0 | 3 |
| MEA1 | GUSB | 0.768333 | 3 | 0 | 3 |
| MEA1 | ZNF579 | 0.76499 | 3 | 0 | 3 |
| MEA1 | MRPL36 | 0.760425 | 4 | 0 | 4 |
| MEA1 | UBA52 | 0.757256 | 4 | 0 | 4 |
| MEA1 | NAF1 | 0.755008 | 3 | 0 | 3 |
| MEA1 | THAP4 | 0.752486 | 3 | 0 | 3 |
| MEA1 | SSBP4 | 0.750629 | 4 | 0 | 3 |
| MEA1 | SP100 | 0.740342 | 3 | 0 | 3 |
| MEA1 | MED13 | 0.736837 | 3 | 0 | 3 |
| MEA1 | SLC35B2 | 0.733508 | 4 | 0 | 4 |
For details and further investigation, click here
