| Full name: phosphatidylinositol glycan anchor biosynthesis class U | Alias Symbol: bA346K17.2|GAB1 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 128869 | HGNC ID: HGNC:15791 | Ensembl Gene: ENSG00000101464 | OMIM ID: 608528 |
| Drug and gene relationship at DGIdb | |||
Expression of PIGU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGU | 128869 | 225903_at | 0.8088 | 0.0985 | |
| GSE26886 | PIGU | 128869 | 225903_at | -0.3535 | 0.2575 | |
| GSE45670 | PIGU | 128869 | 225903_at | 0.3844 | 0.0336 | |
| GSE53622 | PIGU | 128869 | 25290 | 0.6042 | 0.0000 | |
| GSE53624 | PIGU | 128869 | 25290 | 0.5449 | 0.0000 | |
| GSE63941 | PIGU | 128869 | 225903_at | 0.9911 | 0.0462 | |
| GSE77861 | PIGU | 128869 | 225903_at | 0.4294 | 0.0197 | |
| GSE97050 | PIGU | 128869 | A_33_P3769406 | 0.4013 | 0.2630 | |
| SRP007169 | PIGU | 128869 | RNAseq | -0.3770 | 0.3580 | |
| SRP008496 | PIGU | 128869 | RNAseq | -0.1384 | 0.6170 | |
| SRP064894 | PIGU | 128869 | RNAseq | 0.8325 | 0.0022 | |
| SRP133303 | PIGU | 128869 | RNAseq | 0.4234 | 0.0009 | |
| SRP159526 | PIGU | 128869 | RNAseq | 0.1927 | 0.5616 | |
| SRP193095 | PIGU | 128869 | RNAseq | 0.0694 | 0.5493 | |
| SRP219564 | PIGU | 128869 | RNAseq | 0.6179 | 0.0085 | |
| TCGA | PIGU | 128869 | RNAseq | 0.2848 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIGU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGU | 128869 | 16 | 0 | 14 | |
| GSE20123 | PIGU | 128869 | 16 | 0 | 14 | |
| GSE43470 | PIGU | 128869 | 12 | 0 | 31 | |
| GSE46452 | PIGU | 128869 | 29 | 0 | 30 | |
| GSE47630 | PIGU | 128869 | 24 | 1 | 15 | |
| GSE54993 | PIGU | 128869 | 0 | 18 | 52 | |
| GSE54994 | PIGU | 128869 | 25 | 1 | 27 | |
| GSE60625 | PIGU | 128869 | 0 | 0 | 11 | |
| GSE74703 | PIGU | 128869 | 11 | 0 | 25 | |
| GSE74704 | PIGU | 128869 | 11 | 0 | 9 | |
| TCGA | PIGU | 128869 | 50 | 2 | 44 |
Total number of gains: 194; Total number of losses: 22; Total Number of normals: 272.
Somatic mutations of PIGU:
Generating mutation plots.
Highly correlated genes for PIGU:
Showing top 20/1085 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGU | MCAT | 0.843505 | 3 | 0 | 3 |
| PIGU | CHD4 | 0.830891 | 3 | 0 | 3 |
| PIGU | MOB3C | 0.7932 | 3 | 0 | 3 |
| PIGU | C12orf73 | 0.776965 | 3 | 0 | 3 |
| PIGU | GUSB | 0.775415 | 3 | 0 | 3 |
| PIGU | MCMBP | 0.769224 | 3 | 0 | 3 |
| PIGU | U2AF1 | 0.765895 | 3 | 0 | 3 |
| PIGU | SPTSSA | 0.762724 | 3 | 0 | 3 |
| PIGU | TMEM179B | 0.762539 | 3 | 0 | 3 |
| PIGU | MRPL38 | 0.761115 | 3 | 0 | 3 |
| PIGU | NUP153 | 0.759561 | 3 | 0 | 3 |
| PIGU | RBMX2 | 0.757787 | 3 | 0 | 3 |
| PIGU | CLSTN1 | 0.753813 | 3 | 0 | 3 |
| PIGU | RALGAPB | 0.753378 | 5 | 0 | 5 |
| PIGU | PLAGL2 | 0.751126 | 5 | 0 | 4 |
| PIGU | TUBA1B | 0.748992 | 3 | 0 | 3 |
| PIGU | KLHL8 | 0.747577 | 3 | 0 | 3 |
| PIGU | HSPB11 | 0.74248 | 3 | 0 | 3 |
| PIGU | DYRK2 | 0.738472 | 3 | 0 | 3 |
| PIGU | CENPBD1 | 0.738375 | 3 | 0 | 3 |
For details and further investigation, click here
