ANGEL2

 

Full name: angel homolog 2 Alias Symbol: KIAA0759L|FLJ12793|Ccr4d
Type: protein-coding gene Cytoband: 1q32.3
Entrez ID: 90806 HGNC ID: HGNC:30534 Ensembl Gene: ENSG00000174606 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ANGEL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ANGEL2 90806 221825_at 0.1942 0.5985
GSE20347 ANGEL2 90806 221825_at 0.1290 0.4883
GSE23400 ANGEL2 90806 221825_at 0.2055 0.0389
GSE26886 ANGEL2 90806 221825_at 0.3928 0.2596
GSE29001 ANGEL2 90806 221825_at 0.1846 0.5898
GSE38129 ANGEL2 90806 221825_at 0.0596 0.6936
GSE45670 ANGEL2 90806 221825_at -0.2592 0.0961
GSE53622 ANGEL2 90806 64794 0.3899 0.0000
GSE53624 ANGEL2 90806 98640 0.0821 0.2354
GSE63941 ANGEL2 90806 221825_at -0.4293 0.5752
GSE77861 ANGEL2 90806 221825_at 0.3725 0.1680
GSE97050 ANGEL2 90806 A_23_P343237 0.1664 0.5183
SRP007169 ANGEL2 90806 RNAseq 0.2226 0.5611
SRP008496 ANGEL2 90806 RNAseq 0.5963 0.0460
SRP064894 ANGEL2 90806 RNAseq 0.1882 0.2752
SRP133303 ANGEL2 90806 RNAseq 0.2191 0.1522
SRP159526 ANGEL2 90806 RNAseq 0.3489 0.1038
SRP193095 ANGEL2 90806 RNAseq 0.0644 0.4398
SRP219564 ANGEL2 90806 RNAseq 0.2585 0.4400
TCGA ANGEL2 90806 RNAseq -0.0279 0.6272

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ANGEL2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ANGEL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ANGEL2 90806 9 0 21
GSE20123 ANGEL2 90806 9 0 21
GSE43470 ANGEL2 90806 7 1 35
GSE46452 ANGEL2 90806 3 1 55
GSE47630 ANGEL2 90806 15 0 25
GSE54993 ANGEL2 90806 0 6 64
GSE54994 ANGEL2 90806 13 0 40
GSE60625 ANGEL2 90806 0 0 11
GSE74703 ANGEL2 90806 7 1 28
GSE74704 ANGEL2 90806 3 0 17
TCGA ANGEL2 90806 46 3 47

Total number of gains: 112; Total number of losses: 12; Total Number of normals: 364.  

 

Somatic mutations of ANGEL2:

 

Generating mutation plots.

 

Highly correlated genes for ANGEL2:

 

Showing top 20/808 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ANGEL2PLEKHF20.791876303
ANGEL2CEP440.778771303
ANGEL2ERP270.774483303
ANGEL2PCGF60.754635303
ANGEL2ZFYVE270.752204404
ANGEL2PET1170.749862303
ANGEL2ANAPC40.749358303
ANGEL2CRLS10.748067303
ANGEL2GUSB0.746813403
ANGEL2ZNF2660.744885303
ANGEL2LRRC340.741438303
ANGEL2ESCO10.740709303
ANGEL2NSUN30.737764303
ANGEL2LRRC580.731505303
ANGEL2EIF2AK40.725713403
ANGEL2SMAD10.725263303
ANGEL2SPICE10.720743303
ANGEL2METAP1D0.719631303
ANGEL2SBNO10.719011505
ANGEL2RCL10.715958303

For details and further investigation, click here