| Full name: chromosome 12 open reading frame 73 | Alias Symbol: FLJ13975|DKFZp547P055 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 728568 | HGNC ID: HGNC:34450 | Ensembl Gene: ENSG00000204954 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf73:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf73 | 728568 | 226943_at | 0.7256 | 0.1070 | |
| GSE26886 | C12orf73 | 728568 | 226927_at | 0.4654 | 0.0335 | |
| GSE45670 | C12orf73 | 728568 | 226943_at | 0.4760 | 0.0051 | |
| GSE53622 | C12orf73 | 728568 | 126000 | -0.1545 | 0.3763 | |
| GSE53624 | C12orf73 | 728568 | 35614 | 0.1224 | 0.3138 | |
| GSE63941 | C12orf73 | 728568 | 226943_at | 0.9087 | 0.0477 | |
| GSE77861 | C12orf73 | 728568 | 226927_at | -0.0174 | 0.9286 | |
| GSE97050 | C12orf73 | 728568 | A_24_P769672 | 0.1745 | 0.3883 | |
| SRP007169 | C12orf73 | 728568 | RNAseq | 1.0980 | 0.0646 | |
| SRP008496 | C12orf73 | 728568 | RNAseq | 0.6440 | 0.1025 | |
| SRP064894 | C12orf73 | 728568 | RNAseq | 0.4585 | 0.0331 | |
| SRP133303 | C12orf73 | 728568 | RNAseq | 0.5167 | 0.0192 | |
| SRP159526 | C12orf73 | 728568 | RNAseq | 0.7717 | 0.0047 | |
| SRP193095 | C12orf73 | 728568 | RNAseq | 0.1966 | 0.0487 | |
| SRP219564 | C12orf73 | 728568 | RNAseq | 0.3459 | 0.4533 | |
| TCGA | C12orf73 | 728568 | RNAseq | 0.0371 | 0.6303 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C12orf73 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf73:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf73 | 728568 | 4 | 2 | 24 | |
| GSE20123 | C12orf73 | 728568 | 4 | 2 | 24 | |
| GSE43470 | C12orf73 | 728568 | 2 | 0 | 41 | |
| GSE46452 | C12orf73 | 728568 | 9 | 1 | 49 | |
| GSE47630 | C12orf73 | 728568 | 9 | 1 | 30 | |
| GSE54993 | C12orf73 | 728568 | 0 | 5 | 65 | |
| GSE54994 | C12orf73 | 728568 | 4 | 2 | 47 | |
| GSE60625 | C12orf73 | 728568 | 0 | 0 | 11 | |
| GSE74703 | C12orf73 | 728568 | 2 | 0 | 34 | |
| GSE74704 | C12orf73 | 728568 | 1 | 2 | 17 | |
| TCGA | C12orf73 | 728568 | 19 | 11 | 66 |
Total number of gains: 54; Total number of losses: 26; Total Number of normals: 408.
Somatic mutations of C12orf73:
Generating mutation plots.
Highly correlated genes for C12orf73:
Showing top 20/751 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf73 | ZNF551 | 0.807234 | 3 | 0 | 3 |
| C12orf73 | GUSB | 0.80354 | 3 | 0 | 3 |
| C12orf73 | HNRNPM | 0.794431 | 3 | 0 | 3 |
| C12orf73 | LEMD2 | 0.793614 | 3 | 0 | 3 |
| C12orf73 | EHMT2 | 0.793161 | 3 | 0 | 3 |
| C12orf73 | LRRC58 | 0.79037 | 4 | 0 | 4 |
| C12orf73 | DYRK2 | 0.786263 | 3 | 0 | 3 |
| C12orf73 | BPNT1 | 0.783612 | 3 | 0 | 3 |
| C12orf73 | CHD4 | 0.783505 | 3 | 0 | 3 |
| C12orf73 | POLR2B | 0.782524 | 3 | 0 | 3 |
| C12orf73 | PIGU | 0.776965 | 3 | 0 | 3 |
| C12orf73 | SNX30 | 0.773447 | 3 | 0 | 3 |
| C12orf73 | PRCC | 0.770893 | 3 | 0 | 3 |
| C12orf73 | PIF1 | 0.770362 | 3 | 0 | 3 |
| C12orf73 | RHBDD2 | 0.769418 | 3 | 0 | 3 |
| C12orf73 | UBR7 | 0.769375 | 3 | 0 | 3 |
| C12orf73 | ZBTB9 | 0.768464 | 3 | 0 | 3 |
| C12orf73 | GLRX3 | 0.764891 | 3 | 0 | 3 |
| C12orf73 | PSMB1 | 0.763651 | 3 | 0 | 3 |
| C12orf73 | NCBP2 | 0.761542 | 3 | 0 | 3 |
For details and further investigation, click here
