| Full name: PHD finger protein 20 | Alias Symbol: dJ1121G12.1|TDRD20A | ||
| Type: protein-coding gene | Cytoband: 20q11.22-q11.23 | ||
| Entrez ID: 51230 | HGNC ID: HGNC:16098 | Ensembl Gene: ENSG00000025293 | OMIM ID: 610335 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF20 | 51230 | 209422_at | 0.0570 | 0.9454 | |
| GSE20347 | PHF20 | 51230 | 209422_at | -0.0346 | 0.7971 | |
| GSE23400 | PHF20 | 51230 | 206567_s_at | 0.0341 | 0.6688 | |
| GSE26886 | PHF20 | 51230 | 209422_at | 1.1547 | 0.0000 | |
| GSE29001 | PHF20 | 51230 | 209422_at | 0.0043 | 0.9878 | |
| GSE38129 | PHF20 | 51230 | 209422_at | -0.0572 | 0.7226 | |
| GSE45670 | PHF20 | 51230 | 209422_at | -0.4699 | 0.0048 | |
| GSE53622 | PHF20 | 51230 | 6363 | 0.0818 | 0.2464 | |
| GSE53624 | PHF20 | 51230 | 6363 | 0.0586 | 0.4480 | |
| GSE63941 | PHF20 | 51230 | 209422_at | -0.0085 | 0.9871 | |
| GSE77861 | PHF20 | 51230 | 209422_at | -0.0970 | 0.7778 | |
| GSE97050 | PHF20 | 51230 | A_24_P181944 | 0.0501 | 0.8776 | |
| SRP007169 | PHF20 | 51230 | RNAseq | 0.4057 | 0.2243 | |
| SRP008496 | PHF20 | 51230 | RNAseq | 0.5217 | 0.0182 | |
| SRP064894 | PHF20 | 51230 | RNAseq | 0.0542 | 0.7590 | |
| SRP133303 | PHF20 | 51230 | RNAseq | 0.2711 | 0.0793 | |
| SRP159526 | PHF20 | 51230 | RNAseq | -0.2200 | 0.3909 | |
| SRP193095 | PHF20 | 51230 | RNAseq | 0.1399 | 0.2081 | |
| SRP219564 | PHF20 | 51230 | RNAseq | 0.2258 | 0.4491 | |
| TCGA | PHF20 | 51230 | RNAseq | -0.0720 | 0.1534 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PHF20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF20 | 51230 | 15 | 1 | 14 | |
| GSE20123 | PHF20 | 51230 | 15 | 1 | 14 | |
| GSE43470 | PHF20 | 51230 | 12 | 0 | 31 | |
| GSE46452 | PHF20 | 51230 | 29 | 0 | 30 | |
| GSE47630 | PHF20 | 51230 | 25 | 0 | 15 | |
| GSE54993 | PHF20 | 51230 | 0 | 17 | 53 | |
| GSE54994 | PHF20 | 51230 | 24 | 0 | 29 | |
| GSE60625 | PHF20 | 51230 | 0 | 0 | 11 | |
| GSE74703 | PHF20 | 51230 | 11 | 0 | 25 | |
| GSE74704 | PHF20 | 51230 | 11 | 0 | 9 | |
| TCGA | PHF20 | 51230 | 49 | 3 | 44 |
Total number of gains: 191; Total number of losses: 22; Total Number of normals: 275.
Somatic mutations of PHF20:
Generating mutation plots.
Highly correlated genes for PHF20:
Showing top 20/362 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF20 | EBAG9 | 0.839868 | 3 | 0 | 3 |
| PHF20 | THEM4 | 0.839294 | 3 | 0 | 3 |
| PHF20 | LRCH3 | 0.794107 | 3 | 0 | 3 |
| PHF20 | ARID2 | 0.776059 | 3 | 0 | 3 |
| PHF20 | KIF16B | 0.775824 | 3 | 0 | 3 |
| PHF20 | NAP1L1 | 0.768007 | 3 | 0 | 3 |
| PHF20 | LRRCC1 | 0.764013 | 4 | 0 | 4 |
| PHF20 | PHIP | 0.75981 | 3 | 0 | 3 |
| PHF20 | PPWD1 | 0.757749 | 3 | 0 | 3 |
| PHF20 | GUSB | 0.752478 | 3 | 0 | 3 |
| PHF20 | CLCC1 | 0.752383 | 3 | 0 | 3 |
| PHF20 | PROCR | 0.749249 | 3 | 0 | 3 |
| PHF20 | DHX40 | 0.74616 | 3 | 0 | 3 |
| PHF20 | ZNF805 | 0.745616 | 3 | 0 | 3 |
| PHF20 | CDK8 | 0.736617 | 3 | 0 | 3 |
| PHF20 | FAM171B | 0.735475 | 3 | 0 | 3 |
| PHF20 | ROMO1 | 0.731408 | 3 | 0 | 3 |
| PHF20 | RPS21 | 0.730015 | 4 | 0 | 4 |
| PHF20 | TSEN34 | 0.728995 | 3 | 0 | 3 |
| PHF20 | HSDL1 | 0.716995 | 3 | 0 | 3 |
For details and further investigation, click here
