| Full name: hydroxyacylglutathione hydrolase | Alias Symbol: GLO2|GLXII|HAGH1 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 3029 | HGNC ID: HGNC:4805 | Ensembl Gene: ENSG00000063854 | OMIM ID: 138760 |
| Drug and gene relationship at DGIdb | |||
Expression of HAGH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAGH | 3029 | 205012_s_at | -0.2489 | 0.4570 | |
| GSE20347 | HAGH | 3029 | 205012_s_at | -0.2541 | 0.0563 | |
| GSE23400 | HAGH | 3029 | 205012_s_at | -0.0573 | 0.3448 | |
| GSE26886 | HAGH | 3029 | 205012_s_at | 0.3231 | 0.0465 | |
| GSE29001 | HAGH | 3029 | 205012_s_at | -0.0507 | 0.8737 | |
| GSE38129 | HAGH | 3029 | 205012_s_at | -0.2567 | 0.0850 | |
| GSE45670 | HAGH | 3029 | 205012_s_at | -0.0631 | 0.6525 | |
| GSE53622 | HAGH | 3029 | 124463 | -0.5153 | 0.0000 | |
| GSE53624 | HAGH | 3029 | 124463 | -0.3714 | 0.0000 | |
| GSE63941 | HAGH | 3029 | 205012_s_at | -0.2467 | 0.5292 | |
| GSE77861 | HAGH | 3029 | 205012_s_at | 0.0728 | 0.7331 | |
| GSE97050 | HAGH | 3029 | A_33_P3333488 | -0.4654 | 0.1887 | |
| SRP007169 | HAGH | 3029 | RNAseq | -0.6092 | 0.2873 | |
| SRP064894 | HAGH | 3029 | RNAseq | -0.0297 | 0.9033 | |
| SRP133303 | HAGH | 3029 | RNAseq | 0.1254 | 0.5497 | |
| SRP159526 | HAGH | 3029 | RNAseq | -0.0162 | 0.9588 | |
| SRP193095 | HAGH | 3029 | RNAseq | -0.2864 | 0.0209 | |
| SRP219564 | HAGH | 3029 | RNAseq | -0.3528 | 0.4169 | |
| TCGA | HAGH | 3029 | RNAseq | -0.2422 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HAGH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAGH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAGH | 3029 | 5 | 5 | 20 | |
| GSE20123 | HAGH | 3029 | 5 | 4 | 21 | |
| GSE43470 | HAGH | 3029 | 4 | 7 | 32 | |
| GSE46452 | HAGH | 3029 | 38 | 1 | 20 | |
| GSE47630 | HAGH | 3029 | 13 | 6 | 21 | |
| GSE54993 | HAGH | 3029 | 3 | 5 | 62 | |
| GSE54994 | HAGH | 3029 | 6 | 8 | 39 | |
| GSE60625 | HAGH | 3029 | 4 | 0 | 7 | |
| GSE74703 | HAGH | 3029 | 4 | 5 | 27 | |
| GSE74704 | HAGH | 3029 | 3 | 2 | 15 | |
| TCGA | HAGH | 3029 | 19 | 14 | 63 |
Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.
Somatic mutations of HAGH:
Generating mutation plots.
Highly correlated genes for HAGH:
Showing top 20/361 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAGH | CLMP | 0.80367 | 3 | 0 | 3 |
| HAGH | OLFML1 | 0.780563 | 3 | 0 | 3 |
| HAGH | ZFAND2A | 0.777786 | 3 | 0 | 3 |
| HAGH | NKIRAS1 | 0.773604 | 3 | 0 | 3 |
| HAGH | CBR4 | 0.773151 | 3 | 0 | 3 |
| HAGH | BBS9 | 0.769181 | 3 | 0 | 3 |
| HAGH | PTPRM | 0.764195 | 3 | 0 | 3 |
| HAGH | HSPA12A | 0.756289 | 3 | 0 | 3 |
| HAGH | KCNJ8 | 0.750482 | 3 | 0 | 3 |
| HAGH | CHADL | 0.738746 | 3 | 0 | 3 |
| HAGH | UBXN10 | 0.735977 | 3 | 0 | 3 |
| HAGH | SPTBN1 | 0.733996 | 3 | 0 | 3 |
| HAGH | RPS19BP1 | 0.728732 | 3 | 0 | 3 |
| HAGH | LEPROT | 0.727499 | 3 | 0 | 3 |
| HAGH | ZNF334 | 0.726623 | 3 | 0 | 3 |
| HAGH | KIAA1191 | 0.72576 | 3 | 0 | 3 |
| HAGH | RASD2 | 0.725374 | 3 | 0 | 3 |
| HAGH | PCNP | 0.721035 | 3 | 0 | 3 |
| HAGH | FBLN5 | 0.717755 | 3 | 0 | 3 |
| HAGH | CDKN1C | 0.715311 | 3 | 0 | 3 |
For details and further investigation, click here
