| Full name: ribosomal protein S19 binding protein 1 | Alias Symbol: MGC52010|FLJ21770 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 91582 | HGNC ID: HGNC:28749 | Ensembl Gene: ENSG00000187051 | OMIM ID: 610225 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPS19BP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS19BP1 | 91582 | 225148_at | 0.1824 | 0.5841 | |
| GSE26886 | RPS19BP1 | 91582 | 225148_at | 0.9082 | 0.0000 | |
| GSE45670 | RPS19BP1 | 91582 | 225148_at | 0.1234 | 0.3778 | |
| GSE53622 | RPS19BP1 | 91582 | 27319 | -0.0022 | 0.9816 | |
| GSE53624 | RPS19BP1 | 91582 | 27319 | 0.1323 | 0.0614 | |
| GSE63941 | RPS19BP1 | 91582 | 225148_at | -0.4745 | 0.2587 | |
| GSE77861 | RPS19BP1 | 91582 | 225148_at | 0.1984 | 0.3702 | |
| GSE97050 | RPS19BP1 | 91582 | A_24_P740705 | -0.2826 | 0.2488 | |
| SRP007169 | RPS19BP1 | 91582 | RNAseq | -0.3523 | 0.3547 | |
| SRP008496 | RPS19BP1 | 91582 | RNAseq | -0.4925 | 0.0280 | |
| SRP064894 | RPS19BP1 | 91582 | RNAseq | 0.6004 | 0.1362 | |
| SRP133303 | RPS19BP1 | 91582 | RNAseq | 0.2126 | 0.2124 | |
| SRP159526 | RPS19BP1 | 91582 | RNAseq | 0.3699 | 0.0842 | |
| SRP193095 | RPS19BP1 | 91582 | RNAseq | -0.2058 | 0.0982 | |
| SRP219564 | RPS19BP1 | 91582 | RNAseq | 0.0094 | 0.9785 | |
| TCGA | RPS19BP1 | 91582 | RNAseq | -0.0482 | 0.3658 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPS19BP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS19BP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS19BP1 | 91582 | 6 | 5 | 19 | |
| GSE20123 | RPS19BP1 | 91582 | 6 | 4 | 20 | |
| GSE43470 | RPS19BP1 | 91582 | 5 | 6 | 32 | |
| GSE46452 | RPS19BP1 | 91582 | 32 | 2 | 25 | |
| GSE47630 | RPS19BP1 | 91582 | 9 | 4 | 27 | |
| GSE54993 | RPS19BP1 | 91582 | 3 | 6 | 61 | |
| GSE54994 | RPS19BP1 | 91582 | 10 | 7 | 36 | |
| GSE60625 | RPS19BP1 | 91582 | 5 | 0 | 6 | |
| GSE74703 | RPS19BP1 | 91582 | 5 | 4 | 27 | |
| GSE74704 | RPS19BP1 | 91582 | 3 | 2 | 15 | |
| TCGA | RPS19BP1 | 91582 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.
Somatic mutations of RPS19BP1:
Generating mutation plots.
Highly correlated genes for RPS19BP1:
Showing top 20/709 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS19BP1 | NOL9 | 0.847275 | 3 | 0 | 3 |
| RPS19BP1 | CEP290 | 0.833311 | 3 | 0 | 3 |
| RPS19BP1 | NAP1L1 | 0.822013 | 3 | 0 | 3 |
| RPS19BP1 | MAGOHB | 0.809238 | 3 | 0 | 3 |
| RPS19BP1 | TAF6 | 0.808653 | 3 | 0 | 3 |
| RPS19BP1 | TUBGCP4 | 0.805452 | 3 | 0 | 3 |
| RPS19BP1 | PRR14 | 0.798565 | 3 | 0 | 3 |
| RPS19BP1 | PEX10 | 0.792538 | 3 | 0 | 3 |
| RPS19BP1 | CHCHD2 | 0.788427 | 4 | 0 | 4 |
| RPS19BP1 | TCTN1 | 0.787149 | 3 | 0 | 3 |
| RPS19BP1 | DHX40 | 0.779073 | 3 | 0 | 3 |
| RPS19BP1 | DDX54 | 0.775541 | 4 | 0 | 4 |
| RPS19BP1 | SMG9 | 0.767139 | 3 | 0 | 3 |
| RPS19BP1 | UBE2N | 0.766665 | 3 | 0 | 3 |
| RPS19BP1 | USP42 | 0.765039 | 3 | 0 | 3 |
| RPS19BP1 | ZXDB | 0.762036 | 3 | 0 | 3 |
| RPS19BP1 | SLC7A6 | 0.761322 | 3 | 0 | 3 |
| RPS19BP1 | RPS27A | 0.758038 | 3 | 0 | 3 |
| RPS19BP1 | FMR1 | 0.756463 | 3 | 0 | 3 |
| RPS19BP1 | ACD | 0.754165 | 3 | 0 | 3 |
For details and further investigation, click here
