| Full name: heat shock protein family A (Hsp70) member 12A | Alias Symbol: FLJ13874|KIAA0417 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 259217 | HGNC ID: HGNC:19022 | Ensembl Gene: ENSG00000165868 | OMIM ID: 610701 |
| Drug and gene relationship at DGIdb | |||
Expression of HSPA12A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPA12A | 259217 | 214434_at | -0.1659 | 0.8426 | |
| GSE20347 | HSPA12A | 259217 | 214434_at | 0.4671 | 0.0131 | |
| GSE23400 | HSPA12A | 259217 | 214434_at | -0.0251 | 0.7417 | |
| GSE26886 | HSPA12A | 259217 | 214434_at | 0.8835 | 0.0001 | |
| GSE29001 | HSPA12A | 259217 | 214434_at | 0.4408 | 0.0541 | |
| GSE38129 | HSPA12A | 259217 | 214434_at | -0.1114 | 0.7452 | |
| GSE45670 | HSPA12A | 259217 | 214434_at | -0.5846 | 0.1300 | |
| GSE53622 | HSPA12A | 259217 | 74257 | -0.0372 | 0.8526 | |
| GSE53624 | HSPA12A | 259217 | 74257 | 0.2238 | 0.0773 | |
| GSE63941 | HSPA12A | 259217 | 214434_at | -1.9900 | 0.0083 | |
| GSE77861 | HSPA12A | 259217 | 220763_at | 0.0264 | 0.8127 | |
| GSE97050 | HSPA12A | 259217 | A_23_P408376 | -0.6274 | 0.2556 | |
| SRP007169 | HSPA12A | 259217 | RNAseq | 1.5320 | 0.0292 | |
| SRP008496 | HSPA12A | 259217 | RNAseq | 3.2329 | 0.0000 | |
| SRP064894 | HSPA12A | 259217 | RNAseq | 0.5573 | 0.0879 | |
| SRP133303 | HSPA12A | 259217 | RNAseq | 0.5706 | 0.0797 | |
| SRP159526 | HSPA12A | 259217 | RNAseq | 0.9528 | 0.0198 | |
| SRP193095 | HSPA12A | 259217 | RNAseq | 1.9801 | 0.0000 | |
| SRP219564 | HSPA12A | 259217 | RNAseq | 0.2910 | 0.6534 | |
| TCGA | HSPA12A | 259217 | RNAseq | 0.0047 | 0.9735 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by HSPA12A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPA12A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPA12A | 259217 | 1 | 7 | 22 | |
| GSE20123 | HSPA12A | 259217 | 1 | 7 | 22 | |
| GSE43470 | HSPA12A | 259217 | 0 | 9 | 34 | |
| GSE46452 | HSPA12A | 259217 | 0 | 11 | 48 | |
| GSE47630 | HSPA12A | 259217 | 2 | 14 | 24 | |
| GSE54993 | HSPA12A | 259217 | 8 | 0 | 62 | |
| GSE54994 | HSPA12A | 259217 | 1 | 9 | 43 | |
| GSE60625 | HSPA12A | 259217 | 0 | 0 | 11 | |
| GSE74703 | HSPA12A | 259217 | 0 | 6 | 30 | |
| GSE74704 | HSPA12A | 259217 | 1 | 3 | 16 | |
| TCGA | HSPA12A | 259217 | 4 | 29 | 63 |
Total number of gains: 18; Total number of losses: 95; Total Number of normals: 375.
Somatic mutations of HSPA12A:
Generating mutation plots.
Highly correlated genes for HSPA12A:
Showing top 20/960 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPA12A | ANO5 | 0.814951 | 3 | 0 | 3 |
| HSPA12A | DNAJC18 | 0.763526 | 3 | 0 | 3 |
| HSPA12A | MAPRE3 | 0.756779 | 3 | 0 | 3 |
| HSPA12A | RGS7BP | 0.756519 | 3 | 0 | 3 |
| HSPA12A | HAGH | 0.756289 | 3 | 0 | 3 |
| HSPA12A | CDKL3 | 0.748857 | 3 | 0 | 3 |
| HSPA12A | CKMT2 | 0.747399 | 4 | 0 | 4 |
| HSPA12A | FAM98B | 0.738306 | 3 | 0 | 3 |
| HSPA12A | ESRRG | 0.736103 | 3 | 0 | 3 |
| HSPA12A | TRIM47 | 0.731809 | 3 | 0 | 3 |
| HSPA12A | BEND5 | 0.724865 | 3 | 0 | 3 |
| HSPA12A | FGL2 | 0.712947 | 5 | 0 | 5 |
| HSPA12A | SNCA | 0.708311 | 3 | 0 | 3 |
| HSPA12A | EPHA7 | 0.704976 | 4 | 0 | 4 |
| HSPA12A | PACS1 | 0.703395 | 3 | 0 | 3 |
| HSPA12A | MGARP | 0.701648 | 3 | 0 | 3 |
| HSPA12A | PI16 | 0.69644 | 4 | 0 | 4 |
| HSPA12A | TIMP3 | 0.695386 | 8 | 0 | 8 |
| HSPA12A | CDC42EP4 | 0.691932 | 3 | 0 | 3 |
| HSPA12A | MAN1C1 | 0.691291 | 4 | 0 | 3 |
For details and further investigation, click here
