| Full name: exostosin like glycosyltransferase 1 | Alias Symbol: EXTL|MGC70794 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 2134 | HGNC ID: HGNC:3515 | Ensembl Gene: ENSG00000158008 | OMIM ID: 601738 |
| Drug and gene relationship at DGIdb | |||
Expression of EXTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXTL1 | 2134 | 206329_at | 0.1676 | 0.4038 | |
| GSE20347 | EXTL1 | 2134 | 206329_at | -0.0192 | 0.8125 | |
| GSE23400 | EXTL1 | 2134 | 206329_at | -0.0545 | 0.1014 | |
| GSE26886 | EXTL1 | 2134 | 206329_at | 0.4257 | 0.0054 | |
| GSE29001 | EXTL1 | 2134 | 206329_at | -0.1423 | 0.2111 | |
| GSE38129 | EXTL1 | 2134 | 206329_at | -0.1194 | 0.1407 | |
| GSE45670 | EXTL1 | 2134 | 206329_at | -0.0950 | 0.4268 | |
| GSE53622 | EXTL1 | 2134 | 47830 | 0.2040 | 0.0120 | |
| GSE53624 | EXTL1 | 2134 | 47830 | 0.2009 | 0.0023 | |
| GSE63941 | EXTL1 | 2134 | 206329_at | 0.1298 | 0.5023 | |
| GSE77861 | EXTL1 | 2134 | 206329_at | -0.0375 | 0.7914 | |
| TCGA | EXTL1 | 2134 | RNAseq | -0.6881 | 0.1131 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EXTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXTL1 | 2134 | 0 | 6 | 24 | |
| GSE20123 | EXTL1 | 2134 | 0 | 5 | 25 | |
| GSE43470 | EXTL1 | 2134 | 2 | 6 | 35 | |
| GSE46452 | EXTL1 | 2134 | 5 | 1 | 53 | |
| GSE47630 | EXTL1 | 2134 | 8 | 3 | 29 | |
| GSE54993 | EXTL1 | 2134 | 2 | 1 | 67 | |
| GSE54994 | EXTL1 | 2134 | 10 | 4 | 39 | |
| GSE60625 | EXTL1 | 2134 | 0 | 0 | 11 | |
| GSE74703 | EXTL1 | 2134 | 1 | 4 | 31 | |
| GSE74704 | EXTL1 | 2134 | 0 | 0 | 20 | |
| TCGA | EXTL1 | 2134 | 9 | 24 | 63 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of EXTL1:
Generating mutation plots.
Highly correlated genes for EXTL1:
Showing top 20/717 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXTL1 | NFAM1 | 0.781529 | 3 | 0 | 3 |
| EXTL1 | STAC3 | 0.758322 | 3 | 0 | 3 |
| EXTL1 | LINC00475 | 0.756842 | 4 | 0 | 4 |
| EXTL1 | CCL7 | 0.735106 | 3 | 0 | 3 |
| EXTL1 | VCX2 | 0.73192 | 4 | 0 | 4 |
| EXTL1 | CTDSP1 | 0.724751 | 3 | 0 | 3 |
| EXTL1 | ADAMTS10 | 0.715244 | 3 | 0 | 3 |
| EXTL1 | SGCA | 0.707544 | 4 | 0 | 4 |
| EXTL1 | TMEM102 | 0.699962 | 3 | 0 | 3 |
| EXTL1 | ELAVL3 | 0.698172 | 5 | 0 | 5 |
| EXTL1 | HDAC7 | 0.696856 | 4 | 0 | 3 |
| EXTL1 | SCUBE1 | 0.692575 | 4 | 0 | 3 |
| EXTL1 | ZNF358 | 0.684376 | 3 | 0 | 3 |
| EXTL1 | FFAR1 | 0.677476 | 3 | 0 | 3 |
| EXTL1 | ATXN2L | 0.675676 | 6 | 0 | 6 |
| EXTL1 | MAPK15 | 0.675625 | 4 | 0 | 4 |
| EXTL1 | LINC00313 | 0.670851 | 3 | 0 | 3 |
| EXTL1 | RIMS4 | 0.66875 | 5 | 0 | 4 |
| EXTL1 | RBBP8NL | 0.66396 | 3 | 0 | 3 |
| EXTL1 | SIRT6 | 0.663734 | 4 | 0 | 4 |
For details and further investigation, click here
