| Full name: synaptopodin | Alias Symbol: KIAA1029 | ||
| Type: protein-coding gene | Cytoband: 5q33.1 | ||
| Entrez ID: 11346 | HGNC ID: HGNC:30672 | Ensembl Gene: ENSG00000171992 | OMIM ID: 608155 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNPO | 11346 | 202796_at | 0.5034 | 0.3321 | |
| GSE20347 | SYNPO | 11346 | 202796_at | 0.3736 | 0.0465 | |
| GSE23400 | SYNPO | 11346 | 202796_at | -0.0752 | 0.4182 | |
| GSE26886 | SYNPO | 11346 | 202796_at | 1.2196 | 0.0015 | |
| GSE29001 | SYNPO | 11346 | 202796_at | 0.6006 | 0.1837 | |
| GSE38129 | SYNPO | 11346 | 202796_at | -0.0449 | 0.8991 | |
| GSE45670 | SYNPO | 11346 | 202796_at | -0.1117 | 0.7848 | |
| GSE53622 | SYNPO | 11346 | 117769 | -0.3312 | 0.0014 | |
| GSE53624 | SYNPO | 11346 | 117769 | -0.9644 | 0.0000 | |
| GSE63941 | SYNPO | 11346 | 202796_at | -1.8484 | 0.0623 | |
| GSE77861 | SYNPO | 11346 | 235128_at | -0.0277 | 0.8217 | |
| GSE97050 | SYNPO | 11346 | A_33_P3397658 | 0.2362 | 0.2654 | |
| SRP007169 | SYNPO | 11346 | RNAseq | 1.3114 | 0.0285 | |
| SRP008496 | SYNPO | 11346 | RNAseq | 2.4486 | 0.0000 | |
| SRP064894 | SYNPO | 11346 | RNAseq | 0.5718 | 0.0082 | |
| SRP133303 | SYNPO | 11346 | RNAseq | 0.6326 | 0.0536 | |
| SRP159526 | SYNPO | 11346 | RNAseq | 0.1389 | 0.5792 | |
| SRP193095 | SYNPO | 11346 | RNAseq | 1.4212 | 0.0000 | |
| SRP219564 | SYNPO | 11346 | RNAseq | 0.4442 | 0.4880 | |
| TCGA | SYNPO | 11346 | RNAseq | -0.2392 | 0.0061 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SYNPO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYNPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNPO | 11346 | 1 | 12 | 17 | |
| GSE20123 | SYNPO | 11346 | 1 | 12 | 17 | |
| GSE43470 | SYNPO | 11346 | 1 | 10 | 32 | |
| GSE46452 | SYNPO | 11346 | 0 | 27 | 32 | |
| GSE47630 | SYNPO | 11346 | 0 | 20 | 20 | |
| GSE54993 | SYNPO | 11346 | 9 | 1 | 60 | |
| GSE54994 | SYNPO | 11346 | 2 | 15 | 36 | |
| GSE60625 | SYNPO | 11346 | 0 | 0 | 11 | |
| GSE74703 | SYNPO | 11346 | 1 | 7 | 28 | |
| GSE74704 | SYNPO | 11346 | 1 | 7 | 12 | |
| TCGA | SYNPO | 11346 | 5 | 37 | 54 |
Total number of gains: 21; Total number of losses: 148; Total Number of normals: 319.
Somatic mutations of SYNPO:
Generating mutation plots.
Highly correlated genes for SYNPO:
Showing top 20/317 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNPO | GXYLT2 | 0.733443 | 4 | 0 | 4 |
| SYNPO | HDAC7 | 0.696797 | 3 | 0 | 3 |
| SYNPO | ANO6 | 0.691424 | 3 | 0 | 3 |
| SYNPO | SLC45A3 | 0.686684 | 3 | 0 | 3 |
| SYNPO | TTYH2 | 0.680074 | 5 | 0 | 4 |
| SYNPO | LTBP2 | 0.675873 | 7 | 0 | 7 |
| SYNPO | NLRC4 | 0.674478 | 3 | 0 | 3 |
| SYNPO | S1PR4 | 0.673301 | 3 | 0 | 3 |
| SYNPO | DENND5B | 0.659692 | 4 | 0 | 4 |
| SYNPO | MEGF8 | 0.659087 | 3 | 0 | 3 |
| SYNPO | EDN1 | 0.65522 | 3 | 0 | 3 |
| SYNPO | RGL1 | 0.653206 | 3 | 0 | 3 |
| SYNPO | LHFPL2 | 0.651922 | 8 | 0 | 8 |
| SYNPO | COL17A1 | 0.642147 | 3 | 0 | 3 |
| SYNPO | HYI | 0.641627 | 4 | 0 | 3 |
| SYNPO | C1orf216 | 0.634665 | 7 | 0 | 7 |
| SYNPO | SORCS2 | 0.633741 | 3 | 0 | 3 |
| SYNPO | ATP8B4 | 0.632734 | 3 | 0 | 3 |
| SYNPO | OXTR | 0.632651 | 3 | 0 | 3 |
| SYNPO | GPX8 | 0.631747 | 4 | 0 | 4 |
For details and further investigation, click here
