| Full name: FMR1 autosomal homolog 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 9513 | HGNC ID: HGNC:4024 | Ensembl Gene: ENSG00000129245 | OMIM ID: 605339 |
| Drug and gene relationship at DGIdb | |||
Expression of FXR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FXR2 | 9513 | 35265_at | 0.3262 | 0.2888 | |
| GSE20347 | FXR2 | 9513 | 35265_at | 0.1563 | 0.1451 | |
| GSE23400 | FXR2 | 9513 | 35265_at | 0.0322 | 0.5580 | |
| GSE26886 | FXR2 | 9513 | 35265_at | 0.4860 | 0.0002 | |
| GSE29001 | FXR2 | 9513 | 35265_at | -0.1983 | 0.3886 | |
| GSE38129 | FXR2 | 9513 | 35265_at | 0.1588 | 0.0658 | |
| GSE45670 | FXR2 | 9513 | 203172_at | 0.2207 | 0.0087 | |
| GSE53622 | FXR2 | 9513 | 126080 | 0.2626 | 0.0000 | |
| GSE53624 | FXR2 | 9513 | 126080 | 0.4296 | 0.0000 | |
| GSE63941 | FXR2 | 9513 | 35265_at | -0.0914 | 0.7608 | |
| GSE77861 | FXR2 | 9513 | 35265_at | 0.2098 | 0.3439 | |
| GSE97050 | FXR2 | 9513 | A_23_P4007 | 0.0013 | 0.9962 | |
| SRP007169 | FXR2 | 9513 | RNAseq | 0.3076 | 0.4405 | |
| SRP008496 | FXR2 | 9513 | RNAseq | 0.4041 | 0.0832 | |
| SRP064894 | FXR2 | 9513 | RNAseq | 0.1881 | 0.1443 | |
| SRP133303 | FXR2 | 9513 | RNAseq | 0.1039 | 0.4844 | |
| SRP159526 | FXR2 | 9513 | RNAseq | 0.4833 | 0.0159 | |
| SRP193095 | FXR2 | 9513 | RNAseq | 0.4595 | 0.0000 | |
| SRP219564 | FXR2 | 9513 | RNAseq | 0.1218 | 0.6866 | |
| TCGA | FXR2 | 9513 | RNAseq | -0.0293 | 0.5576 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FXR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FXR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FXR2 | 9513 | 4 | 2 | 24 | |
| GSE20123 | FXR2 | 9513 | 4 | 3 | 23 | |
| GSE43470 | FXR2 | 9513 | 1 | 6 | 36 | |
| GSE46452 | FXR2 | 9513 | 34 | 1 | 24 | |
| GSE47630 | FXR2 | 9513 | 7 | 1 | 32 | |
| GSE54993 | FXR2 | 9513 | 4 | 3 | 63 | |
| GSE54994 | FXR2 | 9513 | 5 | 8 | 40 | |
| GSE60625 | FXR2 | 9513 | 4 | 0 | 7 | |
| GSE74703 | FXR2 | 9513 | 1 | 3 | 32 | |
| GSE74704 | FXR2 | 9513 | 2 | 1 | 17 | |
| TCGA | FXR2 | 9513 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of FXR2:
Generating mutation plots.
Highly correlated genes for FXR2:
Showing top 20/679 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FXR2 | GOSR1 | 0.774122 | 4 | 0 | 4 |
| FXR2 | RILP | 0.770888 | 3 | 0 | 3 |
| FXR2 | LRP5L | 0.759879 | 3 | 0 | 3 |
| FXR2 | HMBOX1 | 0.746104 | 3 | 0 | 3 |
| FXR2 | CD180 | 0.743908 | 3 | 0 | 3 |
| FXR2 | PARN | 0.727074 | 3 | 0 | 3 |
| FXR2 | SLC39A3 | 0.713794 | 5 | 0 | 4 |
| FXR2 | CREB5 | 0.71052 | 3 | 0 | 3 |
| FXR2 | DVL1 | 0.710362 | 3 | 0 | 3 |
| FXR2 | A1BG | 0.708404 | 3 | 0 | 3 |
| FXR2 | GATAD2B | 0.708112 | 3 | 0 | 3 |
| FXR2 | METTL16 | 0.705331 | 3 | 0 | 3 |
| FXR2 | TRMT61A | 0.704396 | 4 | 0 | 4 |
| FXR2 | GNA11 | 0.702982 | 3 | 0 | 3 |
| FXR2 | ZFYVE9 | 0.699292 | 4 | 0 | 3 |
| FXR2 | KDM6B | 0.69833 | 6 | 0 | 5 |
| FXR2 | SYDE1 | 0.696729 | 4 | 0 | 4 |
| FXR2 | LNP1 | 0.696158 | 3 | 0 | 3 |
| FXR2 | TULP4 | 0.6928 | 3 | 0 | 3 |
| FXR2 | HDAC7 | 0.691473 | 5 | 0 | 5 |
For details and further investigation, click here
