| Full name: family with sequence similarity 53 member A | Alias Symbol: DNTNP | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 152877 | HGNC ID: HGNC:31860 | Ensembl Gene: ENSG00000174137 | OMIM ID: 617229 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM53A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM53A | 152877 | 1569139_s_at | 0.5671 | 0.1865 | |
| GSE26886 | FAM53A | 152877 | 236206_at | 0.3515 | 0.0100 | |
| GSE45670 | FAM53A | 152877 | 1569139_s_at | 0.3392 | 0.0766 | |
| GSE53622 | FAM53A | 152877 | 154007 | -0.2125 | 0.0990 | |
| GSE53624 | FAM53A | 152877 | 154007 | -0.0127 | 0.8989 | |
| GSE63941 | FAM53A | 152877 | 1569139_s_at | -0.1318 | 0.8503 | |
| GSE77861 | FAM53A | 152877 | 236206_at | -0.0761 | 0.6872 | |
| SRP133303 | FAM53A | 152877 | RNAseq | 0.0644 | 0.8388 | |
| SRP159526 | FAM53A | 152877 | RNAseq | 0.8149 | 0.1686 | |
| SRP219564 | FAM53A | 152877 | RNAseq | 1.0714 | 0.1570 | |
| TCGA | FAM53A | 152877 | RNAseq | 0.0852 | 0.7295 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM53A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM53A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM53A | 152877 | 0 | 16 | 14 | |
| GSE20123 | FAM53A | 152877 | 0 | 16 | 14 | |
| GSE43470 | FAM53A | 152877 | 0 | 17 | 26 | |
| GSE46452 | FAM53A | 152877 | 1 | 36 | 22 | |
| GSE47630 | FAM53A | 152877 | 2 | 19 | 19 | |
| GSE54993 | FAM53A | 152877 | 11 | 0 | 59 | |
| GSE54994 | FAM53A | 152877 | 3 | 12 | 38 | |
| GSE60625 | FAM53A | 152877 | 0 | 0 | 11 | |
| GSE74703 | FAM53A | 152877 | 0 | 13 | 23 | |
| GSE74704 | FAM53A | 152877 | 0 | 8 | 12 | |
| TCGA | FAM53A | 152877 | 9 | 47 | 40 |
Total number of gains: 26; Total number of losses: 184; Total Number of normals: 278.
Somatic mutations of FAM53A:
Generating mutation plots.
Highly correlated genes for FAM53A:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM53A | CBS | 0.761842 | 3 | 0 | 3 |
| FAM53A | ZNF408 | 0.732516 | 3 | 0 | 3 |
| FAM53A | ZNF579 | 0.72725 | 3 | 0 | 3 |
| FAM53A | SYCE1L | 0.718227 | 3 | 0 | 3 |
| FAM53A | MEX3D | 0.710015 | 3 | 0 | 3 |
| FAM53A | LIPE | 0.709822 | 3 | 0 | 3 |
| FAM53A | MIER2 | 0.707351 | 3 | 0 | 3 |
| FAM53A | TRMT61A | 0.706768 | 3 | 0 | 3 |
| FAM53A | TFEB | 0.702592 | 3 | 0 | 3 |
| FAM53A | HDAC7 | 0.701828 | 3 | 0 | 3 |
| FAM53A | FRS3 | 0.684992 | 3 | 0 | 3 |
| FAM53A | BRPF1 | 0.673008 | 3 | 0 | 3 |
| FAM53A | ZMIZ2 | 0.670568 | 3 | 0 | 3 |
| FAM53A | SAMD1 | 0.670526 | 3 | 0 | 3 |
| FAM53A | IL4 | 0.669174 | 3 | 0 | 3 |
| FAM53A | ASB6 | 0.668362 | 3 | 0 | 3 |
| FAM53A | GAS6-AS1 | 0.657829 | 3 | 0 | 3 |
| FAM53A | MAP2K7 | 0.657062 | 3 | 0 | 3 |
| FAM53A | HOXD9 | 0.654781 | 4 | 0 | 4 |
| FAM53A | LIMD1 | 0.65429 | 3 | 0 | 3 |
For details and further investigation, click here
