PRDM13

 

Full name: PR/SET domain 13 Alias Symbol: PFM10
Type: protein-coding gene Cytoband: 6q16.2
Entrez ID: 59336 HGNC ID: HGNC:13998 Ensembl Gene: ENSG00000112238 OMIM ID: 616741
Drug and gene relationship at DGIdb

 

Expression of PRDM13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRDM13 59336 221168_at 0.8661 0.1866
GSE20347 PRDM13 59336 221168_at 0.2649 0.0578
GSE23400 PRDM13 59336 221168_at 0.1033 0.0009
GSE26886 PRDM13 59336 221168_at 0.9962 0.0009
GSE29001 PRDM13 59336 221168_at 0.7590 0.0034
GSE38129 PRDM13 59336 221168_at 0.4823 0.0017
GSE45670 PRDM13 59336 221168_at 0.6755 0.0154
GSE53622 PRDM13 59336 101879 0.2795 0.0002
GSE53624 PRDM13 59336 101879 0.4630 0.0000
GSE63941 PRDM13 59336 221168_at 1.3311 0.2198
GSE77861 PRDM13 59336 221168_at 0.0375 0.7777
GSE97050 PRDM13 59336 A_33_P3214803 0.1294 0.6414
TCGA PRDM13 59336 RNAseq 2.6024 0.0001

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by PRDM13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PRDM13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRDM13 59336 2 3 25
GSE20123 PRDM13 59336 2 2 26
GSE43470 PRDM13 59336 3 0 40
GSE46452 PRDM13 59336 2 11 46
GSE47630 PRDM13 59336 8 6 26
GSE54993 PRDM13 59336 3 2 65
GSE54994 PRDM13 59336 8 8 37
GSE60625 PRDM13 59336 0 1 10
GSE74703 PRDM13 59336 2 0 34
GSE74704 PRDM13 59336 1 0 19
TCGA PRDM13 59336 7 24 65

Total number of gains: 38; Total number of losses: 57; Total Number of normals: 393.  


 

Somatic mutations of PRDM13:

 

Generating mutation plots.

 

Highly correlated genes for PRDM13:

 

Showing top 20/385 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRDM13TMEM2350.832781303
PRDM13C2CD4D0.831467303
PRDM13C19orf710.826488303
PRDM13MRGPRG0.825262303
PRDM13STRC0.805367303
PRDM13LHB0.787295303
PRDM13C1QL20.786215303
PRDM13TCTE10.783437303
PRDM13SORCS30.783255303
PRDM13GHSR0.782915303
PRDM13C9orf1530.782315303
PRDM13DCDC10.771026303
PRDM13BLACE0.768968303
PRDM13DEFB1210.759869303
PRDM13SPACA30.754447303
PRDM13PLA2G2C0.754371303
PRDM13YY20.753867303
PRDM13POM121L120.749532404
PRDM13SLC18A30.749371303
PRDM13SLC22A110.745119303

For details and further investigation, click here