| Full name: tripartite motif containing 46 | Alias Symbol: FLJ23229|TRIFIC | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 80128 | HGNC ID: HGNC:19019 | Ensembl Gene: ENSG00000163462 | OMIM ID: 600986 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM46 | 80128 | 238147_at | 0.2484 | 0.2306 | |
| GSE20347 | TRIM46 | 80128 | 220909_at | -0.1008 | 0.1079 | |
| GSE23400 | TRIM46 | 80128 | 220909_at | -0.1101 | 0.0000 | |
| GSE26886 | TRIM46 | 80128 | 238147_at | 0.2391 | 0.0857 | |
| GSE29001 | TRIM46 | 80128 | 220909_at | -0.1305 | 0.2126 | |
| GSE38129 | TRIM46 | 80128 | 220909_at | -0.0449 | 0.5634 | |
| GSE45670 | TRIM46 | 80128 | 238147_at | 0.1007 | 0.1742 | |
| GSE53622 | TRIM46 | 80128 | 42798 | 0.4878 | 0.0000 | |
| GSE53624 | TRIM46 | 80128 | 42798 | 0.3782 | 0.0000 | |
| GSE63941 | TRIM46 | 80128 | 238147_at | -0.3391 | 0.0814 | |
| GSE77861 | TRIM46 | 80128 | 238147_at | -0.1191 | 0.3055 | |
| GSE97050 | TRIM46 | 80128 | A_23_P46222 | 0.0695 | 0.7370 | |
| SRP064894 | TRIM46 | 80128 | RNAseq | 0.5142 | 0.0966 | |
| SRP133303 | TRIM46 | 80128 | RNAseq | -0.3048 | 0.2869 | |
| SRP159526 | TRIM46 | 80128 | RNAseq | 1.3933 | 0.0046 | |
| SRP193095 | TRIM46 | 80128 | RNAseq | 0.1942 | 0.4284 | |
| SRP219564 | TRIM46 | 80128 | RNAseq | 0.3820 | 0.5293 | |
| TCGA | TRIM46 | 80128 | RNAseq | 0.1380 | 0.4915 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRIM46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM46 | 80128 | 14 | 0 | 16 | |
| GSE20123 | TRIM46 | 80128 | 13 | 0 | 17 | |
| GSE43470 | TRIM46 | 80128 | 6 | 2 | 35 | |
| GSE46452 | TRIM46 | 80128 | 2 | 1 | 56 | |
| GSE47630 | TRIM46 | 80128 | 14 | 0 | 26 | |
| GSE54993 | TRIM46 | 80128 | 0 | 4 | 66 | |
| GSE54994 | TRIM46 | 80128 | 16 | 0 | 37 | |
| GSE60625 | TRIM46 | 80128 | 0 | 0 | 11 | |
| GSE74703 | TRIM46 | 80128 | 6 | 1 | 29 | |
| GSE74704 | TRIM46 | 80128 | 6 | 0 | 14 | |
| TCGA | TRIM46 | 80128 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of TRIM46:
Generating mutation plots.
Highly correlated genes for TRIM46:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM46 | NTNG2 | 0.866141 | 3 | 0 | 3 |
| TRIM46 | YY2 | 0.850441 | 3 | 0 | 3 |
| TRIM46 | C9orf153 | 0.833462 | 3 | 0 | 3 |
| TRIM46 | NCR3 | 0.830938 | 3 | 0 | 3 |
| TRIM46 | MRGPRG | 0.822203 | 3 | 0 | 3 |
| TRIM46 | OR10AD1 | 0.819759 | 3 | 0 | 3 |
| TRIM46 | MS4A18 | 0.814842 | 3 | 0 | 3 |
| TRIM46 | STRC | 0.802709 | 3 | 0 | 3 |
| TRIM46 | DCDC1 | 0.799983 | 3 | 0 | 3 |
| TRIM46 | OR2T1 | 0.792245 | 3 | 0 | 3 |
| TRIM46 | CDKL4 | 0.791272 | 3 | 0 | 3 |
| TRIM46 | KRTAP10-12 | 0.789471 | 3 | 0 | 3 |
| TRIM46 | C1QL2 | 0.788314 | 3 | 0 | 3 |
| TRIM46 | C19orf71 | 0.787623 | 3 | 0 | 3 |
| TRIM46 | TAS2R31 | 0.783313 | 3 | 0 | 3 |
| TRIM46 | OR2T27 | 0.783266 | 3 | 0 | 3 |
| TRIM46 | PRSS38 | 0.778334 | 3 | 0 | 3 |
| TRIM46 | LBX2 | 0.771391 | 3 | 0 | 3 |
| TRIM46 | OR2A5 | 0.77036 | 3 | 0 | 3 |
| TRIM46 | PLA2G2C | 0.769967 | 3 | 0 | 3 |
For details and further investigation, click here
