| Full name: heterogeneous nuclear ribonucleoprotein A1 | Alias Symbol: hnRNPA1|hnRNP-A1|ALS20 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3178 | HGNC ID: HGNC:5031 | Ensembl Gene: ENSG00000135486 | OMIM ID: 164017 |
| Drug and gene relationship at DGIdb | |||
Expression of HNRNPA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HNRNPA1 | 3178 | 214280_x_at | 0.0277 | 0.9510 | |
| GSE20347 | HNRNPA1 | 3178 | 214280_x_at | 0.3992 | 0.0010 | |
| GSE23400 | HNRNPA1 | 3178 | 214280_x_at | 0.4936 | 0.0000 | |
| GSE26886 | HNRNPA1 | 3178 | 214280_x_at | -0.4439 | 0.1047 | |
| GSE29001 | HNRNPA1 | 3178 | 214280_x_at | 0.3437 | 0.1812 | |
| GSE38129 | HNRNPA1 | 3178 | 214280_x_at | 0.5134 | 0.0000 | |
| GSE45670 | HNRNPA1 | 3178 | 214280_x_at | 0.0341 | 0.8240 | |
| GSE53622 | HNRNPA1 | 3178 | 25015 | 0.0794 | 0.1458 | |
| GSE53624 | HNRNPA1 | 3178 | 25015 | 0.4140 | 0.0000 | |
| GSE63941 | HNRNPA1 | 3178 | 214280_x_at | 0.4349 | 0.3541 | |
| GSE77861 | HNRNPA1 | 3178 | 214280_x_at | 0.2603 | 0.3509 | |
| GSE97050 | HNRNPA1 | 3178 | A_32_P42197 | -0.0057 | 0.9808 | |
| SRP007169 | HNRNPA1 | 3178 | RNAseq | -0.0973 | 0.7693 | |
| SRP008496 | HNRNPA1 | 3178 | RNAseq | -0.1038 | 0.6037 | |
| SRP064894 | HNRNPA1 | 3178 | RNAseq | -0.0592 | 0.6932 | |
| SRP133303 | HNRNPA1 | 3178 | RNAseq | -0.0336 | 0.7574 | |
| SRP159526 | HNRNPA1 | 3178 | RNAseq | -0.0991 | 0.6564 | |
| SRP193095 | HNRNPA1 | 3178 | RNAseq | -0.3340 | 0.0298 | |
| SRP219564 | HNRNPA1 | 3178 | RNAseq | 0.2414 | 0.3706 | |
| TCGA | HNRNPA1 | 3178 | RNAseq | 0.1040 | 0.0121 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HNRNPA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPA1 | 3178 | 4 | 1 | 25 | |
| GSE20123 | HNRNPA1 | 3178 | 4 | 1 | 25 | |
| GSE43470 | HNRNPA1 | 3178 | 3 | 0 | 40 | |
| GSE46452 | HNRNPA1 | 3178 | 7 | 1 | 51 | |
| GSE47630 | HNRNPA1 | 3178 | 10 | 2 | 28 | |
| GSE54993 | HNRNPA1 | 3178 | 0 | 5 | 65 | |
| GSE54994 | HNRNPA1 | 3178 | 4 | 1 | 48 | |
| GSE60625 | HNRNPA1 | 3178 | 0 | 0 | 11 | |
| GSE74703 | HNRNPA1 | 3178 | 3 | 0 | 33 | |
| GSE74704 | HNRNPA1 | 3178 | 3 | 1 | 16 | |
| TCGA | HNRNPA1 | 3178 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of HNRNPA1:
Generating mutation plots.
Highly correlated genes for HNRNPA1:
Showing top 20/607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPA1 | DMAP1 | 0.80862 | 3 | 0 | 3 |
| HNRNPA1 | TCF7L2 | 0.798493 | 3 | 0 | 3 |
| HNRNPA1 | TOPORS | 0.778808 | 3 | 0 | 3 |
| HNRNPA1 | PHF2 | 0.772489 | 3 | 0 | 3 |
| HNRNPA1 | ZNF324 | 0.771375 | 3 | 0 | 3 |
| HNRNPA1 | GTPBP6 | 0.766123 | 4 | 0 | 4 |
| HNRNPA1 | AKAP17A | 0.765204 | 4 | 0 | 4 |
| HNRNPA1 | ZSCAN29 | 0.764103 | 3 | 0 | 3 |
| HNRNPA1 | GGA3 | 0.757614 | 3 | 0 | 3 |
| HNRNPA1 | CEBPG | 0.752131 | 3 | 0 | 3 |
| HNRNPA1 | C5orf51 | 0.75146 | 4 | 0 | 4 |
| HNRNPA1 | ZNF830 | 0.749464 | 3 | 0 | 3 |
| HNRNPA1 | DOCK5 | 0.744884 | 3 | 0 | 3 |
| HNRNPA1 | EIF3C | 0.741291 | 3 | 0 | 3 |
| HNRNPA1 | BCL7B | 0.740895 | 3 | 0 | 3 |
| HNRNPA1 | BLCAP | 0.737541 | 4 | 0 | 4 |
| HNRNPA1 | RBMX | 0.737291 | 3 | 0 | 3 |
| HNRNPA1 | OTUD7B | 0.733991 | 3 | 0 | 3 |
| HNRNPA1 | ARID2 | 0.733148 | 3 | 0 | 3 |
| HNRNPA1 | PDXDC1 | 0.732996 | 3 | 0 | 3 |
For details and further investigation, click here
