| Full name: OTU deubiquitinase 7B | Alias Symbol: CEZANNE | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 56957 | HGNC ID: HGNC:16683 | Ensembl Gene: ENSG00000264522 | OMIM ID: 611748 |
| Drug and gene relationship at DGIdb | |||
Expression of OTUD7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTUD7B | 56957 | 227436_at | -0.0038 | 0.9954 | |
| GSE20347 | OTUD7B | 56957 | 220031_at | -0.0132 | 0.8263 | |
| GSE23400 | OTUD7B | 56957 | 220031_at | -0.0800 | 0.0065 | |
| GSE26886 | OTUD7B | 56957 | 227436_at | 0.5655 | 0.0218 | |
| GSE29001 | OTUD7B | 56957 | 220031_at | -0.1392 | 0.2552 | |
| GSE38129 | OTUD7B | 56957 | 220031_at | -0.1252 | 0.0071 | |
| GSE45670 | OTUD7B | 56957 | 227436_at | -0.2834 | 0.0134 | |
| GSE53622 | OTUD7B | 56957 | 70676 | -0.1105 | 0.2746 | |
| GSE53624 | OTUD7B | 56957 | 70676 | 0.1336 | 0.0469 | |
| GSE63941 | OTUD7B | 56957 | 227436_at | -0.2098 | 0.5207 | |
| GSE77861 | OTUD7B | 56957 | 227436_at | 0.1529 | 0.4248 | |
| GSE97050 | OTUD7B | 56957 | A_33_P3358307 | -0.2585 | 0.3380 | |
| SRP007169 | OTUD7B | 56957 | RNAseq | 0.2740 | 0.4746 | |
| SRP008496 | OTUD7B | 56957 | RNAseq | 0.2803 | 0.3149 | |
| SRP064894 | OTUD7B | 56957 | RNAseq | -0.3455 | 0.0205 | |
| SRP133303 | OTUD7B | 56957 | RNAseq | 0.2431 | 0.1216 | |
| SRP159526 | OTUD7B | 56957 | RNAseq | 0.3194 | 0.0718 | |
| SRP193095 | OTUD7B | 56957 | RNAseq | -0.0450 | 0.6591 | |
| SRP219564 | OTUD7B | 56957 | RNAseq | -0.0964 | 0.7628 | |
| TCGA | OTUD7B | 56957 | RNAseq | -0.1015 | 0.0422 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTUD7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTUD7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTUD7B | 56957 | 15 | 0 | 15 | |
| GSE20123 | OTUD7B | 56957 | 15 | 0 | 15 | |
| GSE43470 | OTUD7B | 56957 | 6 | 1 | 36 | |
| GSE46452 | OTUD7B | 56957 | 2 | 1 | 56 | |
| GSE47630 | OTUD7B | 56957 | 14 | 0 | 26 | |
| GSE54993 | OTUD7B | 56957 | 0 | 3 | 67 | |
| GSE54994 | OTUD7B | 56957 | 15 | 0 | 38 | |
| GSE60625 | OTUD7B | 56957 | 0 | 0 | 11 | |
| GSE74703 | OTUD7B | 56957 | 6 | 1 | 29 | |
| GSE74704 | OTUD7B | 56957 | 7 | 0 | 13 | |
| TCGA | OTUD7B | 56957 | 37 | 4 | 55 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of OTUD7B:
Generating mutation plots.
Highly correlated genes for OTUD7B:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTUD7B | NAA30 | 0.815782 | 3 | 0 | 3 |
| OTUD7B | CCIN | 0.794294 | 3 | 0 | 3 |
| OTUD7B | ZNF764 | 0.784793 | 3 | 0 | 3 |
| OTUD7B | LUC7L2 | 0.783919 | 3 | 0 | 3 |
| OTUD7B | ZNF578 | 0.775255 | 3 | 0 | 3 |
| OTUD7B | BOD1 | 0.772703 | 4 | 0 | 4 |
| OTUD7B | PHF13 | 0.771862 | 3 | 0 | 3 |
| OTUD7B | IPO8 | 0.771517 | 3 | 0 | 3 |
| OTUD7B | PPM1A | 0.767755 | 3 | 0 | 3 |
| OTUD7B | CAP1 | 0.76038 | 3 | 0 | 3 |
| OTUD7B | FAM122B | 0.756695 | 3 | 0 | 3 |
| OTUD7B | USP34 | 0.747167 | 3 | 0 | 3 |
| OTUD7B | RBM4 | 0.745402 | 3 | 0 | 3 |
| OTUD7B | ESCO1 | 0.743864 | 3 | 0 | 3 |
| OTUD7B | ACP6 | 0.7429 | 3 | 0 | 3 |
| OTUD7B | CSRNP2 | 0.737265 | 3 | 0 | 3 |
| OTUD7B | SHPRH | 0.737262 | 3 | 0 | 3 |
| OTUD7B | ZFP90 | 0.737211 | 3 | 0 | 3 |
| OTUD7B | CLASP1 | 0.736236 | 3 | 0 | 3 |
| OTUD7B | HNRNPA1 | 0.733991 | 3 | 0 | 3 |
For details and further investigation, click here
