| Full name: PHD finger protein 2 | Alias Symbol: KIAA0662|JHDM1E|CENP-35|KDM7C | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 5253 | HGNC ID: HGNC:8920 | Ensembl Gene: ENSG00000197724 | OMIM ID: 604351 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF2 | 5253 | 212726_at | 0.1278 | 0.8109 | |
| GSE20347 | PHF2 | 5253 | 212726_at | -0.0175 | 0.8793 | |
| GSE23400 | PHF2 | 5253 | 212726_at | 0.1869 | 0.0108 | |
| GSE26886 | PHF2 | 5253 | 212726_at | -0.5131 | 0.0079 | |
| GSE29001 | PHF2 | 5253 | 212726_at | 0.2663 | 0.2225 | |
| GSE38129 | PHF2 | 5253 | 212726_at | -0.0715 | 0.5528 | |
| GSE45670 | PHF2 | 5253 | 212726_at | -0.1679 | 0.1848 | |
| GSE53622 | PHF2 | 5253 | 106130 | -0.2917 | 0.0000 | |
| GSE53624 | PHF2 | 5253 | 106130 | -0.0366 | 0.5294 | |
| GSE63941 | PHF2 | 5253 | 212726_at | 0.4052 | 0.3092 | |
| GSE77861 | PHF2 | 5253 | 212726_at | 0.2633 | 0.1348 | |
| GSE97050 | PHF2 | 5253 | A_23_P502371 | -0.4427 | 0.1382 | |
| SRP007169 | PHF2 | 5253 | RNAseq | 0.5574 | 0.0945 | |
| SRP008496 | PHF2 | 5253 | RNAseq | 0.5149 | 0.0059 | |
| SRP064894 | PHF2 | 5253 | RNAseq | 0.0664 | 0.7134 | |
| SRP133303 | PHF2 | 5253 | RNAseq | -0.0778 | 0.4084 | |
| SRP159526 | PHF2 | 5253 | RNAseq | 0.1805 | 0.4823 | |
| SRP193095 | PHF2 | 5253 | RNAseq | 0.2826 | 0.0117 | |
| SRP219564 | PHF2 | 5253 | RNAseq | -0.0736 | 0.8312 | |
| TCGA | PHF2 | 5253 | RNAseq | -0.0634 | 0.1832 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF2 | 5253 | 5 | 9 | 16 | |
| GSE20123 | PHF2 | 5253 | 5 | 9 | 16 | |
| GSE43470 | PHF2 | 5253 | 6 | 3 | 34 | |
| GSE46452 | PHF2 | 5253 | 6 | 14 | 39 | |
| GSE47630 | PHF2 | 5253 | 1 | 17 | 22 | |
| GSE54993 | PHF2 | 5253 | 4 | 2 | 64 | |
| GSE54994 | PHF2 | 5253 | 8 | 11 | 34 | |
| GSE60625 | PHF2 | 5253 | 0 | 0 | 11 | |
| GSE74703 | PHF2 | 5253 | 5 | 3 | 28 | |
| GSE74704 | PHF2 | 5253 | 2 | 7 | 11 | |
| TCGA | PHF2 | 5253 | 24 | 24 | 48 |
Total number of gains: 66; Total number of losses: 99; Total Number of normals: 323.
Somatic mutations of PHF2:
Generating mutation plots.
Highly correlated genes for PHF2:
Showing top 20/366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF2 | C5orf51 | 0.809009 | 3 | 0 | 3 |
| PHF2 | TEX261 | 0.785495 | 3 | 0 | 3 |
| PHF2 | PURA | 0.774894 | 3 | 0 | 3 |
| PHF2 | HNRNPA1 | 0.772489 | 3 | 0 | 3 |
| PHF2 | MUS81 | 0.759193 | 3 | 0 | 3 |
| PHF2 | CDK5RAP3 | 0.751503 | 3 | 0 | 3 |
| PHF2 | PLXNB3 | 0.737048 | 3 | 0 | 3 |
| PHF2 | WDR77 | 0.734698 | 3 | 0 | 3 |
| PHF2 | DCAF16 | 0.730286 | 4 | 0 | 4 |
| PHF2 | SLC26A11 | 0.729614 | 3 | 0 | 3 |
| PHF2 | ZSCAN29 | 0.72607 | 3 | 0 | 3 |
| PHF2 | ARL6 | 0.724958 | 3 | 0 | 3 |
| PHF2 | FAM172A | 0.723681 | 3 | 0 | 3 |
| PHF2 | SESTD1 | 0.723005 | 4 | 0 | 4 |
| PHF2 | ZFYVE9 | 0.718976 | 3 | 0 | 3 |
| PHF2 | ASH2L | 0.71259 | 3 | 0 | 3 |
| PHF2 | RHBDD1 | 0.711418 | 3 | 0 | 3 |
| PHF2 | THAP5 | 0.710025 | 3 | 0 | 3 |
| PHF2 | C1orf35 | 0.703868 | 3 | 0 | 3 |
| PHF2 | R3HDM2 | 0.702773 | 5 | 0 | 4 |
For details and further investigation, click here
