| Full name: golgi associated, gamma adaptin ear containing, ARF binding protein 3 | Alias Symbol: KIAA0154 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 23163 | HGNC ID: HGNC:17079 | Ensembl Gene: ENSG00000125447 | OMIM ID: 606006 |
| Drug and gene relationship at DGIdb | |||
Expression of GGA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGA3 | 23163 | 209411_s_at | 0.1165 | 0.8289 | |
| GSE20347 | GGA3 | 23163 | 209411_s_at | -0.0804 | 0.4415 | |
| GSE23400 | GGA3 | 23163 | 209411_s_at | -0.0941 | 0.0440 | |
| GSE26886 | GGA3 | 23163 | 209411_s_at | -0.8999 | 0.0000 | |
| GSE29001 | GGA3 | 23163 | 209411_s_at | -0.0166 | 0.9672 | |
| GSE38129 | GGA3 | 23163 | 209411_s_at | -0.0924 | 0.2929 | |
| GSE45670 | GGA3 | 23163 | 209411_s_at | 0.0642 | 0.6602 | |
| GSE53622 | GGA3 | 23163 | 53136 | -0.7234 | 0.0000 | |
| GSE53624 | GGA3 | 23163 | 53136 | -0.4168 | 0.0000 | |
| GSE63941 | GGA3 | 23163 | 209411_s_at | -0.0229 | 0.9320 | |
| GSE77861 | GGA3 | 23163 | 209411_s_at | 0.2367 | 0.3015 | |
| GSE97050 | GGA3 | 23163 | A_23_P38181 | -0.2554 | 0.2616 | |
| SRP007169 | GGA3 | 23163 | RNAseq | -0.3477 | 0.3647 | |
| SRP008496 | GGA3 | 23163 | RNAseq | -0.6866 | 0.0356 | |
| SRP064894 | GGA3 | 23163 | RNAseq | -0.0611 | 0.6811 | |
| SRP133303 | GGA3 | 23163 | RNAseq | 0.0576 | 0.8032 | |
| SRP159526 | GGA3 | 23163 | RNAseq | -0.1341 | 0.4924 | |
| SRP193095 | GGA3 | 23163 | RNAseq | 0.0214 | 0.8586 | |
| SRP219564 | GGA3 | 23163 | RNAseq | 0.3945 | 0.4990 | |
| TCGA | GGA3 | 23163 | RNAseq | -0.0203 | 0.6772 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GGA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GGA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGA3 | 23163 | 6 | 2 | 22 | |
| GSE20123 | GGA3 | 23163 | 6 | 2 | 22 | |
| GSE43470 | GGA3 | 23163 | 5 | 3 | 35 | |
| GSE46452 | GGA3 | 23163 | 33 | 0 | 26 | |
| GSE47630 | GGA3 | 23163 | 8 | 1 | 31 | |
| GSE54993 | GGA3 | 23163 | 2 | 5 | 63 | |
| GSE54994 | GGA3 | 23163 | 10 | 4 | 39 | |
| GSE60625 | GGA3 | 23163 | 6 | 0 | 5 | |
| GSE74703 | GGA3 | 23163 | 5 | 1 | 30 | |
| GSE74704 | GGA3 | 23163 | 4 | 1 | 15 | |
| TCGA | GGA3 | 23163 | 32 | 10 | 54 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of GGA3:
Generating mutation plots.
Highly correlated genes for GGA3:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGA3 | CPEB4 | 0.860654 | 3 | 0 | 3 |
| GGA3 | C5orf51 | 0.839496 | 3 | 0 | 3 |
| GGA3 | PITHD1 | 0.821659 | 3 | 0 | 3 |
| GGA3 | FBXO8 | 0.813037 | 3 | 0 | 3 |
| GGA3 | VPS4B | 0.812247 | 3 | 0 | 3 |
| GGA3 | KCNAB1 | 0.80767 | 3 | 0 | 3 |
| GGA3 | IMPA1 | 0.807446 | 3 | 0 | 3 |
| GGA3 | USO1 | 0.806494 | 3 | 0 | 3 |
| GGA3 | ANKRD13A | 0.804054 | 3 | 0 | 3 |
| GGA3 | RAB11A | 0.797953 | 3 | 0 | 3 |
| GGA3 | PNKP | 0.79741 | 3 | 0 | 3 |
| GGA3 | CCNG2 | 0.792226 | 3 | 0 | 3 |
| GGA3 | SELENBP1 | 0.791722 | 3 | 0 | 3 |
| GGA3 | CLIP1 | 0.790397 | 3 | 0 | 3 |
| GGA3 | RRAGD | 0.787347 | 3 | 0 | 3 |
| GGA3 | TNKS2 | 0.787315 | 3 | 0 | 3 |
| GGA3 | DCP1A | 0.784566 | 3 | 0 | 3 |
| GGA3 | CHIC2 | 0.778238 | 3 | 0 | 3 |
| GGA3 | ZNF830 | 0.777606 | 3 | 0 | 3 |
| GGA3 | CYTH2 | 0.776112 | 3 | 0 | 3 |
For details and further investigation, click here
