DMAP1

 

Full name: DNA methyltransferase 1 associated protein 1 Alias Symbol: DNMAP1|FLJ11543|KIAA1425|DNMTAP1|EAF2|MEAF2|SWC4
Type: protein-coding gene Cytoband: 1p34.1
Entrez ID: 55929 HGNC ID: HGNC:18291 Ensembl Gene: ENSG00000178028 OMIM ID: 605077
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of DMAP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DMAP1 55929 224163_s_at 0.0971 0.8620
GSE26886 DMAP1 55929 224163_s_at 0.5920 0.0140
GSE45670 DMAP1 55929 224163_s_at 0.0146 0.9253
GSE53622 DMAP1 55929 59589 0.1840 0.0001
GSE53624 DMAP1 55929 59589 0.1523 0.0107
GSE63941 DMAP1 55929 224163_s_at -0.1782 0.7442
GSE77861 DMAP1 55929 224163_s_at 0.0510 0.8474
GSE97050 DMAP1 55929 A_23_P388780 0.0041 0.9872
SRP007169 DMAP1 55929 RNAseq 0.2616 0.5570
SRP008496 DMAP1 55929 RNAseq 0.3905 0.2374
SRP064894 DMAP1 55929 RNAseq 0.7934 0.0038
SRP133303 DMAP1 55929 RNAseq -0.1732 0.2694
SRP159526 DMAP1 55929 RNAseq 0.3493 0.3482
SRP193095 DMAP1 55929 RNAseq 0.3619 0.0415
SRP219564 DMAP1 55929 RNAseq 0.4312 0.1565
TCGA DMAP1 55929 RNAseq -0.0856 0.1167

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DMAP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DMAP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DMAP1 55929 4 3 23
GSE20123 DMAP1 55929 4 2 24
GSE43470 DMAP1 55929 7 2 34
GSE46452 DMAP1 55929 2 1 56
GSE47630 DMAP1 55929 9 3 28
GSE54993 DMAP1 55929 0 1 69
GSE54994 DMAP1 55929 13 2 38
GSE60625 DMAP1 55929 0 0 11
GSE74703 DMAP1 55929 6 1 29
GSE74704 DMAP1 55929 2 0 18
TCGA DMAP1 55929 14 16 66

Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.  

 

Somatic mutations of DMAP1:

 

Generating mutation plots.

 

Highly correlated genes for DMAP1:

 

Showing top 20/395 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DMAP1ARFGAP20.840286303
DMAP1HNRNPA10.80862303
DMAP1NOC3L0.802573303
DMAP1GPATCH10.801303
DMAP1NAA300.79637303
DMAP1EIF2D0.789949303
DMAP1UPF10.788769303
DMAP1ZNF7910.787325303
DMAP1UBE2O0.776989303
DMAP1KLC10.774289303
DMAP1PNMA10.773463303
DMAP1PACRGL0.772855303
DMAP1ZNF5500.768632303
DMAP1ZNF6720.768398303
DMAP1TSEN340.76531303
DMAP1ESCO10.765122303
DMAP1ZNF2230.763858303
DMAP1CTXN10.757385303
DMAP1GYS10.757317303
DMAP1GCDH0.754644303

For details and further investigation, click here