| Full name: BAF chromatin remodeling complex subunit BCL7B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 9275 | HGNC ID: HGNC:1005 | Ensembl Gene: ENSG00000106635 | OMIM ID: 605846 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL7B | 9275 | 202518_at | 0.3831 | 0.4922 | |
| GSE20347 | BCL7B | 9275 | 202518_at | 0.3538 | 0.0387 | |
| GSE23400 | BCL7B | 9275 | 202518_at | 0.1454 | 0.0368 | |
| GSE26886 | BCL7B | 9275 | 202518_at | -0.1221 | 0.5989 | |
| GSE29001 | BCL7B | 9275 | 202518_at | 0.1988 | 0.4149 | |
| GSE38129 | BCL7B | 9275 | 202518_at | 0.1034 | 0.5038 | |
| GSE45670 | BCL7B | 9275 | 202518_at | 0.0853 | 0.4447 | |
| GSE53622 | BCL7B | 9275 | 83941 | -0.1035 | 0.3035 | |
| GSE53624 | BCL7B | 9275 | 83941 | 0.2210 | 0.1393 | |
| GSE63941 | BCL7B | 9275 | 202518_at | 1.0095 | 0.0082 | |
| GSE77861 | BCL7B | 9275 | 202518_at | 0.1608 | 0.2641 | |
| GSE97050 | BCL7B | 9275 | A_23_P500364 | -0.3040 | 0.3896 | |
| SRP007169 | BCL7B | 9275 | RNAseq | -0.2143 | 0.5402 | |
| SRP008496 | BCL7B | 9275 | RNAseq | -0.0102 | 0.9687 | |
| SRP064894 | BCL7B | 9275 | RNAseq | 0.3329 | 0.1159 | |
| SRP133303 | BCL7B | 9275 | RNAseq | 0.2983 | 0.1083 | |
| SRP159526 | BCL7B | 9275 | RNAseq | -0.1331 | 0.5227 | |
| SRP193095 | BCL7B | 9275 | RNAseq | 0.2231 | 0.0776 | |
| SRP219564 | BCL7B | 9275 | RNAseq | -0.4377 | 0.3749 | |
| TCGA | BCL7B | 9275 | RNAseq | -0.0363 | 0.4615 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BCL7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL7B | 9275 | 14 | 1 | 15 | |
| GSE20123 | BCL7B | 9275 | 14 | 1 | 15 | |
| GSE43470 | BCL7B | 9275 | 3 | 2 | 38 | |
| GSE46452 | BCL7B | 9275 | 12 | 0 | 47 | |
| GSE47630 | BCL7B | 9275 | 7 | 2 | 31 | |
| GSE54993 | BCL7B | 9275 | 2 | 7 | 61 | |
| GSE54994 | BCL7B | 9275 | 14 | 3 | 36 | |
| GSE60625 | BCL7B | 9275 | 0 | 0 | 11 | |
| GSE74703 | BCL7B | 9275 | 3 | 1 | 32 | |
| GSE74704 | BCL7B | 9275 | 8 | 1 | 11 | |
| TCGA | BCL7B | 9275 | 45 | 7 | 44 |
Total number of gains: 122; Total number of losses: 25; Total Number of normals: 341.
Somatic mutations of BCL7B:
Generating mutation plots.
Highly correlated genes for BCL7B:
Showing top 20/543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL7B | CHD3 | 0.787722 | 3 | 0 | 3 |
| BCL7B | RIMKLA | 0.7628 | 3 | 0 | 3 |
| BCL7B | ZNF567 | 0.761306 | 3 | 0 | 3 |
| BCL7B | LBR | 0.757816 | 3 | 0 | 3 |
| BCL7B | ZNF496 | 0.752696 | 3 | 0 | 3 |
| BCL7B | DNAJC19 | 0.751407 | 3 | 0 | 3 |
| BCL7B | C3orf33 | 0.74583 | 3 | 0 | 3 |
| BCL7B | DNM1L | 0.743207 | 3 | 0 | 3 |
| BCL7B | TRA2B | 0.742743 | 4 | 0 | 3 |
| BCL7B | HNRNPA1 | 0.740895 | 3 | 0 | 3 |
| BCL7B | USP40 | 0.73402 | 3 | 0 | 3 |
| BCL7B | POLR2A | 0.729282 | 3 | 0 | 3 |
| BCL7B | VAMP2 | 0.727815 | 3 | 0 | 3 |
| BCL7B | NCOA6 | 0.7262 | 3 | 0 | 3 |
| BCL7B | MON1A | 0.724609 | 4 | 0 | 3 |
| BCL7B | SPATA21 | 0.720013 | 3 | 0 | 3 |
| BCL7B | ADCK1 | 0.718971 | 3 | 0 | 3 |
| BCL7B | MS4A4A | 0.715774 | 3 | 0 | 3 |
| BCL7B | PHLDA3 | 0.709948 | 4 | 0 | 4 |
| BCL7B | PCGF6 | 0.709862 | 4 | 0 | 3 |
For details and further investigation, click here
