| Full name: pyridoxal dependent decarboxylase domain containing 1 | Alias Symbol: KIAA0251 | ||
| Type: protein-coding gene | Cytoband: 16p13.11 | ||
| Entrez ID: 23042 | HGNC ID: HGNC:28995 | Ensembl Gene: ENSG00000179889 | OMIM ID: 614244 |
| Drug and gene relationship at DGIdb | |||
Expression of PDXDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDXDC1 | 23042 | 1560014_s_at | -0.2913 | 0.4709 | |
| GSE26886 | PDXDC1 | 23042 | 1560014_s_at | -0.4552 | 0.0070 | |
| GSE45670 | PDXDC1 | 23042 | 1560014_s_at | -0.3452 | 0.0101 | |
| GSE53622 | PDXDC1 | 23042 | 57724 | -0.1941 | 0.0020 | |
| GSE53624 | PDXDC1 | 23042 | 57724 | -0.0972 | 0.1533 | |
| GSE63941 | PDXDC1 | 23042 | 1560014_s_at | -0.0277 | 0.9023 | |
| GSE77861 | PDXDC1 | 23042 | 1560014_s_at | 0.1035 | 0.3433 | |
| GSE97050 | PDXDC1 | 23042 | A_33_P3336527 | -0.0765 | 0.7482 | |
| SRP007169 | PDXDC1 | 23042 | RNAseq | -0.3104 | 0.3359 | |
| SRP008496 | PDXDC1 | 23042 | RNAseq | -0.3768 | 0.0402 | |
| SRP064894 | PDXDC1 | 23042 | RNAseq | -0.2318 | 0.2391 | |
| SRP133303 | PDXDC1 | 23042 | RNAseq | 0.1995 | 0.3142 | |
| SRP159526 | PDXDC1 | 23042 | RNAseq | -0.0865 | 0.7615 | |
| SRP193095 | PDXDC1 | 23042 | RNAseq | -0.1913 | 0.2372 | |
| SRP219564 | PDXDC1 | 23042 | RNAseq | -0.1010 | 0.7294 | |
| TCGA | PDXDC1 | 23042 | RNAseq | -0.2617 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDXDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDXDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDXDC1 | 23042 | 5 | 4 | 21 | |
| GSE20123 | PDXDC1 | 23042 | 5 | 3 | 22 | |
| GSE43470 | PDXDC1 | 23042 | 3 | 3 | 37 | |
| GSE46452 | PDXDC1 | 23042 | 38 | 1 | 20 | |
| GSE47630 | PDXDC1 | 23042 | 11 | 6 | 23 | |
| GSE54993 | PDXDC1 | 23042 | 3 | 5 | 62 | |
| GSE54994 | PDXDC1 | 23042 | 4 | 10 | 39 | |
| GSE60625 | PDXDC1 | 23042 | 4 | 1 | 6 | |
| GSE74703 | PDXDC1 | 23042 | 3 | 2 | 31 | |
| GSE74704 | PDXDC1 | 23042 | 2 | 1 | 17 | |
| TCGA | PDXDC1 | 23042 | 20 | 12 | 64 |
Total number of gains: 98; Total number of losses: 48; Total Number of normals: 342.
Somatic mutations of PDXDC1:
Generating mutation plots.
Highly correlated genes for PDXDC1:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDXDC1 | INO80D | 0.770228 | 3 | 0 | 3 |
| PDXDC1 | WDR59 | 0.763197 | 3 | 0 | 3 |
| PDXDC1 | KLC1 | 0.749102 | 3 | 0 | 3 |
| PDXDC1 | HNRNPA1 | 0.732996 | 3 | 0 | 3 |
| PDXDC1 | APH1A | 0.732591 | 3 | 0 | 3 |
| PDXDC1 | DHX15 | 0.711997 | 3 | 0 | 3 |
| PDXDC1 | UBQLN1 | 0.705587 | 3 | 0 | 3 |
| PDXDC1 | RBPJ | 0.691948 | 3 | 0 | 3 |
| PDXDC1 | SLC38A4 | 0.687958 | 3 | 0 | 3 |
| PDXDC1 | SUN1 | 0.684699 | 4 | 0 | 4 |
| PDXDC1 | RPL27A | 0.684311 | 3 | 0 | 3 |
| PDXDC1 | MAP4K5 | 0.683524 | 3 | 0 | 3 |
| PDXDC1 | AP1G1 | 0.680551 | 3 | 0 | 3 |
| PDXDC1 | ZBED6 | 0.679425 | 4 | 0 | 4 |
| PDXDC1 | ACYP1 | 0.678908 | 3 | 0 | 3 |
| PDXDC1 | KDM1A | 0.677079 | 3 | 0 | 3 |
| PDXDC1 | AKAP17A | 0.668988 | 3 | 0 | 3 |
| PDXDC1 | ZNF330 | 0.664888 | 3 | 0 | 3 |
| PDXDC1 | MAGI1 | 0.660519 | 3 | 0 | 3 |
| PDXDC1 | GADD45A | 0.655245 | 4 | 0 | 4 |
For details and further investigation, click here
