| Full name: hippocalcin like 4 | Alias Symbol: HLP4|DKFZp761G122 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 51440 | HGNC ID: HGNC:18212 | Ensembl Gene: ENSG00000116983 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HPCAL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HPCAL4 | 51440 | 222091_at | 0.0534 | 0.8282 | |
| GSE20347 | HPCAL4 | 51440 | 222091_at | -0.0282 | 0.7507 | |
| GSE23400 | HPCAL4 | 51440 | 219671_at | -0.2281 | 0.0000 | |
| GSE26886 | HPCAL4 | 51440 | 222091_at | 0.2220 | 0.0068 | |
| GSE29001 | HPCAL4 | 51440 | 222091_at | -0.0081 | 0.9606 | |
| GSE38129 | HPCAL4 | 51440 | 222091_at | -0.0869 | 0.2334 | |
| GSE45670 | HPCAL4 | 51440 | 222091_at | -0.0502 | 0.5395 | |
| GSE53622 | HPCAL4 | 51440 | 62328 | -3.7026 | 0.0000 | |
| GSE53624 | HPCAL4 | 51440 | 62328 | -3.3530 | 0.0000 | |
| GSE63941 | HPCAL4 | 51440 | 222091_at | 0.2817 | 0.0446 | |
| GSE77861 | HPCAL4 | 51440 | 222091_at | -0.0621 | 0.5320 | |
| SRP064894 | HPCAL4 | 51440 | RNAseq | -3.5278 | 0.0000 | |
| SRP133303 | HPCAL4 | 51440 | RNAseq | -3.2160 | 0.0000 | |
| SRP159526 | HPCAL4 | 51440 | RNAseq | -3.0968 | 0.0000 | |
| TCGA | HPCAL4 | 51440 | RNAseq | -1.3152 | 0.0032 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by HPCAL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HPCAL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HPCAL4 | 51440 | 3 | 4 | 23 | |
| GSE20123 | HPCAL4 | 51440 | 2 | 3 | 25 | |
| GSE43470 | HPCAL4 | 51440 | 8 | 2 | 33 | |
| GSE46452 | HPCAL4 | 51440 | 4 | 1 | 54 | |
| GSE47630 | HPCAL4 | 51440 | 9 | 2 | 29 | |
| GSE54993 | HPCAL4 | 51440 | 0 | 1 | 69 | |
| GSE54994 | HPCAL4 | 51440 | 13 | 2 | 38 | |
| GSE60625 | HPCAL4 | 51440 | 0 | 0 | 11 | |
| GSE74703 | HPCAL4 | 51440 | 7 | 1 | 28 | |
| GSE74704 | HPCAL4 | 51440 | 1 | 0 | 19 | |
| TCGA | HPCAL4 | 51440 | 16 | 16 | 64 |
Total number of gains: 63; Total number of losses: 32; Total Number of normals: 393.
Somatic mutations of HPCAL4:
Generating mutation plots.
Highly correlated genes for HPCAL4:
Showing top 20/615 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HPCAL4 | SUGCT | 0.716176 | 3 | 0 | 3 |
| HPCAL4 | GCG | 0.715766 | 4 | 0 | 4 |
| HPCAL4 | MYEF2 | 0.694117 | 4 | 0 | 4 |
| HPCAL4 | AMN | 0.689197 | 6 | 0 | 5 |
| HPCAL4 | TRMT10B | 0.689017 | 3 | 0 | 3 |
| HPCAL4 | CT55 | 0.685397 | 3 | 0 | 3 |
| HPCAL4 | ARMC5 | 0.68356 | 3 | 0 | 3 |
| HPCAL4 | ZMIZ2 | 0.679618 | 3 | 0 | 3 |
| HPCAL4 | OR10H3 | 0.679009 | 4 | 0 | 3 |
| HPCAL4 | PSPN | 0.673194 | 3 | 0 | 3 |
| HPCAL4 | TEAD3 | 0.672662 | 4 | 0 | 3 |
| HPCAL4 | CST8 | 0.671326 | 4 | 0 | 4 |
| HPCAL4 | LRTM1 | 0.670673 | 4 | 0 | 4 |
| HPCAL4 | NTNG1 | 0.669402 | 5 | 0 | 5 |
| HPCAL4 | KMT2D | 0.669271 | 4 | 0 | 4 |
| HPCAL4 | SARDH | 0.667731 | 5 | 0 | 4 |
| HPCAL4 | GGT5 | 0.666307 | 3 | 0 | 3 |
| HPCAL4 | GDF2 | 0.660281 | 7 | 0 | 7 |
| HPCAL4 | MAPK4 | 0.659983 | 5 | 0 | 4 |
| HPCAL4 | KRT83 | 0.657414 | 5 | 0 | 5 |
For details and further investigation, click here
