| Full name: TEA domain transcription factor 3 | Alias Symbol: TEF-5|ETFR-1 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 7005 | HGNC ID: HGNC:11716 | Ensembl Gene: ENSG00000007866 | OMIM ID: 603170 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
TEAD3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04390 | Hippo signaling pathway |
Expression of TEAD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TEAD3 | 7005 | 209454_s_at | -0.0573 | 0.9518 | |
| GSE20347 | TEAD3 | 7005 | 209454_s_at | -0.2930 | 0.0044 | |
| GSE23400 | TEAD3 | 7005 | 209454_s_at | -0.3939 | 0.0000 | |
| GSE26886 | TEAD3 | 7005 | 209454_s_at | -0.0108 | 0.9559 | |
| GSE29001 | TEAD3 | 7005 | 209454_s_at | -0.2064 | 0.3291 | |
| GSE38129 | TEAD3 | 7005 | 209454_s_at | -0.4177 | 0.0129 | |
| GSE45670 | TEAD3 | 7005 | 209454_s_at | -0.2989 | 0.0306 | |
| GSE53622 | TEAD3 | 7005 | 52497 | -2.2311 | 0.0000 | |
| GSE53624 | TEAD3 | 7005 | 52497 | -2.2454 | 0.0000 | |
| GSE63941 | TEAD3 | 7005 | 209454_s_at | -0.4714 | 0.2629 | |
| GSE77861 | TEAD3 | 7005 | 209454_s_at | -0.2153 | 0.3347 | |
| GSE97050 | TEAD3 | 7005 | A_23_P82000 | -1.1226 | 0.1065 | |
| SRP007169 | TEAD3 | 7005 | RNAseq | -1.2185 | 0.0012 | |
| SRP008496 | TEAD3 | 7005 | RNAseq | -1.1481 | 0.0000 | |
| SRP064894 | TEAD3 | 7005 | RNAseq | -0.5393 | 0.0004 | |
| SRP133303 | TEAD3 | 7005 | RNAseq | -0.2876 | 0.1756 | |
| SRP159526 | TEAD3 | 7005 | RNAseq | -0.3352 | 0.2415 | |
| SRP193095 | TEAD3 | 7005 | RNAseq | -0.2510 | 0.0573 | |
| SRP219564 | TEAD3 | 7005 | RNAseq | -0.5608 | 0.1573 | |
| TCGA | TEAD3 | 7005 | RNAseq | -0.0341 | 0.5423 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TEAD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TEAD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TEAD3 | 7005 | 5 | 0 | 25 | |
| GSE20123 | TEAD3 | 7005 | 5 | 0 | 25 | |
| GSE43470 | TEAD3 | 7005 | 5 | 1 | 37 | |
| GSE46452 | TEAD3 | 7005 | 2 | 9 | 48 | |
| GSE47630 | TEAD3 | 7005 | 8 | 4 | 28 | |
| GSE54993 | TEAD3 | 7005 | 3 | 1 | 66 | |
| GSE54994 | TEAD3 | 7005 | 11 | 4 | 38 | |
| GSE60625 | TEAD3 | 7005 | 1 | 0 | 10 | |
| GSE74703 | TEAD3 | 7005 | 5 | 0 | 31 | |
| GSE74704 | TEAD3 | 7005 | 2 | 0 | 18 | |
| TCGA | TEAD3 | 7005 | 15 | 15 | 66 |
Total number of gains: 62; Total number of losses: 34; Total Number of normals: 392.
Somatic mutations of TEAD3:
Generating mutation plots.
Highly correlated genes for TEAD3:
Showing top 20/753 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TEAD3 | CASC3 | 0.854384 | 3 | 0 | 3 |
| TEAD3 | THSD4 | 0.851755 | 3 | 0 | 3 |
| TEAD3 | UCP3 | 0.826676 | 3 | 0 | 3 |
| TEAD3 | SLC10A5 | 0.821222 | 3 | 0 | 3 |
| TEAD3 | NCR1 | 0.817347 | 3 | 0 | 3 |
| TEAD3 | CA13 | 0.816911 | 3 | 0 | 3 |
| TEAD3 | IL34 | 0.802865 | 3 | 0 | 3 |
| TEAD3 | EPGN | 0.802856 | 3 | 0 | 3 |
| TEAD3 | SH3BGRL2 | 0.779652 | 4 | 0 | 3 |
| TEAD3 | LNX1 | 0.772789 | 4 | 0 | 4 |
| TEAD3 | UPK3B | 0.766705 | 3 | 0 | 3 |
| TEAD3 | LIN54 | 0.75951 | 3 | 0 | 3 |
| TEAD3 | HTR3B | 0.753515 | 3 | 0 | 3 |
| TEAD3 | PAQR8 | 0.752142 | 3 | 0 | 3 |
| TEAD3 | KAZN | 0.748067 | 5 | 0 | 5 |
| TEAD3 | MTPN | 0.747721 | 3 | 0 | 3 |
| TEAD3 | KCNQ2 | 0.745316 | 4 | 0 | 4 |
| TEAD3 | OSTF1 | 0.741912 | 4 | 0 | 4 |
| TEAD3 | FAM3D | 0.737042 | 4 | 0 | 3 |
| TEAD3 | ECHDC3 | 0.731211 | 3 | 0 | 3 |
For details and further investigation, click here
