| Full name: keratin 83 | Alias Symbol: Hb-3 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3889 | HGNC ID: HGNC:6460 | Ensembl Gene: ENSG00000170523 | OMIM ID: 602765 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT83:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT83 | 3889 | 207669_at | -0.0640 | 0.7944 | |
| GSE20347 | KRT83 | 3889 | 207669_at | -0.1100 | 0.1287 | |
| GSE23400 | KRT83 | 3889 | 207669_at | -0.0915 | 0.0056 | |
| GSE26886 | KRT83 | 3889 | 207669_at | -0.0246 | 0.8431 | |
| GSE29001 | KRT83 | 3889 | 207669_at | -0.1186 | 0.4677 | |
| GSE38129 | KRT83 | 3889 | 207669_at | -0.1337 | 0.0144 | |
| GSE45670 | KRT83 | 3889 | 207669_at | -0.0121 | 0.9013 | |
| GSE53622 | KRT83 | 3889 | 126734 | -2.0377 | 0.0000 | |
| GSE53624 | KRT83 | 3889 | 126734 | -2.1750 | 0.0000 | |
| GSE63941 | KRT83 | 3889 | 207669_at | 0.2793 | 0.1342 | |
| GSE77861 | KRT83 | 3889 | 207669_at | -0.1396 | 0.2608 | |
| GSE97050 | KRT83 | 3889 | A_33_P3273552 | -0.7264 | 0.5869 | |
| TCGA | KRT83 | 3889 | RNAseq | 2.7428 | 0.0402 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by KRT83 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT83:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT83 | 3889 | 8 | 1 | 21 | |
| GSE20123 | KRT83 | 3889 | 8 | 1 | 21 | |
| GSE43470 | KRT83 | 3889 | 3 | 0 | 40 | |
| GSE46452 | KRT83 | 3889 | 7 | 1 | 51 | |
| GSE47630 | KRT83 | 3889 | 10 | 2 | 28 | |
| GSE54993 | KRT83 | 3889 | 0 | 5 | 65 | |
| GSE54994 | KRT83 | 3889 | 3 | 2 | 48 | |
| GSE60625 | KRT83 | 3889 | 0 | 0 | 11 | |
| GSE74703 | KRT83 | 3889 | 3 | 0 | 33 | |
| GSE74704 | KRT83 | 3889 | 5 | 1 | 14 | |
| TCGA | KRT83 | 3889 | 12 | 11 | 73 |
Total number of gains: 59; Total number of losses: 24; Total Number of normals: 405.
Somatic mutations of KRT83:
Generating mutation plots.
Highly correlated genes for KRT83:
Showing top 20/928 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT83 | NCCRP1 | 0.870074 | 3 | 0 | 3 |
| KRT83 | CNFN | 0.867436 | 3 | 0 | 3 |
| KRT83 | PLEKHN1 | 0.86297 | 3 | 0 | 3 |
| KRT83 | C15orf48 | 0.847896 | 3 | 0 | 3 |
| KRT83 | ZNF750 | 0.816662 | 3 | 0 | 3 |
| KRT83 | S100A10 | 0.812427 | 4 | 0 | 4 |
| KRT83 | OTOP3 | 0.80415 | 3 | 0 | 3 |
| KRT83 | TMPRSS11A | 0.802543 | 3 | 0 | 3 |
| KRT83 | KRTAP20-1 | 0.801994 | 3 | 0 | 3 |
| KRT83 | KRT6C | 0.801131 | 3 | 0 | 3 |
| KRT83 | CCDC50 | 0.798793 | 3 | 0 | 3 |
| KRT83 | CSTL1 | 0.793919 | 3 | 0 | 3 |
| KRT83 | MFSD2B | 0.792353 | 3 | 0 | 3 |
| KRT83 | SPRR2F | 0.784233 | 3 | 0 | 3 |
| KRT83 | TMEM154 | 0.782092 | 4 | 0 | 3 |
| KRT83 | KRT78 | 0.776928 | 3 | 0 | 3 |
| KRT83 | ARHGAP40 | 0.776632 | 3 | 0 | 3 |
| KRT83 | S100A16 | 0.774702 | 4 | 0 | 3 |
| KRT83 | SDCBP2 | 0.774467 | 3 | 0 | 3 |
| KRT83 | SPRR2A | 0.769676 | 3 | 0 | 3 |
For details and further investigation, click here
