| Full name: leucine rich repeats and transmembrane domains 1 | Alias Symbol: HT017 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 57408 | HGNC ID: HGNC:25023 | Ensembl Gene: ENSG00000144771 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRTM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRTM1 | 57408 | 221612_at | 0.0489 | 0.8381 | |
| GSE20347 | LRTM1 | 57408 | 221612_at | -0.0435 | 0.6269 | |
| GSE23400 | LRTM1 | 57408 | 221612_at | -0.2196 | 0.0000 | |
| GSE26886 | LRTM1 | 57408 | 221612_at | -0.0742 | 0.5632 | |
| GSE29001 | LRTM1 | 57408 | 221612_at | -0.1406 | 0.3666 | |
| GSE38129 | LRTM1 | 57408 | 221612_at | -0.0901 | 0.2467 | |
| GSE45670 | LRTM1 | 57408 | 221612_at | 0.1175 | 0.2904 | |
| GSE53622 | LRTM1 | 57408 | 11046 | 0.1658 | 0.0336 | |
| GSE53624 | LRTM1 | 57408 | 11046 | 0.2764 | 0.0001 | |
| GSE63941 | LRTM1 | 57408 | 221612_at | -0.0625 | 0.7751 | |
| GSE77861 | LRTM1 | 57408 | 221612_at | -0.1509 | 0.1606 | |
| GSE97050 | LRTM1 | 57408 | A_23_P40856 | 0.0636 | 0.7683 | |
| SRP133303 | LRTM1 | 57408 | RNAseq | -0.4478 | 0.1239 | |
| TCGA | LRTM1 | 57408 | RNAseq | 0.9205 | 0.4196 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRTM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRTM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRTM1 | 57408 | 0 | 16 | 14 | |
| GSE20123 | LRTM1 | 57408 | 0 | 17 | 13 | |
| GSE43470 | LRTM1 | 57408 | 0 | 17 | 26 | |
| GSE46452 | LRTM1 | 57408 | 2 | 18 | 39 | |
| GSE47630 | LRTM1 | 57408 | 1 | 24 | 15 | |
| GSE54993 | LRTM1 | 57408 | 6 | 2 | 62 | |
| GSE54994 | LRTM1 | 57408 | 0 | 32 | 21 | |
| GSE60625 | LRTM1 | 57408 | 5 | 0 | 6 | |
| GSE74703 | LRTM1 | 57408 | 0 | 14 | 22 | |
| GSE74704 | LRTM1 | 57408 | 0 | 11 | 9 | |
| TCGA | LRTM1 | 57408 | 0 | 81 | 15 |
Total number of gains: 14; Total number of losses: 232; Total Number of normals: 242.
Somatic mutations of LRTM1:
Generating mutation plots.
Highly correlated genes for LRTM1:
Showing top 20/1033 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRTM1 | RNF17 | 0.783146 | 5 | 0 | 5 |
| LRTM1 | UMOD | 0.774696 | 4 | 0 | 4 |
| LRTM1 | SLC9A7 | 0.768585 | 3 | 0 | 3 |
| LRTM1 | BCL2L10 | 0.765846 | 3 | 0 | 3 |
| LRTM1 | CBLN1 | 0.762935 | 4 | 0 | 4 |
| LRTM1 | TCTE1 | 0.76148 | 3 | 0 | 3 |
| LRTM1 | DEFB121 | 0.759652 | 3 | 0 | 3 |
| LRTM1 | HAND1 | 0.743915 | 4 | 0 | 4 |
| LRTM1 | KIR2DS5 | 0.742192 | 4 | 0 | 4 |
| LRTM1 | MASP2 | 0.74111 | 5 | 0 | 5 |
| LRTM1 | MEFV | 0.740131 | 3 | 0 | 3 |
| LRTM1 | TFF1 | 0.739786 | 3 | 0 | 3 |
| LRTM1 | ADORA1 | 0.738223 | 3 | 0 | 3 |
| LRTM1 | IL1F10 | 0.734025 | 3 | 0 | 3 |
| LRTM1 | C20orf141 | 0.73254 | 3 | 0 | 3 |
| LRTM1 | LACRT | 0.730591 | 3 | 0 | 3 |
| LRTM1 | KSR1 | 0.727965 | 5 | 0 | 5 |
| LRTM1 | PRR34 | 0.723501 | 4 | 0 | 4 |
| LRTM1 | KLF15 | 0.723499 | 4 | 0 | 4 |
| LRTM1 | C4BPA | 0.722812 | 5 | 0 | 5 |
For details and further investigation, click here
