| Full name: hemopexin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 3263 | HGNC ID: HGNC:5171 | Ensembl Gene: ENSG00000110169 | OMIM ID: 142290 |
| Drug and gene relationship at DGIdb | |||
Expression of HPX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HPX | 3263 | 210013_at | 0.0923 | 0.7146 | |
| GSE20347 | HPX | 3263 | 39763_at | -0.0141 | 0.9005 | |
| GSE23400 | HPX | 3263 | 210013_at | -0.1650 | 0.0000 | |
| GSE26886 | HPX | 3263 | 39763_at | 0.1075 | 0.3353 | |
| GSE29001 | HPX | 3263 | 210013_at | -0.1610 | 0.3349 | |
| GSE38129 | HPX | 3263 | 39763_at | -0.1049 | 0.4501 | |
| GSE45670 | HPX | 3263 | 39763_at | -0.0593 | 0.4771 | |
| GSE53622 | HPX | 3263 | 89566 | 0.1547 | 0.2295 | |
| GSE53624 | HPX | 3263 | 89566 | 0.4832 | 0.0000 | |
| GSE63941 | HPX | 3263 | 210013_at | 0.4895 | 0.0024 | |
| GSE77861 | HPX | 3263 | 39763_at | -0.1492 | 0.1174 | |
| GSE97050 | HPX | 3263 | A_23_P161998 | -0.0647 | 0.9071 | |
| SRP219564 | HPX | 3263 | RNAseq | -0.2536 | 0.6152 | |
| TCGA | HPX | 3263 | RNAseq | -1.2129 | 0.0041 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HPX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HPX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HPX | 3263 | 1 | 11 | 18 | |
| GSE20123 | HPX | 3263 | 1 | 11 | 18 | |
| GSE43470 | HPX | 3263 | 1 | 8 | 34 | |
| GSE46452 | HPX | 3263 | 7 | 8 | 44 | |
| GSE47630 | HPX | 3263 | 2 | 12 | 26 | |
| GSE54993 | HPX | 3263 | 3 | 1 | 66 | |
| GSE54994 | HPX | 3263 | 2 | 12 | 39 | |
| GSE60625 | HPX | 3263 | 0 | 0 | 11 | |
| GSE74703 | HPX | 3263 | 1 | 6 | 29 | |
| GSE74704 | HPX | 3263 | 0 | 8 | 12 | |
| TCGA | HPX | 3263 | 8 | 39 | 49 |
Total number of gains: 26; Total number of losses: 116; Total Number of normals: 346.
Somatic mutations of HPX:
Generating mutation plots.
Highly correlated genes for HPX:
Showing top 20/1337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HPX | USP2-AS1 | 0.766817 | 3 | 0 | 3 |
| HPX | C9orf153 | 0.759466 | 3 | 0 | 3 |
| HPX | LINC00520 | 0.754919 | 3 | 0 | 3 |
| HPX | PSG9 | 0.750938 | 4 | 0 | 4 |
| HPX | STRC | 0.743557 | 3 | 0 | 3 |
| HPX | AMHR2 | 0.725697 | 9 | 0 | 9 |
| HPX | MRGPRG | 0.723728 | 3 | 0 | 3 |
| HPX | DEFB128 | 0.723215 | 3 | 0 | 3 |
| HPX | IFNA4 | 0.721568 | 6 | 0 | 6 |
| HPX | NTNG2 | 0.72012 | 3 | 0 | 3 |
| HPX | KRTAP10-12 | 0.719785 | 3 | 0 | 3 |
| HPX | PLA2G2C | 0.719485 | 3 | 0 | 3 |
| HPX | C2orf81 | 0.717004 | 4 | 0 | 4 |
| HPX | TRPC5 | 0.716812 | 3 | 0 | 3 |
| HPX | MBL2 | 0.715147 | 3 | 0 | 3 |
| HPX | OR4D6 | 0.715121 | 3 | 0 | 3 |
| HPX | C19orf71 | 0.714862 | 3 | 0 | 3 |
| HPX | OR2T27 | 0.711999 | 3 | 0 | 3 |
| HPX | BLACE | 0.708368 | 3 | 0 | 3 |
| HPX | ART1 | 0.707604 | 7 | 0 | 6 |
For details and further investigation, click here
