| Full name: interferon alpha 4 | Alias Symbol: MGC142200|IFN-alpha4a | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 3441 | HGNC ID: HGNC:5425 | Ensembl Gene: ENSG00000236637 | OMIM ID: 147564 |
| Drug and gene relationship at DGIdb | |||
IFNA4 involved pathways:
Expression of IFNA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNA4 | 3441 | 207964_x_at | -0.0751 | 0.8104 | |
| GSE20347 | IFNA4 | 3441 | 207964_x_at | 0.0365 | 0.7198 | |
| GSE23400 | IFNA4 | 3441 | 207964_x_at | -0.1150 | 0.0136 | |
| GSE26886 | IFNA4 | 3441 | 207964_x_at | -0.1727 | 0.1128 | |
| GSE29001 | IFNA4 | 3441 | 207964_x_at | -0.0692 | 0.7396 | |
| GSE38129 | IFNA4 | 3441 | 207964_x_at | -0.0426 | 0.6169 | |
| GSE45670 | IFNA4 | 3441 | 207964_x_at | -0.0852 | 0.2089 | |
| GSE63941 | IFNA4 | 3441 | 207964_x_at | 0.1888 | 0.1786 | |
| GSE77861 | IFNA4 | 3441 | 207964_x_at | -0.0799 | 0.4024 | |
| GSE97050 | IFNA4 | 3441 | A_24_P403459 | 0.0504 | 0.8730 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNA4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IFNA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNA4 | 3441 | 2 | 17 | 11 | |
| GSE20123 | IFNA4 | 3441 | 2 | 17 | 11 | |
| GSE43470 | IFNA4 | 3441 | 4 | 13 | 26 | |
| GSE46452 | IFNA4 | 3441 | 2 | 23 | 34 | |
| GSE47630 | IFNA4 | 3441 | 3 | 27 | 10 | |
| GSE54993 | IFNA4 | 3441 | 7 | 2 | 61 | |
| GSE54994 | IFNA4 | 3441 | 8 | 16 | 29 | |
| GSE60625 | IFNA4 | 3441 | 3 | 0 | 8 | |
| GSE74703 | IFNA4 | 3441 | 4 | 10 | 22 | |
| GSE74704 | IFNA4 | 3441 | 0 | 13 | 7 | |
| TCGA | IFNA4 | 3441 | 11 | 53 | 32 |
Total number of gains: 46; Total number of losses: 191; Total Number of normals: 251.
Somatic mutations of IFNA4:
Generating mutation plots.
Highly correlated genes for IFNA4:
Showing top 20/849 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNA4 | KIR3DL3 | 0.786583 | 5 | 0 | 5 |
| IFNA4 | GRID2 | 0.772575 | 3 | 0 | 3 |
| IFNA4 | SRRM4 | 0.767702 | 3 | 0 | 3 |
| IFNA4 | FOLH1 | 0.764345 | 5 | 0 | 5 |
| IFNA4 | CPNE6 | 0.761963 | 4 | 0 | 4 |
| IFNA4 | AQP8 | 0.756366 | 5 | 0 | 5 |
| IFNA4 | PROCA1 | 0.755011 | 3 | 0 | 3 |
| IFNA4 | PPP1R14D | 0.751263 | 5 | 0 | 5 |
| IFNA4 | CYP2D6 | 0.746791 | 5 | 0 | 5 |
| IFNA4 | HECW1 | 0.745155 | 6 | 0 | 6 |
| IFNA4 | FGF14 | 0.740758 | 3 | 0 | 3 |
| IFNA4 | RNF17 | 0.739791 | 5 | 0 | 5 |
| IFNA4 | ABCC6 | 0.737057 | 3 | 0 | 3 |
| IFNA4 | FSCN3 | 0.734345 | 6 | 0 | 6 |
| IFNA4 | NOX1 | 0.734241 | 5 | 0 | 5 |
| IFNA4 | SPINK2 | 0.731809 | 4 | 0 | 4 |
| IFNA4 | FSHR | 0.728901 | 4 | 0 | 4 |
| IFNA4 | KCNAB3 | 0.726932 | 6 | 0 | 6 |
| IFNA4 | TTC39A | 0.725676 | 3 | 0 | 3 |
| IFNA4 | OR10C1 | 0.725478 | 6 | 0 | 6 |
For details and further investigation, click here
