| Full name: transient receptor potential cation channel subfamily C member 5 | Alias Symbol: PPP1R159 | ||
| Type: protein-coding gene | Cytoband: Xq23 | ||
| Entrez ID: 7224 | HGNC ID: HGNC:12337 | Ensembl Gene: ENSG00000072315 | OMIM ID: 300334 |
| Drug and gene relationship at DGIdb | |||
TRPC5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of TRPC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPC5 | 7224 | 220552_at | -0.0217 | 0.9205 | |
| GSE20347 | TRPC5 | 7224 | 220552_at | 0.0220 | 0.6716 | |
| GSE23400 | TRPC5 | 7224 | 220552_at | -0.0379 | 0.0268 | |
| GSE26886 | TRPC5 | 7224 | 220552_at | 0.0154 | 0.8881 | |
| GSE29001 | TRPC5 | 7224 | 220552_at | -0.0470 | 0.6484 | |
| GSE38129 | TRPC5 | 7224 | 220552_at | -0.0493 | 0.1763 | |
| GSE45670 | TRPC5 | 7224 | 220552_at | 0.0631 | 0.3684 | |
| GSE53622 | TRPC5 | 7224 | 92143 | -0.8995 | 0.0000 | |
| GSE53624 | TRPC5 | 7224 | 92143 | -0.5481 | 0.0000 | |
| GSE63941 | TRPC5 | 7224 | 220552_at | 0.0843 | 0.5639 | |
| GSE77861 | TRPC5 | 7224 | 220552_at | -0.0190 | 0.8231 | |
| SRP133303 | TRPC5 | 7224 | RNAseq | -0.8052 | 0.0086 | |
| TCGA | TRPC5 | 7224 | RNAseq | -2.6484 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRPC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPC5:
No record found for this gene.
Somatic mutations of TRPC5:
Generating mutation plots.
Highly correlated genes for TRPC5:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPC5 | HPX | 0.716812 | 3 | 0 | 3 |
| TRPC5 | PHF7 | 0.668647 | 4 | 0 | 4 |
| TRPC5 | SCN4A | 0.664285 | 3 | 0 | 3 |
| TRPC5 | DNMT3L | 0.64937 | 3 | 0 | 3 |
| TRPC5 | RIT2 | 0.649188 | 3 | 0 | 3 |
| TRPC5 | SLC7A10 | 0.643 | 3 | 0 | 3 |
| TRPC5 | CRISP1 | 0.642879 | 3 | 0 | 3 |
| TRPC5 | RPLP2 | 0.639156 | 3 | 0 | 3 |
| TRPC5 | ZMAT4 | 0.638904 | 3 | 0 | 3 |
| TRPC5 | C3orf36 | 0.638478 | 3 | 0 | 3 |
| TRPC5 | ALPI | 0.63736 | 3 | 0 | 3 |
| TRPC5 | CDH10 | 0.633716 | 3 | 0 | 3 |
| TRPC5 | SEC14L3 | 0.630992 | 3 | 0 | 3 |
| TRPC5 | ASIC4 | 0.630597 | 3 | 0 | 3 |
| TRPC5 | OR7E24 | 0.629797 | 4 | 0 | 3 |
| TRPC5 | PRPS1L1 | 0.6259 | 3 | 0 | 3 |
| TRPC5 | CDHR5 | 0.624744 | 3 | 0 | 3 |
| TRPC5 | CAMKV | 0.619492 | 3 | 0 | 3 |
| TRPC5 | AMHR2 | 0.618073 | 3 | 0 | 3 |
| TRPC5 | BPNT1 | 0.617861 | 3 | 0 | 3 |
For details and further investigation, click here
