| Full name: Fc receptor like 3 | Alias Symbol: FCRH3|IRTA3|IFGP3|SPAP2a|SPAP2|SPAP2b|SPAP2c|SPAP2d|SPAP2e|CD307c | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 115352 | HGNC ID: HGNC:18506 | Ensembl Gene: ENSG00000160856 | OMIM ID: 606510 |
| Drug and gene relationship at DGIdb | |||
Expression of FCRL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCRL3 | 115352 | 231093_at | -0.0094 | 0.9966 | |
| GSE26886 | FCRL3 | 115352 | 231093_at | -0.3865 | 0.0796 | |
| GSE45670 | FCRL3 | 115352 | 231093_at | 0.0579 | 0.9174 | |
| GSE53622 | FCRL3 | 115352 | 22271 | -0.2045 | 0.4496 | |
| GSE53624 | FCRL3 | 115352 | 99834 | -0.6959 | 0.0041 | |
| GSE63941 | FCRL3 | 115352 | 231093_at | 0.0161 | 0.9183 | |
| GSE77861 | FCRL3 | 115352 | 1553196_a_at | -0.0480 | 0.6155 | |
| GSE97050 | FCRL3 | 115352 | A_23_P103803 | 1.4141 | 0.1596 | |
| SRP133303 | FCRL3 | 115352 | RNAseq | -0.7237 | 0.1942 | |
| SRP219564 | FCRL3 | 115352 | RNAseq | 1.2345 | 0.0432 | |
| TCGA | FCRL3 | 115352 | RNAseq | 0.1636 | 0.7599 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FCRL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCRL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCRL3 | 115352 | 9 | 1 | 20 | |
| GSE20123 | FCRL3 | 115352 | 9 | 0 | 21 | |
| GSE43470 | FCRL3 | 115352 | 7 | 2 | 34 | |
| GSE46452 | FCRL3 | 115352 | 2 | 1 | 56 | |
| GSE47630 | FCRL3 | 115352 | 14 | 0 | 26 | |
| GSE54993 | FCRL3 | 115352 | 0 | 5 | 65 | |
| GSE54994 | FCRL3 | 115352 | 16 | 0 | 37 | |
| GSE60625 | FCRL3 | 115352 | 0 | 0 | 11 | |
| GSE74703 | FCRL3 | 115352 | 7 | 2 | 27 | |
| GSE74704 | FCRL3 | 115352 | 4 | 0 | 16 | |
| TCGA | FCRL3 | 115352 | 38 | 2 | 56 |
Total number of gains: 106; Total number of losses: 13; Total Number of normals: 369.
Somatic mutations of FCRL3:
Generating mutation plots.
Highly correlated genes for FCRL3:
Showing top 20/234 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCRL3 | CD19 | 0.828888 | 6 | 0 | 6 |
| FCRL3 | FCRLA | 0.808499 | 7 | 0 | 7 |
| FCRL3 | CD37 | 0.806951 | 6 | 0 | 6 |
| FCRL3 | IL2RG | 0.791171 | 4 | 0 | 4 |
| FCRL3 | IKZF3 | 0.790991 | 5 | 0 | 5 |
| FCRL3 | CCR4 | 0.774381 | 3 | 0 | 3 |
| FCRL3 | STAP1 | 0.770506 | 6 | 0 | 6 |
| FCRL3 | CLEC17A | 0.753224 | 3 | 0 | 3 |
| FCRL3 | GRAP2 | 0.750757 | 3 | 0 | 3 |
| FCRL3 | CORO1A | 0.749751 | 6 | 0 | 6 |
| FCRL3 | BANK1 | 0.74535 | 7 | 0 | 7 |
| FCRL3 | CD22 | 0.742509 | 6 | 0 | 6 |
| FCRL3 | CXCL13 | 0.740742 | 6 | 0 | 6 |
| FCRL3 | TNFSF8 | 0.738693 | 4 | 0 | 4 |
| FCRL3 | CD79A | 0.732356 | 7 | 0 | 7 |
| FCRL3 | UBASH3A | 0.727297 | 4 | 0 | 4 |
| FCRL3 | POU2AF1 | 0.727119 | 4 | 0 | 4 |
| FCRL3 | CD52 | 0.725527 | 5 | 0 | 5 |
| FCRL3 | KCNA3 | 0.724354 | 5 | 0 | 4 |
| FCRL3 | PNOC | 0.709551 | 4 | 0 | 4 |
For details and further investigation, click here
