| Full name: N-acylethanolamine acid amidase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 27163 | HGNC ID: HGNC:736 | Ensembl Gene: ENSG00000138744 | OMIM ID: 607469 |
| Drug and gene relationship at DGIdb | |||
Expression of NAAA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAAA | 27163 | 227135_at | -0.8792 | 0.2376 | |
| GSE20347 | NAAA | 27163 | 214765_s_at | -1.4339 | 0.0000 | |
| GSE23400 | NAAA | 27163 | 215178_x_at | -0.1111 | 0.0018 | |
| GSE26886 | NAAA | 27163 | 227135_at | -2.6970 | 0.0000 | |
| GSE29001 | NAAA | 27163 | 215178_x_at | -0.4842 | 0.0173 | |
| GSE38129 | NAAA | 27163 | 214765_s_at | -1.2689 | 0.0000 | |
| GSE45670 | NAAA | 27163 | 227135_at | -1.4358 | 0.0000 | |
| GSE53622 | NAAA | 27163 | 887 | -1.2036 | 0.0000 | |
| GSE53624 | NAAA | 27163 | 887 | -1.5245 | 0.0000 | |
| GSE63941 | NAAA | 27163 | 214765_s_at | -1.8693 | 0.0179 | |
| GSE77861 | NAAA | 27163 | 215178_x_at | -0.2807 | 0.0434 | |
| GSE97050 | NAAA | 27163 | A_33_P3297217 | -0.0111 | 0.9806 | |
| SRP007169 | NAAA | 27163 | RNAseq | -2.1891 | 0.0000 | |
| SRP008496 | NAAA | 27163 | RNAseq | -1.7511 | 0.0000 | |
| SRP064894 | NAAA | 27163 | RNAseq | -1.3255 | 0.0000 | |
| SRP133303 | NAAA | 27163 | RNAseq | -1.1920 | 0.0000 | |
| SRP159526 | NAAA | 27163 | RNAseq | -1.5874 | 0.0000 | |
| SRP193095 | NAAA | 27163 | RNAseq | -1.2221 | 0.0000 | |
| SRP219564 | NAAA | 27163 | RNAseq | -0.8371 | 0.0352 | |
| TCGA | NAAA | 27163 | RNAseq | -0.3984 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by NAAA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAAA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAAA | 27163 | 2 | 9 | 19 | |
| GSE20123 | NAAA | 27163 | 2 | 9 | 19 | |
| GSE43470 | NAAA | 27163 | 0 | 13 | 30 | |
| GSE46452 | NAAA | 27163 | 2 | 35 | 22 | |
| GSE47630 | NAAA | 27163 | 1 | 19 | 20 | |
| GSE54993 | NAAA | 27163 | 7 | 0 | 63 | |
| GSE54994 | NAAA | 27163 | 1 | 9 | 43 | |
| GSE60625 | NAAA | 27163 | 0 | 0 | 11 | |
| GSE74703 | NAAA | 27163 | 0 | 11 | 25 | |
| GSE74704 | NAAA | 27163 | 2 | 5 | 13 | |
| TCGA | NAAA | 27163 | 17 | 30 | 49 |
Total number of gains: 34; Total number of losses: 140; Total Number of normals: 314.
Somatic mutations of NAAA:
Generating mutation plots.
Highly correlated genes for NAAA:
Showing top 20/1817 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAAA | ZNF416 | 0.761979 | 5 | 0 | 5 |
| NAAA | MAP3K19 | 0.760147 | 3 | 0 | 3 |
| NAAA | SCP2 | 0.752929 | 9 | 0 | 9 |
| NAAA | ZFAND2B | 0.745326 | 7 | 0 | 7 |
| NAAA | FBXO8 | 0.74152 | 6 | 0 | 6 |
| NAAA | DCAF10 | 0.73859 | 5 | 0 | 5 |
| NAAA | ZNF844 | 0.738293 | 7 | 0 | 6 |
| NAAA | PAQR8 | 0.73609 | 7 | 0 | 7 |
| NAAA | GPR108 | 0.733786 | 3 | 0 | 3 |
| NAAA | TMEM50A | 0.729083 | 4 | 0 | 3 |
| NAAA | CUL3 | 0.728069 | 8 | 0 | 7 |
| NAAA | C3orf38 | 0.728003 | 4 | 0 | 4 |
| NAAA | FAR1 | 0.723427 | 5 | 0 | 5 |
| NAAA | MACROD2 | 0.723234 | 4 | 0 | 4 |
| NAAA | PITHD1 | 0.723075 | 7 | 0 | 6 |
| NAAA | PLEKHA7 | 0.72291 | 7 | 0 | 6 |
| NAAA | C5orf66-AS1 | 0.722476 | 7 | 0 | 7 |
| NAAA | KIAA1211L | 0.721415 | 7 | 0 | 7 |
| NAAA | GOLGA4 | 0.720889 | 7 | 0 | 6 |
| NAAA | APH1A | 0.720127 | 4 | 0 | 3 |
For details and further investigation, click here
