| Full name: collagen type XIV alpha 1 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.12 | ||
| Entrez ID: 7373 | HGNC ID: HGNC:2191 | Ensembl Gene: ENSG00000187955 | OMIM ID: 120324 |
| Drug and gene relationship at DGIdb | |||
Expression of COL14A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL14A1 | 7373 | 212865_s_at | -1.9727 | 0.0435 | |
| GSE20347 | COL14A1 | 7373 | 212865_s_at | -1.8383 | 0.0000 | |
| GSE23400 | COL14A1 | 7373 | 212865_s_at | -1.0126 | 0.0000 | |
| GSE26886 | COL14A1 | 7373 | 212865_s_at | -0.0288 | 0.9566 | |
| GSE29001 | COL14A1 | 7373 | 212865_s_at | -1.7181 | 0.0009 | |
| GSE38129 | COL14A1 | 7373 | 212865_s_at | -2.1040 | 0.0000 | |
| GSE45670 | COL14A1 | 7373 | 212865_s_at | -3.4331 | 0.0000 | |
| GSE53622 | COL14A1 | 7373 | 13753 | -1.9822 | 0.0000 | |
| GSE53624 | COL14A1 | 7373 | 13753 | -1.4101 | 0.0000 | |
| GSE63941 | COL14A1 | 7373 | 212865_s_at | -6.6029 | 0.0000 | |
| GSE77861 | COL14A1 | 7373 | 216865_at | -0.1993 | 0.1985 | |
| GSE97050 | COL14A1 | 7373 | A_32_P80850 | -0.3785 | 0.4230 | |
| SRP007169 | COL14A1 | 7373 | RNAseq | 0.0872 | 0.8756 | |
| SRP008496 | COL14A1 | 7373 | RNAseq | 0.5435 | 0.2611 | |
| SRP064894 | COL14A1 | 7373 | RNAseq | -0.4725 | 0.3418 | |
| SRP133303 | COL14A1 | 7373 | RNAseq | -2.1635 | 0.0000 | |
| SRP159526 | COL14A1 | 7373 | RNAseq | -0.8913 | 0.1329 | |
| SRP193095 | COL14A1 | 7373 | RNAseq | -0.9268 | 0.0032 | |
| SRP219564 | COL14A1 | 7373 | RNAseq | 0.1163 | 0.8883 | |
| TCGA | COL14A1 | 7373 | RNAseq | -0.7857 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by COL14A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL14A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL14A1 | 7373 | 19 | 1 | 10 | |
| GSE20123 | COL14A1 | 7373 | 20 | 1 | 9 | |
| GSE43470 | COL14A1 | 7373 | 23 | 0 | 20 | |
| GSE46452 | COL14A1 | 7373 | 27 | 0 | 32 | |
| GSE47630 | COL14A1 | 7373 | 24 | 0 | 16 | |
| GSE54993 | COL14A1 | 7373 | 0 | 20 | 50 | |
| GSE54994 | COL14A1 | 7373 | 38 | 0 | 15 | |
| GSE60625 | COL14A1 | 7373 | 0 | 4 | 7 | |
| GSE74703 | COL14A1 | 7373 | 19 | 0 | 17 | |
| GSE74704 | COL14A1 | 7373 | 13 | 1 | 6 | |
| TCGA | COL14A1 | 7373 | 67 | 2 | 27 |
Total number of gains: 250; Total number of losses: 29; Total Number of normals: 209.
Somatic mutations of COL14A1:
Generating mutation plots.
Highly correlated genes for COL14A1:
Showing top 20/1531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL14A1 | EBF1 | 0.847081 | 6 | 0 | 6 |
| COL14A1 | CLEC3B | 0.839413 | 3 | 0 | 3 |
| COL14A1 | FIBIN | 0.837805 | 4 | 0 | 4 |
| COL14A1 | CYP21A2 | 0.837059 | 3 | 0 | 3 |
| COL14A1 | C11orf96 | 0.826222 | 4 | 0 | 4 |
| COL14A1 | ABCA8 | 0.825559 | 11 | 0 | 10 |
| COL14A1 | MRVI1 | 0.822279 | 6 | 0 | 6 |
| COL14A1 | PREX2 | 0.813671 | 4 | 0 | 4 |
| COL14A1 | PDZRN3-AS1 | 0.809166 | 3 | 0 | 3 |
| COL14A1 | CCL14 | 0.796272 | 3 | 0 | 3 |
| COL14A1 | TCF21 | 0.793075 | 10 | 0 | 10 |
| COL14A1 | CXCL12 | 0.791121 | 11 | 0 | 10 |
| COL14A1 | AOC3 | 0.789816 | 10 | 0 | 10 |
| COL14A1 | RCAN2 | 0.789601 | 11 | 0 | 11 |
| COL14A1 | HMCN1 | 0.780967 | 5 | 0 | 5 |
| COL14A1 | TMEM100 | 0.780855 | 10 | 0 | 10 |
| COL14A1 | CLDN5 | 0.780166 | 8 | 0 | 8 |
| COL14A1 | ZNF407 | 0.778064 | 3 | 0 | 3 |
| COL14A1 | PDE1A | 0.77238 | 10 | 0 | 9 |
| COL14A1 | S1PR1 | 0.770851 | 10 | 0 | 10 |
For details and further investigation, click here
