| Full name: TBC1 domain family member 10C | Alias Symbol: FLJ00332|Carabin|EPI64C | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 374403 | HGNC ID: HGNC:24702 | Ensembl Gene: ENSG00000175463 | OMIM ID: 610831 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TBC1D10C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D10C | 374403 | 228258_at | 0.1599 | 0.8677 | |
| GSE26886 | TBC1D10C | 374403 | 228258_at | -0.2914 | 0.0725 | |
| GSE45670 | TBC1D10C | 374403 | 228258_at | -0.0871 | 0.6329 | |
| GSE53622 | TBC1D10C | 374403 | 80480 | -0.2738 | 0.0011 | |
| GSE53624 | TBC1D10C | 374403 | 21434 | -0.5351 | 0.0000 | |
| GSE63941 | TBC1D10C | 374403 | 228258_at | 0.0291 | 0.8827 | |
| GSE77861 | TBC1D10C | 374403 | 228258_at | -0.2486 | 0.0860 | |
| GSE97050 | TBC1D10C | 374403 | A_33_P3328559 | 0.7513 | 0.2094 | |
| SRP064894 | TBC1D10C | 374403 | RNAseq | 0.2129 | 0.5580 | |
| SRP133303 | TBC1D10C | 374403 | RNAseq | -0.9594 | 0.0005 | |
| SRP159526 | TBC1D10C | 374403 | RNAseq | -1.3638 | 0.0844 | |
| SRP193095 | TBC1D10C | 374403 | RNAseq | -0.2336 | 0.3993 | |
| SRP219564 | TBC1D10C | 374403 | RNAseq | 0.1443 | 0.7311 | |
| TCGA | TBC1D10C | 374403 | RNAseq | -0.1170 | 0.6091 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D10C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D10C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D10C | 374403 | 9 | 4 | 17 | |
| GSE20123 | TBC1D10C | 374403 | 9 | 4 | 17 | |
| GSE43470 | TBC1D10C | 374403 | 6 | 1 | 36 | |
| GSE46452 | TBC1D10C | 374403 | 13 | 3 | 43 | |
| GSE47630 | TBC1D10C | 374403 | 8 | 5 | 27 | |
| GSE54993 | TBC1D10C | 374403 | 3 | 1 | 66 | |
| GSE54994 | TBC1D10C | 374403 | 13 | 4 | 36 | |
| GSE60625 | TBC1D10C | 374403 | 0 | 3 | 8 | |
| GSE74703 | TBC1D10C | 374403 | 4 | 0 | 32 | |
| GSE74704 | TBC1D10C | 374403 | 7 | 2 | 11 | |
| TCGA | TBC1D10C | 374403 | 29 | 8 | 59 |
Total number of gains: 101; Total number of losses: 35; Total Number of normals: 352.
Somatic mutations of TBC1D10C:
Generating mutation plots.
Highly correlated genes for TBC1D10C:
Showing top 20/298 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D10C | FMNL1 | 0.817543 | 3 | 0 | 3 |
| TBC1D10C | CPNE7 | 0.78742 | 3 | 0 | 3 |
| TBC1D10C | CD52 | 0.777478 | 7 | 0 | 7 |
| TBC1D10C | AKNA | 0.774522 | 5 | 0 | 5 |
| TBC1D10C | CD48 | 0.773387 | 7 | 0 | 7 |
| TBC1D10C | PTPRCAP | 0.761663 | 6 | 0 | 5 |
| TBC1D10C | PSTPIP1 | 0.754422 | 4 | 0 | 4 |
| TBC1D10C | ZNF341 | 0.753667 | 3 | 0 | 3 |
| TBC1D10C | C7orf61 | 0.751256 | 3 | 0 | 3 |
| TBC1D10C | TRG-AS1 | 0.749641 | 3 | 0 | 3 |
| TBC1D10C | IKZF3 | 0.7429 | 4 | 0 | 4 |
| TBC1D10C | CD37 | 0.741351 | 5 | 0 | 5 |
| TBC1D10C | PLD4 | 0.739594 | 3 | 0 | 3 |
| TBC1D10C | BMF | 0.736393 | 3 | 0 | 3 |
| TBC1D10C | ICAM3 | 0.73412 | 6 | 0 | 6 |
| TBC1D10C | PHF7 | 0.732768 | 3 | 0 | 3 |
| TBC1D10C | C4BPA | 0.730534 | 3 | 0 | 3 |
| TBC1D10C | CEBPE | 0.729056 | 3 | 0 | 3 |
| TBC1D10C | MAP4K1 | 0.726152 | 5 | 0 | 5 |
| TBC1D10C | CD3D | 0.720169 | 6 | 0 | 6 |
For details and further investigation, click here
