| Full name: intraflagellar transport 140 | Alias Symbol: gs114|KIAA0590 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 9742 | HGNC ID: HGNC:29077 | Ensembl Gene: ENSG00000187535 | OMIM ID: 614620 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT140:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT140 | 9742 | 232844_at | 0.0635 | 0.7742 | |
| GSE20347 | IFT140 | 9742 | 204792_s_at | 0.1339 | 0.1440 | |
| GSE23400 | IFT140 | 9742 | 204792_s_at | 0.0016 | 0.9579 | |
| GSE26886 | IFT140 | 9742 | 204792_s_at | 0.4224 | 0.0108 | |
| GSE29001 | IFT140 | 9742 | 204792_s_at | 0.0388 | 0.8131 | |
| GSE38129 | IFT140 | 9742 | 204792_s_at | 0.0799 | 0.4537 | |
| GSE45670 | IFT140 | 9742 | 204792_s_at | -0.0810 | 0.4927 | |
| GSE53622 | IFT140 | 9742 | 55080 | 0.3264 | 0.0087 | |
| GSE53624 | IFT140 | 9742 | 55080 | 0.2782 | 0.0140 | |
| GSE63941 | IFT140 | 9742 | 232844_at | 0.0865 | 0.5852 | |
| GSE77861 | IFT140 | 9742 | 204792_s_at | 0.0204 | 0.8219 | |
| GSE97050 | IFT140 | 9742 | A_23_P140725 | 0.1387 | 0.5751 | |
| SRP007169 | IFT140 | 9742 | RNAseq | 0.7284 | 0.2182 | |
| SRP064894 | IFT140 | 9742 | RNAseq | 0.1840 | 0.3770 | |
| SRP133303 | IFT140 | 9742 | RNAseq | 0.1922 | 0.3267 | |
| SRP159526 | IFT140 | 9742 | RNAseq | 0.5876 | 0.0316 | |
| SRP193095 | IFT140 | 9742 | RNAseq | 0.4209 | 0.0031 | |
| SRP219564 | IFT140 | 9742 | RNAseq | 0.1313 | 0.6887 | |
| TCGA | IFT140 | 9742 | RNAseq | -0.0993 | 0.1352 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFT140 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT140:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT140 | 9742 | 5 | 5 | 20 | |
| GSE20123 | IFT140 | 9742 | 5 | 4 | 21 | |
| GSE43470 | IFT140 | 9742 | 4 | 7 | 32 | |
| GSE46452 | IFT140 | 9742 | 38 | 1 | 20 | |
| GSE47630 | IFT140 | 9742 | 13 | 6 | 21 | |
| GSE54993 | IFT140 | 9742 | 3 | 5 | 62 | |
| GSE54994 | IFT140 | 9742 | 5 | 9 | 39 | |
| GSE60625 | IFT140 | 9742 | 4 | 0 | 7 | |
| GSE74703 | IFT140 | 9742 | 4 | 5 | 27 | |
| GSE74704 | IFT140 | 9742 | 3 | 2 | 15 | |
| TCGA | IFT140 | 9742 | 19 | 15 | 62 |
Total number of gains: 103; Total number of losses: 59; Total Number of normals: 326.
Somatic mutations of IFT140:
Generating mutation plots.
Highly correlated genes for IFT140:
Showing top 20/350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT140 | ULK1 | 0.789961 | 3 | 0 | 3 |
| IFT140 | SH2B2 | 0.762476 | 3 | 0 | 3 |
| IFT140 | NXT1 | 0.723278 | 3 | 0 | 3 |
| IFT140 | ZNF595 | 0.714432 | 3 | 0 | 3 |
| IFT140 | ERP29 | 0.705106 | 3 | 0 | 3 |
| IFT140 | KIAA0513 | 0.702308 | 3 | 0 | 3 |
| IFT140 | LAGE3 | 0.698397 | 3 | 0 | 3 |
| IFT140 | SLC16A4 | 0.694587 | 3 | 0 | 3 |
| IFT140 | PIN4 | 0.692538 | 3 | 0 | 3 |
| IFT140 | DPP7 | 0.692216 | 3 | 0 | 3 |
| IFT140 | MFGE8 | 0.689949 | 5 | 0 | 5 |
| IFT140 | ZFAND3 | 0.689844 | 3 | 0 | 3 |
| IFT140 | GTF2IRD1 | 0.687922 | 3 | 0 | 3 |
| IFT140 | RAMP1 | 0.686724 | 3 | 0 | 3 |
| IFT140 | ZNF805 | 0.685272 | 4 | 0 | 3 |
| IFT140 | CD151 | 0.684158 | 3 | 0 | 3 |
| IFT140 | LRCH3 | 0.682096 | 5 | 0 | 4 |
| IFT140 | RRP1B | 0.679089 | 3 | 0 | 3 |
| IFT140 | RIMKLB | 0.678584 | 3 | 0 | 3 |
| IFT140 | GRAMD1A | 0.677481 | 4 | 0 | 3 |
For details and further investigation, click here
