| Full name: L antigen family member 3 | Alias Symbol: ITBA2|CVG5|DXS9951E|DXS9879E|ESO3|Pcc1 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 8270 | HGNC ID: HGNC:26058 | Ensembl Gene: ENSG00000196976 | OMIM ID: 300060 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LAGE3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAGE3 | 8270 | 219061_s_at | 0.8858 | 0.0502 | |
| GSE20347 | LAGE3 | 8270 | 219061_s_at | 0.8812 | 0.0002 | |
| GSE23400 | LAGE3 | 8270 | 219061_s_at | 0.7917 | 0.0000 | |
| GSE26886 | LAGE3 | 8270 | 219061_s_at | 1.3463 | 0.0000 | |
| GSE29001 | LAGE3 | 8270 | 219061_s_at | 0.8139 | 0.0364 | |
| GSE38129 | LAGE3 | 8270 | 219061_s_at | 0.9024 | 0.0000 | |
| GSE45670 | LAGE3 | 8270 | 219061_s_at | 0.7526 | 0.0010 | |
| GSE53622 | LAGE3 | 8270 | 16457 | 0.8101 | 0.0000 | |
| GSE53624 | LAGE3 | 8270 | 16457 | 1.1501 | 0.0000 | |
| GSE63941 | LAGE3 | 8270 | 219061_s_at | 0.9293 | 0.0637 | |
| GSE77861 | LAGE3 | 8270 | 219061_s_at | 0.4222 | 0.2054 | |
| GSE97050 | LAGE3 | 8270 | A_23_P73763 | 0.6827 | 0.1550 | |
| SRP007169 | LAGE3 | 8270 | RNAseq | 0.1456 | 0.7261 | |
| SRP008496 | LAGE3 | 8270 | RNAseq | 0.6321 | 0.1567 | |
| SRP064894 | LAGE3 | 8270 | RNAseq | 1.9005 | 0.0000 | |
| SRP133303 | LAGE3 | 8270 | RNAseq | 0.8978 | 0.0009 | |
| SRP159526 | LAGE3 | 8270 | RNAseq | 1.0261 | 0.0024 | |
| SRP193095 | LAGE3 | 8270 | RNAseq | 0.7166 | 0.0001 | |
| SRP219564 | LAGE3 | 8270 | RNAseq | 0.8152 | 0.0951 | |
| TCGA | LAGE3 | 8270 | RNAseq | 0.3731 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by LAGE3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LAGE3:
No record found for this gene.
Somatic mutations of LAGE3:
Generating mutation plots.
Highly correlated genes for LAGE3:
Showing top 20/2099 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAGE3 | KRTCAP2 | 0.801737 | 5 | 0 | 5 |
| LAGE3 | ZNF584 | 0.78893 | 3 | 0 | 3 |
| LAGE3 | ZNF707 | 0.775766 | 3 | 0 | 3 |
| LAGE3 | MRPL41 | 0.759722 | 3 | 0 | 3 |
| LAGE3 | UBQLN4 | 0.754179 | 5 | 0 | 5 |
| LAGE3 | COMMD5 | 0.7443 | 4 | 0 | 4 |
| LAGE3 | KDM6B | 0.743506 | 3 | 0 | 3 |
| LAGE3 | SLC25A29 | 0.740102 | 3 | 0 | 3 |
| LAGE3 | NAA11 | 0.738084 | 3 | 0 | 3 |
| LAGE3 | ZNF324B | 0.737551 | 3 | 0 | 3 |
| LAGE3 | DGKH | 0.737439 | 4 | 0 | 4 |
| LAGE3 | CXCL16 | 0.731608 | 5 | 0 | 5 |
| LAGE3 | BRAT1 | 0.730178 | 7 | 0 | 7 |
| LAGE3 | B3GALT6 | 0.728517 | 6 | 0 | 5 |
| LAGE3 | XPO5 | 0.728205 | 7 | 0 | 7 |
| LAGE3 | MRPL47 | 0.727191 | 6 | 0 | 6 |
| LAGE3 | CCM2 | 0.726794 | 7 | 0 | 6 |
| LAGE3 | SNAP47 | 0.726613 | 3 | 0 | 3 |
| LAGE3 | ERVW-1 | 0.721304 | 3 | 0 | 3 |
| LAGE3 | PPP1R16A | 0.719817 | 5 | 0 | 4 |
For details and further investigation, click here
